112 research outputs found
The Living Transcendental - An Integrationist View of Naturalized Phenomenology
Get PDFIn this article I take on the “Transcendentalist Challenge” to naturalized phenomenology, highlighting how the ontological and methodological commitments of Merleau-Ponty’s philosophy point in the direction of an integration of the transcendental and the scientific, thus making room for a productive exchange between philosophy and psychological science when it comes to understanding consciousness and its place in nature. Discussing various conceptions of naturalized phenomenology, I argue that what I call an “Integrationist View” is required if we are to make sense of the possibility of productive exchange between phenomenology and the sciences. My main argument is that if we conceive of consciousness as a structure of behavior ontologically prior to the distinctions between objectivity and subjectivity and third- and first-person perspectives, we arrive at a view of the transcendental as not essentially separate from the domain of science, but rather as contingent organizational norms of empirical nature that are best illuminated through a dialectical exchange between phenomenological and scientific approaches. I end by showing how Merleau-Ponty’s engagement with the “Schneider case” in an example of such an integration.publishedVersionCopyright © 2020 Netland. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms
The influence of several variables on the triflouroacetic acid macromethod for the determination of serum vitamin A.
No full textDexamethasone implantation in birdshot chorioretinopathy – long-term outcome
No full textAsima Bajwa,1 Travis Peck,1 Ashvini K Reddy,2 Peter A Netland,1 Yevgeniy Shildkrot1 1Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA; 2Johns Hopkins Wilmer Eye Institute, Baltimore, MD, USA Purpose: To evaluate the long-term efficacy of the 0.70 mg dexamethasone (DEX) intravitreal implant in patients with birdshot chorioretinopathy (BSCR).Methods: Retrospective descriptive case series of BSCR patients treated with DEX implant (DEX implant 0.70 mg, DEX). Patients receiving treatment between September 2013 and November 2016 with a minimum follow-up (FU) of 12 months were included. The outcomes of primary interest were vision-related functioning, Snellen visual acuity, ocular inflammation status, presence or absence of vasculitis, change in central macular thickness, and development of glaucoma and/or cataract. Change in vision-related functioning was evaluated by comparing the National Eye Institute Visual Function Questionnaire-25. The outcomes were assessed at baseline, after DEX implant, at time of relapse, and at last FU.Results: Three patients (six eyes) were included in the study and were followed for 1–3 years. They received 1–4 DEX implants OU. All patients demonstrated improvement in National Eye Institute Visual Function Questionnaire-25 scores. Mean Snellen visual acuity better than or equal to 20/40 was seen in three eyes at baseline and five eyes at last FU. At induction, all of the patients (six eyes) had active vitritis and two (four eyes) had retinal vasculitis. All three patients (six eyes) were quiet at last FU. One patient (two eyes) developed bilateral ocular hypertension requiring topical therapy and discontinuation of DEX implants. Two patients (three eyes) developed posterior subcapsular cataract during therapy. Two patients (four eyes) showed progression of disease while on DEX therapy. All patients were eventually transitioned to systemic immunosuppressive drug therapy.Conclusion: BSCR patients receiving DEX implant experienced clinically meaningful improvements in patient-reported visual function as well as ocular inflammation. However, patients in this study required repeat implantation and were unable to be maintained on DEX implant long term due to development of adverse effects or progression of disease. Eventually, it was necessary to transition to systemic immunosuppressive therapy in all patients. Keywords: birdshot chorioretinopathy, dexamethasone implant, inflammation, uveitis 
Obstruction (Also Known as Occlusion or Blockage) of the Ex-PRESS Miniature Glaucoma Device
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