2,357 research outputs found
A web-based screening tool for near-port air quality assessments
No full textAuthor(s): Isakov, Vlad; Barzyk, Timothy M; Smith, Elizabeth R; Arunachalam, Saravanan; Naess, Brian; Venkatram, Akul
Catholic Comments Podcast.
No full textFr. Brian McCoy, S.J. discusses his ministry to aboriginal Australians.
McCoy is an anthropologist and a scholar in residence at Creighton University this semester. He is also the author of the book, “Holding Men,” which studies health issues among aboriginal men
Botulinum neurotoxin for head and neck disorders/ [edited by] Andrew Blitzer, Brian E. Benson, Diana N. Kirke
No full textIncludes bibliographical references and index"Senior author Dr. Andrew Blitzer is an internationally renowned pioneer on the use of botulinum neurotoxin for functional disorders, with unparalleled expertise on this topic. Joined by co-editors Brian Benson and Diana Kirke, with multidisciplinary contributors, Botulinum Neurotoxin for Head and Neck Disorders Second Edition fills a gap in the medical literature. The unique textbook focuses on the use of botulinum neurotoxins for functional disorders of the head and neck, though with some aesthetic indications. The second edition reflects the latest advances and understanding of existing and emerging applications for botulinum neurotoxins, including new treatment paradigms, revised pharmacology, and an updated review of the literature in all chapters. Twenty superbly illustrated chapters cover the management of hyperfunctional, pain, and hypersecretory syndromes of the head and neck. Hyperfunctional motor disorders are discussed in chapters focused on blepharospasm, facial dystonia, Meige syndrome, oromandibular dystonia, spasmodic dysphonia (laryngeal dystonia), and cervical dystonia. Specific treatment approaches for pain are addressed in chapters on migraine and chronic daily tension headaches, temporomandibular disorders, and trigeminal neuralgia. The treatment of autonomic nervous system disorders is covered in chapters dedicated to Frey syndrome, facial hyperhydrosis, and sialorrhea"--Pharmacology of Botulinum Neurotoxins / Muna I. Bitar, Nikita Kohli, Maya Samman, and Andrew Blitzer -- Botulinum Neurotoxin for Blepharospasm / Amit Patel, Andrew Blitzer, and Boris L. Bentsianov -- Botulinum Neurotoxin for Facial Dystonia / Scott M. Rickert, Amy P. Wu, and Andrew Blitzer Botulinum -- Neurotoxin for Meige Syndrome / Niv Mor and Andrew Blitzer -- Botulinum Neurotoxin for Oromandibular Dystonia / Daniel Novakovic and Ajay E. Chitkara -- Botulinum Neurotoxin for Spasmodic Dysphonia / Phillip C. Song, Lucian Sulica, and Andrew Blitzer -- Botulinum Neurotoxin for Cervical Dystonia / Tanya K. Meyer, Joel Guss, and Ronda E. Alexander -- Botulinum Neurotoxin for Hemifacial Spasm and Facial Synkinesis / Lesley French Childs, Daniel Novakovic, and Scott R. Gibbs -- Botulinum Neurotoxin for Hyperfunctional Facial Lines / Brian E. Benson, Diana N. Kirke, and Andrew Blitzer -- Botulinum Neurotoxin for Upper and Lower Esophageal Spasm / Nwanmegha Young and Brian E. Benson -- Botulinum Neurotoxin for Palatal Myoclonus / Ajay E. Chitkara, Catherine F. Sinclair, and Daniel Novakovic -- Botulinum Neurotoxin for Temporomandibular Disorders, Masseteric Hypertrophy, and Cosmetic Masseter Reduction / Michael Z. Lerner and Andrew Blitzer -- Botulinum Neurotoxin Therapy in the Laryngopharynx / Craig H. Zalvan, Phillip C. Song, Nwanmegha Young, and Andrew Blitzer -- Botulinum Neurotoxin for Migraine / Rachel Kaye, Jerome Schwartz, Brian E. Benson, and William J. Binder -- Botulinum Neurotoxin for Chronic Tension Headache / Nwanmegha Young and Brian E. Benson -- Botulinum Neurotoxin for Trigeminal Neuralgia / Elizabeth Guardiani, Andrew Blitzer, Lesley French Childs, and Ronda E. Alexander -- Botulinum Neurotoxin for Frey's Syndrome / Rachel Kaye, Andrew Blitzer, and Brian E. Benson -- Botulinum Neurotoxin for Facial Hyperhidrosis / Diana N. Kirke, Daniel Novakovic, and Andrew Blitzer -- Botulinum Neurotoxin for Sialorrhea / Brianna K. Crawley, Scott M. Rickert, Senja Tomovic, and Andrew Blitzer -- Botulinum Neurotoxin for Radiation-Induced Spasm and Pain / Diana N. Kirke, Brian E. Benson, and Tanya K. Meyer1 online resourc
Supernova shrapnel: nearby supernovae and dust transport in the ISM
