1,488 research outputs found
An innovative approach to simulate thrombosis with smoothed particle hydrodynamics
No full textLa trombosi è una patologia che porta alla formazione di coaguli, che possono provocare ostruzioni arteriose e, infine, migrano attraverso il sistema cardiocircolatorio causando infarto, ictus o embolia polmonare. Il processo è abbastanza complesso ed il suo meccanismo non è ancora chiaro, essendo il risultato dell’interazione tra diversi fattori, compresa l'attivazione e l'aggregazione piastrinica, le reazioni chimiche e l'emodinamica.È fondamentale considerare e ridurre al minimo la formazione di trombi nella progettazione e realizzazione di organi artificiali, come valvole cardiache artificiali o protesi. Lo studio dell'emodinamica può fornire un supporto efficace per identificare e prevenire il rischio di trombosi.A causa della mancanza di soluzioni analitiche adeguate e della complessità degli studi sperimentali, la ricerca evolve sempre più verso l’utilizzo delle simulazioni numeriche Questa tesi mira a modellare la formazione, la crescita e l'evoluzione del trombo mediante il metodo numerico accoppiato Smoothed Particle Hydrodynamics (SPH) usando un modello di interazione fluido-struttura (FSI). Il modello proposto descrive le principali fasi della cascata coagulativa attraverso l'equilibrio di quattro specie biochimiche e tre tipologie di piastrine. Le particelle SPH possono passare dalla fase fluida a quella solida se sono soddisfatte delle specifiche condizioni biochimiche e fisiche. L'accoppiamento fluido-solido è modellato introducendo legami elastici tra le particelle solide senza nessuna interfaccia. Per raggiungere questo obiettivo, in primo luogo il modello viene validato confrontando i risultati numerici con i dati sperimentali disponibili in letteratura, in secondo luogo, il nuovo codice numerico è applicato per descrivere la trombosi in appendice atriale in caso di fibrillazione o come trombosi indotta in aneurismi cerebrali.Thrombosis is a pathology leading to the formation of clots, that can result in arterial obstructions and, eventually, migrate through the cardiocirculatory system causing heart attack, stroke or pulmonary embolism. The process is complex and its mechanism is still unclear, being the result of the interaction between various factors, including platelet activation and aggregation, chemical reactions, and hemodynamics.It is crucial to consider and minimise thrombosis in the design and implementation of artificial organs, such as artificial heart valves, and vascular prostheses. The study of hemodynamics can provide effective support to identify and prevent the risk of thrombosis.Due to the lack of adequate analytical solutions and the complexity of experimental studies, research increasingly evolves towards the use of computational methods.This thesis aims at modelling the formation, growth and evolution of thrombus by means of a Smoothed Particle Hydrodynamics (SPH) numerical method coupled with a fluid-structure interaction (FSI) model. The proposed model describes the main phases of the coagulative cascade through the balance of four biochemical species and three types of platelets. SPH particles can switch from fluid to solid phase whenspecific biochemical and physical conditions are satisfied. Fluid-solid coupling is modelled by introducing elastic binds between solid particles, without requiring detention and management of the interface between the two media.In order to reach this goal, firstly the model is validated by comparing the numerical prediction with experimental data available in the literature, secondly, it is applied to describe thrombosis formation due to relevant pathologies such as atrial fibrillation and cerebral aneurysms where the insertion of flow diverter creates thrombogenic stasis zone
David Audretsch: A Source of Inspiration, a Co-author, and a Friend
No full textIn this chapter, Enrico Santarelli discusses the profound impact that David had on his career. Beginning with a conference in Budapest, Santarelli and David bocame close friends and colleagues. They went on to collaborate on many papers and projects, several of which Santarelli highlights below
Dialogo con Enrico Palandri
No full textA conversation with Enrico Palandri aimed at contextualizing his work as an author
Predictive Stadium Attendance Using Machine Leaning: A Case Study in Italian Football
No full textFootball is one of the most widely followed sports in Italy, and football clubs have now become fully-fledged businesses. In this context, it is of utmost importance to be able to predict match attendance. In this work, we propose a two-phase framework. In the first phase, through a survey containing a conjoint analysis, we will be able to identify fan preferences related to certain match attributes, such as weather, start time, and the day of the week on which the game is played. From the responses we gather, we will create a variable called “utility”, which is then included in
the second phase, represented by the development of ML models with the aim of predicting stadium attendance. We have evaluated this approach in collaboration with an important Italian football Team playing in the first division, using historical data for the training and testing phase. Moreover, we have also applied the proposed methodology to a match of the current season (2023-24). Generally, we can say that the proposed framework performs quite well, allowing us to predict stadium attendance in advance
Enrico Cattaneo : Fotografare un'idea
No full textOltre ad aver raccontato l’arte e gli artisti del secondo Novecento attraverso la documentazione di cinquant’anni di mostre, studi e grandi manifestazioni pubbliche in Italia, Enrico Cattaneo (Milano, 1933-2019) ha sviluppato una personalissima ricerca visuale sui modi, i soggetti e i materiali della fotografia.
