1,720,958 research outputs found
ENDOSCOPIC REMOVAL OF HYPOPHYSEAL ADENOMAS: A RETROSPECTIVE STUDY
No full textAuthor Keywords:endoscopic; endonasal approach; hypophyseal adenoma; sella turcicaIn this study was assessed the role that the direct endonasal approach with the operating endoscope plays in assisting operations for pituitary adenomas. During a 5-year period, from October 2004 to December 2010 - 42 patients (24 males and 18 females) with hypophyseal adenoma were treated with endoscopic- surgery. Surgery was performed via endonasal trans-sphenoidal approach. Three patients had complications (nasal hemorragia, anosmia, and rhinoliquorrea) in the follow-up period (mean 3 months). No statistical significance was detected between tumor dimensions and complications. On the basis of our experience, it is our opinion that this technique has a low rate of complications, particularly when adequate surgical instruments are used by surgeons who have familiarity with the endoscopic anatomy of the sphenoid sinus
ENDOSCOPIC REMOVAL OF HYPOPHYSEAL ADENOMAS: A RETROSPECTIVE STUDY
No full textIn this study was assessed the role that the direct endonasal approach with the operating endoscope plays in assisting operations for pituitary adenomas. During a 5-year period, from October 2004 to December 2010 - 42 patients (24 males and 18 females) with hypophyseal adenoma were treated with endoscopic- surgery. Surgery was performed via endonasal trans-sphenoidal approach. Three patients had complications (nasal hemorragia, anosmia, and rhinoliquorrea) in the follow-up period (mean 3 months). No statistical significance was detected between tumor dimensions and complications. On the basis of our experience, it is our opinion that this technique has a low rate of complications, particularly when adequate surgical instruments are used by surgeons who have familiarity with the endoscopic anatomy of the sphenoid sinu
Primary pituitary neuroendocrine tumor: Case report and literature review
No full textBackground: Neuroendocrine tumors (NET) originate from the diffuse neuroendocrine system. These can arise in almost every organ of the body, although they are most commonly found in the gastrointestinal tract and respiratory system. The skull base and sellar region are extremely rare sites for neuroendocrine carcinoma. Consequently, in this case, both diagnosis and definition of surgical goals, as well as further treatment strategies were challenging. Case Description: A 65-year-old woman was admitted to our Neurosurgery Department with a rapidly progressive visus reduction, drowsiness, polyuria, and polydipsia. Neuroimaging showed a sellar/suprasellar mass (diameter of 2 cm) with a heterogeneous signal compressing the optic chiasm and extending laterally toward the cavernous sinus. Differential diagnosis based on imaging included pituitary macroadenoma or metastasis. The patient underwent endoscopic endonasal transsphenoidal surgery. A total resection of the mass was impossible because of the infiltration of the optic chiasm and the intraoperative histological diagnosis of malignant epithelial neoplasm. Further histological evaluation revealed that the lesion was a NET with no other primary or metastatic sites detectable. Subsequently, the patient was successfully treated with fractioned stereotactic radiotherapy and polychemotherapy. Four years after the surgery, follow-up magnetic resonance imaging showed stability of the residual disease. Neurologic examination revealed a complete visual recovery. Conclusions: Primary pituitary NET, though rare, should be included in the differential diagnosis of sellar lesions. A multimodality treatment approach is needed. Finally, the present case highlights, that in the case of a pituitary lesion infiltrating the optic chiasm, including NET, the endoscopic endonasal transsphenoidal subtotal resection followed by fractioned stereotactic radiotherapy and chemotherapy may represent an effective and safe choice of treatment
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Congenital Nasal Pyriform Aperture Stenosis: Successful Management of Restenosis After Primary Surgery by Stent Placement
Full text linkCongenital nasal pyriform aperture stenosis (CNPAS) is a rare anomaly causing respiratory distress in newborns. While the primary surgical technique is well established, the timing of the removal of the stents and the management of restenosis remain a matter of debate. We report a case of a female newborn affected by CNPAS with the recurrence of respiratory distress after primary surgery due to the early removal of nasal stents, causing an overgrowth of granulation tissue. This report notes that restenosis was successfully managed by repeating the procedure over a 14-day period, with soft polyvinyl chloride uncuffed tracheal tubes acting as nasal stents
COMPARISON BETWEEN ENDOSCOPIC VS. MICROSCOPIC REMOVAL OF HYPOPHYSEAL ADENOMA: A RETROSPECTIVE STUDY
No full textTo compare endoscopic and neuronavigation-assisted microscopic removal of hypophyseal adenoma in order to detect those variables statistically associated to clinical failures of each technique. Forty-eight patients (27 males and 21 females) with hypophyseal adenoma were treated with microscopy (6 patients) or endoscopic removal (42 patients). Surgery was performed via endonasal trans-sphenoidal approach. Correlations between tumor dimensions (standard and macro-tumor) or surgical techniques (endoscopy vs. microscopic technique) vs. residual tumor, surgical complication (i.e. rhinoliquorrea) and persisting visual deficit, were evaluated. No statistical significance was detected among the studied variables. On the basis of reported data, both techniques are safe if the surgeon is well trained. Neuronavigation applied during endonasal trans-sphenoidal microscopic surgery can precisely define the localization and removal of lesions in the sella region with respect to the margins of important anatomical structures in the neighborhood, decreasing the rate of complication
Comparison between endoscopic vs. microscopic removal of hypophyseal adenoma: a retrospective study
No full textTo compare endoscopic and neuronavigation-assisted microscopic removal of hypophyseal adenoma in order
to detect those variables statistically associated to clinical failures of each technique. Forty-eight patients (27 males and 21 females) with hypophyseal adenoma were treated with microscopy (6 patients) or endoscopic removal (42 patients). Surgery was performed via endonasal trans-sphenoidal approach. Correlations between tumor
dimensions (standard and macro-tumor) or surgical techniques (endoscopy vs. microscopic technique) vs. residual tumor, surgical complication (i.e. rhinoliquorrea) and persisting visual deficit, were evaluated. No statistical
significance was detected among the studied variables. On the basis of reported data, both techniques are safe if the surgeon is well trained. Neuronavigation applied during endonasal trans-sphenoidal microscopic surgery can precisely define the localization and removal of lesions in the sella region with respect to the margins of important anatomical structures in the neighborhood, decreasing the rate of complications
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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