No full textThe last 2 decades have seen the proposal, detection, and confirmation of live ^60Fe radioisotopes from an extra-solar source on Earth, showing an event outside the Solar System directly delivered material to the Earth since its formation. This work examines the possible sources for the ^60Fe and models the passage of the material from its source through the Solar System to the ocean floor. We consider the production and deposition on Earth of isotopes with half-lives in the range 10^5 to 10^8 years that might provide signatures of nearby stellar explosions, extending previous analyses of Core-Collapse Supernovae (CCSNe) to include Electron-Capture Supernovae (ECSNe), Super-Asymptotic Giant Branch (SAGBs) stars, Thermonuclear/Type Ia Supernovae (TNSNe), and Kilonovae/Neutron Star Mergers (KNe). We revisit previous estimates of the ^60Fe and ^26Al signatures, and extend these estimates to include ^244Pu and ^53Mn. We show that (i) the ^60Fe yield rules out the TNSN and KN interpretations, (ii) the ^60Fe signals highly constrain a SAGB interpretation but do not completely them rule out, (iii) are consistent with a CCSN origin, and (iv) are highly compatible with an ECSN interpretation.
We also examine various influences on the path of interstellar dust carrying ^60Fe from a SN through the Heliosphere, with the aim of estimating the final global distribution on the ocean floor. We study the influences of magnetic fields, angle of arrival, wind and ocean cycling of SN material on the concentrations at different locations. We find that the passage of SN material through the mesosphere/lower thermosphere (MLT) is the greatest influence on the final global distribution, with ocean cycling causing lesser alteration as the SN material sinks to the ocean floor. SN distance estimates in previous works that assumed a uniform distribution are a good approximation. Including the effects on surface distributions, we estimate a distance of 46^(+10)_(-6) pc for an ECSN progenitor. We note that the SN dust retains directional information to within 1^(circ) through its arrival in the inner Solar System, so that SN debris deposition on inert bodies such as the Moon will be anisotropic, and thus could in principle be used to infer directional information.
Lastly, we examine the various influences on the path of dust within a SN remnant (SNR) to determine when/if the dust decouples from the plasma, how much it is sputtered, and where within the ejecta the dust is located. We find that the inclusion of Rayleigh-Taylor (R-T) instabilities are important in studying dust survival as R-T instabilities influence the location of the SN's reverse shock. We also find the presence of a magnetic field within the shocked ISM material will limit the passage of SN dust grains reflecting them or trapping within the heart of the SNR.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2018-08-01The student, Brian Fry, accepted the attached license on 2016-07-04 at 15:08.The student, Brian Fry, submitted this Dissertation for approval on 2016-07-04 at 15:23.This Dissertation was approved for publication on 2016-07-08 at 16:47.DSpace SAF Submission Ingestion Package generated from Vireo submission #9750 on 2016-11-10 at 12:24:50Made available in DSpace on 2016-11-10T18:39:16Z (GMT). No. of bitstreams: 2
FRY-DISSERTATION-2016.pdf: 10656279 bytes, checksum: 4e1be1f79a71e1417f54d190dc1ba4e3 (MD5)
LICENSE.txt: 4206 bytes, checksum: 2fa157ab76c1e3bf97094664353e401f (MD5)
Previous issue date: 2016-07-08Embargo set by: Seth Robbins for item 95449
Lift date: 2018-11-10T18:39:22Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 95449
Lift date: 2018-11-10T18:43:22Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 95449 on 2018-11-11T10:15:45Z
Give growth and macroeconomic stability in Russia a chance - harden budgets by eliminating nonpayments
