293 research outputs found

    Peter F. Rudge, Ministry and Management. The Study of Ecclesiastical Administration. London, Tavistock Publications, 1968

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    Vœltzel René. Peter F. Rudge, Ministry and Management. The Study of Ecclesiastical Administration. London, Tavistock Publications, 1968. In: Revue d'histoire et de philosophie religieuses, 49e année n°2,1969. p. 205

    Connecting non-traditional, regional creative clusters to global sector and research networks.

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    Over the last two years, Peter Rudge, Associate Professor of Motion Picture Industries at Staffordshire University, has led a programme of research into the development of a cluster initiative for companies and freelancers in the film, television games and animation industries in Staffordshire, UK In March 2017, Platform, the Moving Image Cluster for the region, officially launched, supported by regional government, the chamber of commerce and regional economic development agencies. Its mission is to lead the development of the moving image economy in Staffordshire, increasing its economic value, innovation, national and international profile and creating sustainable employment and growth. A notable element to the research and development of the cluster is that it is focused on a region that does not have a large city with a track record of inherent moving image production at its centre. The region is a mix of large rural areas and small towns but is anchored by a university with a strong record of excellence in the moving image industries. The cluster therefore grew out of a different situation than the normal ‘creative cities’ paradigm so often seen in creative clusters. Connecting Platform with other traditional and non-traditional cluster locations, from both a national and international perspective, allows new networks to be built that can add a different dimension to both creative, cultural and economic growth. For rural and semi-rural clusters, the importance of advocacy and network building cannot be overstated. Developing global links for the cluster, particularly outside of the European Union given the UK BREXIT vote in June 2016, will be particularly important. Transatlantic networks - both to the USA and the Caribbean is a key strategic aim for the cluster in the short and medium term. This presentation will focus on the importance of looking beyond the normal parameters for creative cluster development and the importance of international networking for regional creative industry networks

    How Did Kettlewell’s Experiment End?

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    The past quarter century has seen an enormous growth of interest among scholars of science and technology in both particular experimental episodes and the process of experimentation. Among the most influential accounts have been those developed by Allan Franklin (1986, 1990), Deborah Mayo (1996) and Peter Galison (1987), each of which was developed primarily with reference to examples drawn from the history of physics. One useful way to access the generality of an account of experiment is to see how it fares with reference to examples drawn from disciplines far removed from the context within which it was developed. In previous essays I examined and compared the adequacy of Franklin and Mayo’s views on experiment with reference to an episode drawn from the history of evolutionary biology, H.B.D. Kettlewell's classic studies of the phenomenon of industrial melanism (Rudge 1998, 2001). The present essay reanalyzes Kettlewell’s work once more, this time as a test of Peter Galison’s provocative account of experimentation in the sciences. Kettlewell’s investigations can indeed be interpreted within Galison’s perspective, but this appears to reflect the vagueness of many key distinctions Galison makes more than any special insights his views provide on the nature of experimentation in evolutionary biology

    Neurological aspects of lentiviral infections in animals

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    War Above the Trenches. Two-part drama-documentary for UKTV.

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    Adapted from the book Bloody April by historian Peter Hart, War Above The Trenches explores the brave new world of dogfights, aerial reconnaissance and bombing missions through the eyes of the men in the air and those fighting in the trenches below. This two-part documentary was broadcast on UKTV Yesterday channel in April 2018. Runtime 1 hr 28 min (88 min

    December 1964

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    Editor: Graham Satchell, Assistant Editor and Literary: Jennifer Cox, Photography: Peter Rudge and David Farrell, Art and Design: John Banks and Carlyle Needham, Captions: Bryan Craig, Secretary: Orel Hammond, Faculty Advisor: T. G. Lloyd, P.R. Director: Pastor D.B. Hills, P.R. President: Barry Rudge, Business Manager: Lawrence Shields, Sales Manager: Peter Truscott, Advertising Manager: Brian Faull, Printer: R.M. Printing Pty. Ltd with covers and binding by Signs Publishing Company.https://research.avondale.edu.au/jacaranda/1018/thumbnail.jp

