169,775 research outputs found
Different approaches to assess the seismic capacity of masonry bridges by non-linear static analysis
No full textA large portion of the existing masonry arch bridges in Italy are still in service in the infrastructure system and are located in a geographical area of high seismic risk. Most of them were built more than 100 years ago taking into account only gravitational loads during the design phase without any seismic analysis. For this reason, a seismic vulnerability assessment has been appointed asmandatory regular activity from the Italian government in order to define the priority of seismic retrofit interventions. In this study, a multi-span slender masonry bridge considered as the most vulnerable typology of masonry bridges to seismic action will be assessed. Then, the results obtained from three different seismic assessment approaches will be discussed and compared. In particular, two approaches based on different FE modeling and the last one built on rigid blocks analysis are considered. Finally, a detailed 3D finite element analysis allowed representing all the collapse mechanisms (global and local) of the bridges are presented. Simplified approaches, even though cannot describe all the collapse mechanisms of the bridges due to seismic action can lead to reliable results
Access to pyrrolo-pyridines by gold-catalyzed hydroarylation of pyrroles tethered to terminal alkynes
No full textIn a simple procedure, the intramolecular hydroarylation of N-propargyl-pyrrole-2-carboxamides was accomplished with the aid of gold(III) catalysis. The reaction led to differently substituted pyrrolo[2,3-c]pyridine and pyrrolo[3,2-c]pyridine derivatives arising either from direct cyclization or from a formal rearrangement of the carboxamide group. Terminal alkynes are essential to achieve bicyclic pyrrolo-fused pyridinones by a 6-exo-dig process, while the presence of a phenyl group at the C–C triple bond promotes the 7-endo-dig cyclization giving pyrrolo-azepines
Numerical Analysis of an FRP-Strengthened Masonry Arch Bridge
No full textHistorical masonry arch bridges are a fundamental part of the road and railway networks in Europe. Very often, due to factors such as lack of maintenance, increase of traffic loads, etc., these structures need interventions in order to guarantee their adequate structural performance. For this reason, an important research effort has been devoted in previous decades to study the behavior of masonry arches and to identify innovative techniques able to increase their ultimate capacity, such as fiber reinforced polymer (FRP) composites. In this paper, the results of an experimental campaign carried out on masonry arches strengthened with one FRP layer applied at the structure intrados are used to calibrate a numerical analysis model. Then, the model is used to predict the contribution that this type of strengthening would have had on the well-known Prestwood Bridge. The numerical results show that the hypothetical intervention of the Prestwood Bridge would imply an increase in the ultimate load of the structure, although it would be significantly lower than that usually obtained for the case of arches tested in laboratory
Transference numbers of aqueous HCl up to 15 mol-kg-1 at 25°C : a systematization and reassessment
No full textIon-transfer parameters of aq. hydrochloric acid over a wide molality range have been re-investigated taking the concurrent solvent-transfer into due account. In this context, the transference nos. for the hydrogen ion τH and for water τw have been detd. from 10-2 to 15 mol-kg-1, together with the corresponding infinite-diln. values τH0×w0, by processing a set of nearly a hundred emf. measurements (some twenty of them new for this work) on HCl concn. cells with transference with both cation-reversible and anion- reversible electrode pairs
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Cities are diverse, complex, and dynamic systems. How can we plan them in a resilient direction?
No full textThe UN-Habitat’s definition of urban resilience refers to “...the measurable ability of any urban system, with its inhabitants, to maintain continuity through all shocks and stresses, while positively adapting and transforming toward sustainability. A resilient city assesses, plans and acts to prepare for and respond to hazards – natural and human-made, sudden and slow-onset, expected and unexpected – in order to protect and enhance people’s lives, secure development gains, foster an investible environment, and drive positive change.”
In this definition we find three key words (or rather three key concepts) that are extremely simple but at the same time particularly meaningful: assess, plan and act. In the belief that developing a resilient and sustainable city requires a roadmap of actions and activities that are both implementable and feasible, yet precise and ambitious in their expected impacts, the paper seeks to explore how we can use the resilience approach as a catalyst for sustainable urban development.
Through this vision cities can be interpreted as ‘evolving places’ formed by an intertwined set of structures resulting from diverse and competing forces, cultural and natural, whose patterns vary in response to the specific context. The paper proposes three ‘meta’-themes to which to refer our design: Integrated Planning, Resilient Infrastructures and Responsive Preparedness.
And so, we can imagine the resilience like a catalyst for sustainable urban development. It ensures development gains are not lost when cities face shocks and urban residents can flourish in a safe environment while addressing major challenges such as climate change and rapid urbanisation
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
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