No full textThe authors analyze the links between Russia's disappointing growth performance in the second half of the 1990s, its costly and unsuccessful stabilization, the macroeconomic meltdown of 1998, and the spectacular rise of non-payments. Non-payments flourished in an environment of fundamental inconsistency between a macroeconomic policy geared at sharp disinflation, and a microeconomic policy of bailing enterprises out through soft budget constraints. Heavy untargeted implicit subsidies flowing through the non-payments system (amounting to 10 percent of GDP annually) have stifled growth, contributed to the August 1998 meltdown, through their impact on public debt, and have made at best a questionable contribution to equity. Dismantling this system must be a top priority, along with promoting enterprise restructuring and growth (by hardening budget constraints) and medium-term macroeconomic stability (by reducing the size of subsidies). Getting the government out of the non-payments system means settling all appropriately controlled budgetary expenditures on time, and in cash, and eschewing spending arrears, thereby setting an example for enterprises, and laying the groundwork for eliminating tax offsets at all levels of government, and insisting on cash tax payments. To stop energy-related subsidies, would require not only that the government pay its own energy bills on time, and in cash, but also that the energy monopolies be empowered to disconnect non-paying clients. This will enable the government to insist that the energy monopolies in turn pay their own taxes in full, and on time.Banks&Banking Reform,Public Sector Economics&Finance,Economic Theory&Research,Payment Systems&Infrastructure,Environmental Economics&Policies,Banks&Banking Reform,Environmental Economics&Policies,Municipal Financial Management,Public Sector Economics&Finance,Economic Theory&Research
Author Correction: Dental anomaly detection using intraoral photos via deep learning (Scientific Reports, (2022), 12, 1, (11577), 10.1038/s41598-022-15788-1)
No full textIn the original version of this Article Ronilo Ragodos, Tong Wang and Brian J. Howe were omitted as equally contributing authors. Tong Wang was omitted as an additional corresponding author. Correspondence and requests for materials should also be addressed to [email protected]. In addition, the Author Contributions section in this Article was incorrect.Fil: Ragodos, Ronilo. University of Iowa; Estados UnidosFil: Wang, Tong. University of Iowa; Estados UnidosFil: Padilla, Carmencita. University of the Philippines; FilipinasFil: Hecht, Jacqueline T.. University of Texas; Estados UnidosFil: Poletta, Fernando Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Orioli, Ieda Maria. Universidade Federal do Rio de Janeiro; BrasilFil: Buxó, Carmen J.. Universidad de Puerto Rico; Puerto RicoFil: Butali, Azeez. University of Iowa; Estados UnidosFil: Valencia Ramirez, Consuelo. Clinica Noel; ColombiaFil: Restrepo Muñeton, Claudia. Clinica Noel; ColombiaFil: Wehby, George. University of Iowa; Estados UnidosFil: Weinberg, Seth M.. University of Pittsburgh; Estados Unidos. University of Pittsburgh at Johnstown; Estados UnidosFil: Marazita, Mary L.. University of Pittsburgh at Johnstown; Estados Unidos. University of Pittsburgh; Estados UnidosFil: Moreno Uribe, Lina M.. University of Iowa; Estados UnidosFil: Howe, Brian J.. University of Iowa; Estados Unido
The nature of ammonium ion disorder in ammonium tetrafluoroaluminate, NHAlF
No full textPT: J; CR: BERRY LG, 1976, POWDER DIFFRACTION F BRADE RM, 1971, J PHYS C SOLID STATE, V4, P876 BULOU A, 1982, MATER RES BULL, V17, P391 CHIHARA H, 1983, PHYS CHEM, V87, P188 COUZI M, 1983, PHYS CHEM, V87, P232 COUZI M, 1985, J PHYS-PARIS, V46, P435 DAGHORN Y, 1985, J PHYS C SOLID STATE, V18, P383 FOURQUET JL, 1979, REV CHIM MINER, V16, P490 GIRDHAR HL, 1968, J CHEM ENG DATA, V13, P239 KNOP O, 1985, CAN J CHEM, V63, P516 KOBAYASHI K, 1985, SOLID STATE COMMUN, V53, P719 LAUNAY JM, 1984, MATER RES SOC S P, V21, P167 LEBLE A, 1982, PHYS STATUS SOLIDI, V69, P249 MACKOWIAK M, 1984, MAT RES B, V19, P249 NYQUIST RA, 1971, INFRARED SPECTRA INO PARSONAGE NG, 1978, DISORDER CRYSTALS SHINN DB, 1966, INORG CHEM, V5, P1927 SIMON F, 1922, ANN PHYS-BERLIN, V68, P241 VANOORT MJM, J CHEM SOC F1 WAGNER EL, 1950, J CHEM PHYS, V18, P296 WEIR RD, 1980, J CHEM PHYS, V73, P1386 WESTRUM EF, 1969, J CHEM PHYS, V50, P5083 WHITE MA, UNPUB WHITE MA, 1981, J CHEM THERMODYN, V13, P283 WHITE MA, 1984, THERMOCHIM ACTA, V74, P55; NR: 25; TC: 9; J9: J CHEM PHYS; PG: 5; GA: AUR04Source type: Electronic(1
A calorimetric investigation of polymorphism in a layered perovskite: KAlF4
