1,721,161 research outputs found
A prospective, randomized, controlled study comparing Gynemesh, a synthetic mesh, and Pelvicol, a biological mesh, in the surgical treatment of recurrent cystocele
Full text linkIntroduzione: questo studio ha avuto come obiettivo quello di valutare l'affidabilità e l'efficacia di due diversi tipi di materiale protesico per la riparazione chirugica del cistocele recidivo: il Gynemesh PS e il Pelvicol .
Materiali e metodi: Questo studio prospettico randomizzato ha riguardato una popolazione di 190 donne. La riparazione del cistocele è stata effettuata con la tecnica del "Tension-free Cystocele Repair".L'analisi statistica è stata condotta mediante : Chi-square test per variabili categoriche, T-test per dati appaiati per le variabili parametriche continue, e Mann-Whitney test per le variabili non parametriche continue.
Risultati: Sono state incluse nello studio 96 pazienti nel gruppo Gynemesh PS® e 94 patienti nel gruppo Pelvicol®. E' stata notata assenza di erosioni a livello della parete vaginale anteriore nel gruppo Pelvicol®, ed una frequenza del 6.3% di erosioni nel gruppo Gynemesh PS (p= 0.02).La percentuale di guarigione oggettiva è stata del 71.9% nel gruppo Gynemesh PS e del 56.4% nel gruppo Pelvicol (p= 0.06). La percentuale di guarigione soggettiva è risultata comparabile nei due gruppi ad eccezione dell'impatto della sfera sessuale, che è risultato migliore nel grupo Pelvicol.
Conclusioni: Ad un follow-up di 24 mesi, abbiamo osservato erosioni vaginali solo nel gruppo Gynemesh. Il risultato anatomico è risultato comparabile nei due gruppi. Abbiamo infine osservato un migliore impatto sulla fase di svuotamento vescicale e sulla sessualità nelle pazienti del gruppo Pelvicol.Introduction and Hypotheses: We compared safety and efficacy of Gynemesh PS and Pelvicol for recurrent cystocele repair.
Methods: 190 patients were randomly assigned to Gynemesh PS or Pelvicol. The technique used was Tension-free Cystocele Repair. The Chi-square test was used to compare categorical variables, the paired t-test for continuous parametric variables, and the Mann-Whitney test for continuous non-parametric variables.
Results: 96 Gynemesh PS patients and 94 Pelvicol patients were included in our study. Mesh erosions occurred in 6.3% of Gynemesh PS patients. No erosions were observed in Pelvicol® patients (p = 0.02). Objective cure was 71.9% for Gynemesh PS and 56.4% for Pelvicol (p=0.06). Subjective cure was comparable in the two groups except for sexuality which was better in the Pelvicol group.
Conclusions: With a follow-up of 24 months, we observed mesh erosions in Gynemesh PS patients only. Anatomical outcome was comparable between groups. A better impact on voiding and sexuality was observed with Pelvicol
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mechanisms Involved in Cardioprotection Induced by Physical Exercise
No full textSignificance: Regular exercise training can reduce myocardial damage caused by acute ischemia/reperfusion (I/R). Exercise can reproduce the phenomenon of ischemic preconditioning, due to the capacity of brief periods of ischemia to reduce myocardial damage caused by acute I/R. In addition, exercise may also activate the multiple kinase cascade responsible for cardioprotection even in the absence of ischemia. Recent Advances: Animal and human studies highlighted the fact that, besides to reduce risk factors related to cardiovascular disease, the beneficial effects of exercise are also due to its ability to induce conditioning of the heart. Exercise behaves as a physiological stress that triggers beneficial adaptive cellular responses, inducing a protective phenotype in the heart. The factors contributing to the exercise-induced heart preconditioning include stimulation of the anti-radical defense system and nitric oxide production, opioids, myokines, and adenosine-5′-triphosphate (ATP) dependent potassium channels. They appear to be also involved in the protective effect exerted by exercise against cardiotoxicity related to chemotherapy. Critical Issues and Future Directions: Although several experimental evidences on the protective effect of exercise have been obtained, the mechanisms underlying this phenomenon have not yet been fully clarified. Further studies are warranted to define precise exercise prescriptions in patients at risk of myocardial infarction or undergoing chemotherapy
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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