Questi due aspetti della sua attività, inseparabili fra loro come le due facce di una medaglia, si ricompongono nella fisionomia unitaria di un autore capace di mettere in questione i presupposti tecnici e concettuali del linguaggio fotografico.
Come lui stesso ha scritto: “L’opera d’arte contemporanea è spesso una cosa più un’idea... Difficile fotografare un’idea”.In addition to having chronicled art and artists of the second half of the 20th century by documenting fifty years of exhibitions, art research, and major public events in Italy, Enrico Cattaneo (Milan, 1933–2019) developed a highly personal visual investigation on the modes, languages, and materials of photography.
These two facets of his activity, indissolubly linked like the two sides of a coin, are recomposed in the overall profile of an author capable of questioning the technical and conceptual foundations of photography.
As he himself has written: ‘The contemporary work of art is often made up of a tangible thing and an idea ... It is difficult to capture an idea on film.
Paolo Enrico Arias in Abruzzo
No full textThe author emphasizes P.E.Arias' contribution to archaeological researches in the Abruzzi, thanks to the Pisan Archaeological Mission at Collelongo (AQ)
Sade : opus contra theatrum
No full textDepuis 1999, date à laquelle il annonce son intention d’entamer un cycle de création ayant pour base les oeuvres du marquis de Sade, Enrico Frattaroli a créé 5 spectacles formant un ensemble intitulé Sade convivium. Dans le document qu’il a préparé pour L’Annuaire théâtral, il explique la démarche artistique singulière par laquelle il utilise la matière sadienne tout en évitant de mettre en scène à la fois son théâtre et son oeuvre romanesque.Since 1999, the date he announced his intention to write a cycle of plays based on the works of the Marquis de Sade, Enrico Frattaroli has created five works in this ensemble that bears the title The Sade convivium. In the document he has prepared for L’Annuaire théâtral, he explains his unique approach whereby he uses the works of Sade as a creative material rather than attempting to produce the plays or the novels of the French author
Una mirada desde la memoria a dos experiencias de teatros políticos locales. : En torno de los escritos dramáticos libertarios de Enrico Giulio
No full textAfter considering the political background of Argentina during the three first decades of the xxth century, the author analyzes a very interesting example of anarchist theatre: Falsas promesas, one of the dramatic texts of Enrico Giulio, ceramist worker and libertarian poet.Después de considerar el trasfondo político argentino de las tres primeras décadas del siglo XX, el autor analiza una interesante ejemplo del teatro anarquista: Falsas promesas, uno de los textos dramáticos de Enrico Giulio, obrero ceramista y poeta libertario
The Schreber case: the discret charm of the paranoic solution
No full textThe author revisits Schreber’s Case considering the scientific and historical back ground context and expecially the development of the first group of Freud’s followers. The concept of inconscious homosexuality is examinated and compared to rejection of feminine. Moreover delirium is considered an attempt at making self-containing. In conclusion, the author suggests some considerations about the connection between paranoic functioning and psychoanalytical group functioning
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