No full textPT: J; CR: BERRY LG, 1976, POWDER DIFFRACTION F BROOKER M, 1985, UNPUB BROSSET C, 1937, Z ANORG ALLG CHEM, V235, P139 BULOU A, 1982, J PHYS C SOLID STATE, V15, P183 BULOU A, 1982, MATER RES BULL, V17, P391 COUZI M, 1985, J PHYS-PARIS, V46, P435 LAUNAY JM, 1984, MATER RES SOC S P, V21, P167 LAUNAY JM, 1985, J PHYS-PARIS, V46, P771 MILLIER B, 1985, J CHEM EDUC, V62, P64 OGASAHARA K, 1979, CHEM PHYS LETT, V68, P457 SCHOONMAN J, 1976, J SOLID STATE CHEM, V16, P413 VANOORT MJM, 1985, J CHEM SOC F1, V81, P3059 WHITE MA, UNPUB WHITE MA, 1984, THERMOCHIM ACTA, V74, P55 WHITE MA, 1985, J CHEM PHYS, V83, P5844; NR: 15; TC: 2; J9: J CHEM THERMODYN; PG: 8; GA: C5290Source type: Electronic(1
Tissue engineering of a tracheal substitute
No full textLectin histochemistry and scanning electron microscopy (SEM) was used to assess the growth and characterise the differentiation of human respiratory epithelial cells (REC) cultured on two biomaterial scaffolds. The first scaffold, based on a hyaluronic acid derivative, was observed to be non-adhesive for REC. This lack of adhesion was found to be unrelated to the presence of the hyaluronic acid binding domain on the surface of isolated REC. The other scaffold, consisting of equine collagen, was observed to encourage REC spreading and adhesion. Positive Ulex Europaeus agglutinin (UEA) lectin staining of this preparation indicated the presence of ciliated REC on the scaffold surface. However, the marked decrease in peanut agglutinin (PNA) positive staining, relative to that of control cultures and native tissue, indicates a dedifferentiation of the secretory cells in monolayer. SEM analysis of REC cultured on the collagen scaffold confirmed the presence of ciliated cells thereby validating the UEA positive staining. The presence of both established and developing cilia was also verified. This indicates that collagen biomaterials are appropriate for the tissue engineering of REC. Furthermore, that UEA and PNA staining is a useful tool in the characterisation of cells cultured on biomaterials, therefore helpful in identifying biomaterials that are suitable for specific tissue engineering purposes.
The culture of REC at an air liquid interface (ALI) was investigated. Both conventional ALI inserts and the Biofleece scaffold were used. The cells grown the on conventional inserts became multilayered and showed some degree of ciliation after the period of ten days. The cells grown on the Biofleece scaffold became necrotic and died due to nutrient deprivation. The use of ALI culture techniques on scaffold materials needs to be adjusted to allow for sufficient nutrient supply to the cells.
The Biofleece scaffold was found to be suitable for the tissue engineering of cartilage in vitro. Constructs with a cartilage-like morphology were generated with the scaffold after two weeks in culture. The tissue-engineered cartilage was found to contain a higher number of cells and less extracellular matrix (ECM) than the native tissue controls. Suction seeding techniques were used to improve the distribution of cells within the scaffold and thereby increase the overall efficiency of cartilage tissue engineering within the scaffold. Alcian blue (AB) and Papanicolau (PN) stains of the tissue engineered cartilage described two distinct regions within the constructs, namely the developed cartilage-like region and the developing region. The latter is thought to be areas in which the cartilage cells are yet to fully remodel the scaffold material and deposit their own “native” ECM. However, the Biofleece scaffold material was observed to loose 40-50% of its initial volume during the tissue engineering process over a period of two weeks. Thus the degradation of the Biofleece scaffold exceeds the rate of maturation of the cartilage tissue within the scaffold. This rapid biodegradation is most likely a result of matrixmetalloproteinase (MMP), in particular collagenase, production by the maturing chondrocytes. This reduction in size means that the Biofleece scaffold is not an appropriate material for the tissue engineering of a trachea. The optimal biomaterial for the tissue engineering of a trachea would degrade at a rate equal too, or slower than, the time taken for the cells within the scaffold to mature into functional tissue.
