135 research outputs found
Vernon Elementary School, division 11 (grade 5) class
No full textTeacher: Mrs. Ivy Wisemiller. 1st row, from the left: [Dick], Paul Mitchell, Bruce Carpenter, Don Bradley, [Ken], [Wilbert], [Elmer], Jack Webster, Jim Embleton, Jim Blazer. 2nd row: _, Patsy Brown, Pat Welker, [Wanda M.], [Sharon Chill], _, Sylvia Drabuik, Judy [H], Sylvia Mykituik, Donna Hawkins, Gayle Valair, _. 3rd row: Sheila Davidson, Jacquie Maynard, Peggy Kolmaticki, Charlotte Fuhr, Arlene Kermode, Penny Peters, Lynn Stewart, Gustine Schuster, _. 4th row: Fred Gotnick, Otto [H.], Rudy Gillert, David Falconer, David Veceray, Dale, Glenn Jones, [Manfred], Ralph Mann, [Harold Gilete], Henri Larto
What Determines Family Structure?
No full textWe estimate the effects of policy and labor market variables on the fertility, union formation and dissolution, type of union (cohabiting versus married), and partner choices of the NLSY79 cohort of women. These demographic behaviors interact to determine the family structure experienced by the children of these women: living with the biological mother and the married or cohabiting biological father, a married or cohabiting step father, or no man. We find that the average wage rates available to men and women have substantial effects on family structure for children of black and Hispanic mothers, but not for whites. The tax treatment of children also affects family structure. Implementation of welfare reform and passage of unilateral divorce laws had much smaller effects on family structure for the children of this cohort of women, as did changes in welfare benefits. The estimates imply that observed changes from the 1970s to the 2000s in the policy and labor market variables considered here contributed to a reduction in the proportion of time spent living without a father by children of the NLSY79 cohort of women. This suggests that the observed increase in this non-traditional family structure in the U.S. in the last three decades was caused by other factors.family structure
Veterinary science : humans, animals and health
No full textThis living book is a collection of open access materials bringing scientific papers to a humanities audienc
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) Protein Domains Target LipY Lipases of Pathogenic Mycobacteria to the Cell Surface via the ESX-5 Pathway
No full textThe type VII secretion system ESX-5 is a major pathway for export of PE and PPE proteins in pathogenic mycobacteria. These mycobacteria-specific protein families are characterized by conserved N-terminal domains of 100 and 180 amino acids, which contain the proline-glutamic acid (PE) and proline-proline-glutamic acid (PPE) motifs after which they are named. Here we investigated secretion of the triacylglycerol lipase LipY, which in fast-growing mycobacteria contains a signal sequence, but in slow-growing species appears to have replaced the signal peptide with a PE or PPE domain. Selected LipY homologues were expressed in wild-type Mycobacterium marinum and its corresponding ESX-5 mutant, and localization of the proteins was investigated by immunoblotting and electron microscopy. Our study shows that Mycobacterium tuberculosis PE-LipY (LipYtub) and M. marinum PPE-LipY (LipYmar) are both secreted to the bacterial surface in an ESX-5-dependent fashion. After transport, the PE/PPE domains are removed by proteolytic cleavage. In contrast, Mycobacterium gilvum LipY, which has a signal sequence, is not transported to the cell surface. Furthermore, we show that LipYtub and LipYmar require their respective PE and PPE domains for ESX-5-dependent secretion. The role of the PE domain in ESX-5 secretion was confirmed in a whole cell lipase assay, in which wild-type bacteria expressing full-length LipYtub, but not LipYtub lacking its PE domain, were shown to hydrolyze extracellular lipids. In conclusion, both PE and PPE domains contain a signal required for secretion of LipY by the ESX-5 system, and these domains are proteolytically removed upon translocation
Excess Hydrogen Bond at the Ice-Vapor Interface around 200 K
No full textPhase-resolved sum-frequency generation measurements combined with molecular dynamics simulations are employed to study the effect of temperature on the molecular arrangement of water on the basal face of ice. The topmost monolayer, interrogated through its nonhydrogen-bonded, free O-H stretch peak, exhibits a maximum in surface H-bond density around 200 K. This maximum results from two competing effects: above 200 K, thermal fluctuations cause the breaking of H bonds; below 200 K, the formation of bulklike crystalline interfacial structures leads to H-bond breaking. Knowledge of the surface structure of ice is critical for understanding reactions occurring on ice surfaces and ice nucleation.Max Planck Society; Netherlands Organisation for Scientific Research (NWO); NSFC [11290162, 11525520]; National Key Research and Development Program of China [2016YFA0300901]SCI(E)ARTICLE1311
Quantitation of bilirubin conjugates with high‐performance liquid chromatography in patients with low total serum bilirubin levels
No full textAssociation of aspirin use with vitamin B12 deficiency (results of the BACH study).
No full textContains fulltext :
58513.pdf (Publisher’s version ) (Closed access)We examined the prevalence of vitamin B(12) deficiency and its association with medication use and characteristics, including infection with Helicobacter pylori (H. pylori), in 255 patients hospitalized for cardiovascular disease. In almost half of the study population, vitamin B(12) deficiency was found; patients using acetylsalicylic acid were more frequently vitamin B(12) deficient in comparison to nonusers (p = 0.02). Fifty-one percent of the patients were infected with H. pylori, and fewer infected patients were vitamin B(12) deficient
Authors' response: Relationships between the adverse effects of aspirin and polymorphisms in genes encoding aspirin metabolizing enzymes
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