    December 1961

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    Editor: Peter Colquhoun, Design and Art: Cecil Edwards, Barry Rudge, and John Banks, Photographer: Roger Stokes, Literary: Milton Hook, Business Manager: Alex Currie, Business Advisor: Mr G. Laxton, Sales Manager: Bill Liversidge, Advertising Manager: Paul Claus, Photographers: Leonard Lee, Michael Stroe, and Nathaniel Lian, Portraits Editor: Wayne Hanson, Secretaries: Eleanor Hawke and Jennifer Franks, Faculty Sponsor: Mr. L. Draper, Printer: Avondale Press.https://research.avondale.edu.au/jacaranda/1023/thumbnail.jp

    Rates and mechanisms of mineral carbonation in peridotite: natural processes and recipes for enhanced, in situ CO2 capture and storage

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    Near-surface reaction of CO2-bearing fluids with silicate minerals in peridotite and basalt forms solid carbonate minerals. Such processes form abundant veins and travertine deposits, particularly in association with tectonically exposed mantle peridotite. This is important in the global carbon cycle, in weathering, and in understanding physical-chemical interaction during retrograde metamorphism. Enhancing the rate of such reactions is a proposed method for geologic CO2 storage, and perhaps for direct capture of CO2 from near-surface fluids. We review, synthesize, and extend inferences from a variety of sources. We include data from studies on natural peridotite carbonation processes, carbonation kinetics, feedback between permeability and volume change via reaction-driven cracking, and proposed methods for enhancing the rate of natural mineral carbonation via in situ processes (“at the outcrop”) rather than ex situ processes (“at the smokestack”)

    Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease

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    A common presentation of inherited prion disease is Gerstmann-Sträussler-Scheinker syndrome, typically presenting with gait ataxia and painful dysaesthesiae in the legs evolving over 2-5 years. The most frequent molecular genetic diagnosis is a P102L mutation of the prion protein gene (PRNP). There is no explanation for why this clinical syndrome is so distinct from Creutzfeldt-Jakob disease, and biomarkers of the early stages of disease have not been developed. Here we aimed, first, at determining if quantitative neurophysiological assessments could predict clinical diagnosis or disability and monitor progression and, second, to determine the neuropathological basis of the initial clinical and neurophysiological findings. We investigated subjects known to carry the P102L mutation in the longitudinal observational UK National Prion Monitoring Cohort study, with serial assessments of clinical features, peripheral nerve conduction, H and F components, threshold tracking and histamine flare and itch response and neuropathological examination in some of those who died. Twenty-three subjects were studied over a period of up to 12 years, including 65 neurophysiological assessments at the same department. Six were symptomatic throughout and six became symptomatic during the study. Neurophysiological abnormalities were restricted to the lower limbs. In symptomatic patients around the time of, or shortly after, symptom onset the H-reflex was lost. Lower limb thermal thresholds were at floor/ceiling in some at presentation, in others thresholds progressively deteriorated. Itch sensation to histamine injection was lost in most symptomatic patients. In six patients with initial assessments in the asymptomatic stage of the disease, a progressive deterioration in the ability to detect warm temperatures in the feet was observed prior to clinical diagnosis and the onset of disability. All of these six patients developed objective abnormalities of either warm or cold sensation prior to the onset of significant symptoms or clinical diagnosis. Autopsy examination in five patients (including two not followed clinically) showed prion protein in the substantia gelatinosa, spinothalamic tracts, posterior columns and nuclei and in the neuropil surrounding anterior horn cells. In conclusion, sensory symptoms and loss of reflexes in Gerstmann-Sträussler-Scheinker syndrome can be explained by neuropathological changes in the spinal cord. We conclude that the sensory symptoms and loss of lower limb reflexes in Gerstmann-Sträussler-Scheinker syndrome is due to pathology in the caudal spinal cord. Neuro-physiological measures become abnormal around the time of symptom onset, prior to diagnosis, and may be of value for improved early diagnosis and for recruitment and monitoring of progression in clinical trials

    Blood Mononuclear Cell Mitochondrial Respiratory Chain Complex IV Activity Is Decreased in Multiple Sclerosis Patients : Effects of β-Interferon Treatment

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    Acknowledgments: We acknowledge the invaluable help of Dr. Peter Rudge, Consultant Neurologist, National Hospital, Queen Square London, for his help with patient recruitment. We also gratefully acknowledge financial support from the National Institute for Health Research, Biomedical Research Centre.Peer reviewe
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