The co-culture of REC and chondrocytes was achieved through the use of matrigel as a basement membrane replacement (note that direct growth of REC on cartilage tissue has been observed to be difficult). The co-cultured constructs were not stable because the Biofleece scaffold degrades at a high rate in the presence of both cell types. The constructs were observed to shrink to approximately 35-30% of the original dimensions in a period of 3-7 days. The reason for this accelerated degradation is not known but is most likely the result of severe MMP production by the two cell types when in combination.
It was concluded that the characterisation procedures used in this study (histochemical staining, fluorescent staining and scanning electron microscopy) for both REC and chondrocyte tissue engineered constructs are appropriate for this and further studies. The chondrocyte seeding methodologies in particular are a useful tool for tissue engineering. This study succeeds in many ways to investigate the tissue engineering of a tracheal substitute by detailing how REC and chondrocytes can be cultured on biomaterials and assessed for tissue development. However, the study does not deliver such a viable substitute as an end product. The primary reason for this outcome is the rapid degradation of the Biofleece scaffold materialLectin Histochemie und Elektronenmikroskopie wurden benutzt, um das Wachstum von humanen respiratorischen Epithelzellen (RECs), welche auf zwei Biomaterialien kultiviert wurden, festzusetzen und ihren Differenzierungsgrad zu bestimmen. Das erste Trägermaterial, welches auf einem Hyaluronsäurederivat basiert, ließ keine Anheftung der RECs zu. Diese fehlende Anheftung ließ sich jedoch nicht zurückführen auf das Vorhandensein der Hyaluronsäure bindenden Domaine auf der Oberfläche isolierter RECs. Das andere Trägermaterial, aus Pferdekollagen hergestellt, zeigte dagegen eine verstärkte Teilungsaktivität und Anheftung der REC. Die positive Ulex Europaeus Agglutinin (UEA) Lectin Färbung dieser Proben ließ die Anwesenheit von mit Zilien versehenen RECs auf der Trägerstoffoberfläche vermuten. Darüber hinaus weist das im Vergleich zu Kontrollkulturen und nativem Gewebe deutliche Nachlassen der positiven Peanut Agglutinin–Färbereaktion auf eine Dedifferenzierung der sekretorischen Zellen in der Monolayer-Kultur hin. Die rasterelektronenmikroskopische Untersuchung der auf dem Kollagenbiomaterial kultivierten RECs bestätigte das Auftreten von Zellen mit Zilien und damit auch die Aussagekräftigkeit der positiven UEA–Färbung. Dies zeigt somit, dass Biomaterialien aus Kollagen für das Tissue Engineering von RECs geeignet sind und dass sowohl die UEA–als auch die PNA–Färbung geeignete Methoden zur Charakterisierung von Zellen darstellen, die auf Biomaterialien kultiviert wurden. Somit helfen sie bei der Identifizierung von Biomaterialien für bestimmte Einsatzgebiete im Tissue Engineering.
Des weiteren wurde die Kultivierung von RECs auf einem Air liquid interface (ALI) untersucht, wobei sowohl der konventionelle ALI–Einsatz als auch das Biovliesmaterial zum Einsatz kamen. Dabei wuchsen die Zellen auf dem konventionellen Einsatz in Multilayern und zeigten nach einem Zeitraum von 10 Tagen einen bestimmten Anteil an Ziliierung. Die Zellen auf dem Biovlies dagegen wurden nekrotisch und gingen schließlich an Nahrungsmangel ein. Deshalb muss der Einsatz von ALI–Kulturtechniken bei Trägermaterialien dementsprechend modifiziert werden, dass eine ausreichende Versorgung der Zellen mit Nährstoffen gewährleistet ist.
