1,721,110 research outputs found
Genotyping of Pooled Microsatellite Markers by Combinatorial Optimization Techniques
AbstractAn important everyday task for geneticists and molecular biologists is that of isolating and analyzing some particular DNA regions (markers), each drawn from a limited and known set of possible values (alleles). This procedure is called genotyping and is based on DNA amplification and size separation. In order to increase the throughput of genotyping, recently a new experiment has been proposed which tries to analyze many different markers of similar size at once. We study the mathematical problem corresponding to this model and give a branch-and-bound algorithm for its solution. We show that by using the techniques described in this paper, genotyping of pooled markers can be computed effectively, thus potentially achieving a considerable reduction in time and expense
M of a kind: A Multivariate Approach at Pairs Trading
Pairs trading is a popular trading strategy that tries to take advantage of market inefficiencies in order to obtain profit. Such approach, on its classical formulation, uses information of only two stocks (a stock and its pairs) in the formation of the trading signals. The objective of this paper is to suggest a multivariate version of pairs trading, which will try to create an artificial pair for a particular stock based on the information of m assets, instead of just one. The performance of three different versions of the multivariate approach was assessed for the Brazilian financial market using daily data from 2000 to 2006 for 57 assets. Considering realistic transaction costs, the analysis of performance was conducted with the calculation of raw and excessive returns, beta and alpha calculation, and the use of bootstrap methods for comparing performance indicators against portfolios build with random trading signals. The main conclusion of the paper is that the proposed version was able to beat the benchmark returns and random portfolios for the majority of the parameters. The performance is also found superior to the classic version of the strategy, Perlin (2006b). Another information derived from the research is that the proposed strategy picks up volatility from the data, that is, the annualized standard deviations of the returns are quite high. But, such event is “paid” by high positive returns at the long and short positions. This result is also supported by the positive annualized sharpe ratios presented by the strategy. Regarding systematic risk, the results showed that the proposed strategy does have a statistically significant beta, but it isn’t high in value, meaning that the relationship between return and risk for the trading rules is still attractive.pairs trading, asset allocation, quantitative strategy
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Evaluation of pairs trading strategy at the Brazilian financial market
Pairs trading is a popular trading strategy that tries to take advantage of market inefficiencies in order to obtain profit. The idea is simple: find two stocks that move together and take long/short positions when they diverge abnormally, hoping that the prices will converge in the future. From the academic point of view of weak market efficiency theory, pairs trading strategy shouldn’t present positive performance since, according to it, the actual price of a stock reflects its past trading data, including historical prices. This leaves us with a question, does pairs trading strategy presents positive performance for the Brazilian market? The main objective of this research is to verify the performance and risk of pairs trading in the Brazilian financial market for different frequencies of the database, daily, weekly and monthly prices for the same time period. The main conclusion of this simulation is that pairs trading strategy was a profitable and market neutral strategy at the Brazilian Market. Such profitability was consistent over a region of the strategy’s parameters. The best results were found for the highest frequency (daily), which is an intuitive result.pairs trading, quantitative strategy, asset allocation
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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