Für das in vitro–Tissue Engineering von Knorpel erwies sich das Biovlies jedoch als geeignet. Mit ihm konnten nach zwei Wochen Kulturzeit Konstrukte mit einer knorpelähnlichen Morphologie erzeugt werden. Dabei zeigte sich, dass der Tissue Engineering–Knorpel eine höhere Zellzahl bei reduzierter extrazellulärer Matrix (ECM) aufwies als vergleichbares natives Kontrollgewebe. Dabei wurden Saugtechniken benutzt, um die Verteilung der Zellen im Trägerstoff zu verbessern. Die Alzian – Blau – Färbung (AB) und Papanicolau – Färbung (PN) zeigten bei dem Tissue Engineering–Knorpel zwei unterschiedliche Regionen innerhalb des Konstrukts, nämlich eine knorpelähnliche bereits entwickelte Region und eine sich entwickelnde Region. Bei letzterer dürfte es sich wohl um Gebiete handeln, in denen Zellen noch im Begriff sind, den Trägerstoff vollends umzubauen und ihre eigene „native“ ECM abzulagern. Nichtsdestoweniger büßte das Biovlies während des Tissue Engineering Prozesses über einen Zeitraum von zwei Wochen annähernd 40-50 % seines anfänglichen Volumens ein. Somit übersteigt das Ausmaß der Degradation des Biovlieses das des Heranreifens von Knorpelgewebe in dem Trägermaterial. Diese schnelle Biodegradation ist am ehesten das Ergebnis der Aktivität von Matrixmetalloproteinasen (MMP), insbesondere der Kollagenase, welche von reifenden Chondrozyten produziert wird. Diese Schrumpfung bedeutet also, dass das Biovlies kein geeignetes Material für das Tissue Engineering der Trachea darstellt. Denn ein optimales Biomaterial für das Tissue Engineering der Trachea sollte sich innerhalb derselben Zeit bzw. über einen längeren Zeitraum hinweg abbauen, als innerhalb desjenigen, den die sich in dem Trägermaterial befindlichen Zellen benötigen, um zu funktionalem Gewebe heranzureifen.
Durch den Einsatz von Matrigel als Ersatz für die Basalmembran konnte eine Kokultur aus RECs und Chondrozyten etabliert werden (wobei anzumerken ist, dass sich direktes Wachstum von RECs auf Knorpelgewebe als problematisch erweist). Die Konstrukte aus Kokulturen waren nicht stabil, da das Biovlies in Anwesenheit beider Zelltypen hochgradig abgebaut wird. Innerhalb von 3–7 Tagen schrumpften die Konstrukte auf ca. 35–50 % ihrer Ausgangsgröße zusammen. Der Grund für diesen beschleunigten Abbau ist unbekannt, jedoch ist am ehesten eine ausgeprägte Produktion von MMP durch die beiden Zellarten anzunehmen, sobald diese in Kombination vorliegen.
Insgesamt lässt sich sagen, dass die Methoden zur Zell- und Gewebecharakterisierung, welche in dieser Studie benutzt wurden (histochemische Färbungen, Fluoreszenzfärbung und Elektronenmikroskopie) sowohl für mit RECs als auch mit Chondrozyten hergestellte Konstrukte für die vorliegende Arbeit als auch zukünftige Studien als geeignet anzusehen sind. Diese Studie hat in vielerlei Hinsicht erfolgreich das Tissue Engineering einer Luftröhre untersuchen können, indem sie im Detail aufzeigt, wie RECs und Chondrozyten auf Biomaterialien kultiviert und für das Tissue Engineering eingesetzt werden können. Trotzdem kann diese Arbeit kein einsetzbares Ersatzmaterial als Endprodukt liefern. Der Hauptgrund für dieses Ergebnis ist in erster Linie in dem schnellen Abbau des Biovlieses als Trägermaterial zu sehen
Developing Primary Care: The Contribution of Primary Care Research Networks
No full textThe performance of Canada's primary care sector remains lacklustre relative to other wealthy industrialized countries, and it has been suggested that a lack of investment in research and evaluation may be a cause. One approach to improving and sustaining primary care research is through research networks. Over the past few years, significant investments have begun to be made in developing primary care networks in Canada. While Canadian experience in this area is relatively new, in the United Kingdom primary care research networks were first established in the 1980s. Initially developed at a local level, these have more recently been incorporated into large-scale national networks. This paper reviews the UK experience and highlights potential lessons for the development of networks in Canada
- …
