1,721,022 research outputs found
Immunohistochemical markers in endometrial cancer
Full text linkIn 2018, 382,069 new cases of uterine cancer were registered worldwide and 89,929 deaths from this cancer were reported [...]
First case of prophylactic salpingectomy with single port access laparoscopy and a new diode laser in a woman with BRCA mutation
Full text linkSpontaneous Conception and Uncomplicated Term Pregnancy after Fertility Preserving Surgery and Chemotherapy in a Young Woman with Embryonal Rhabdomyosarcoma of the Pelvic Wall
No full textOvarian failure after chemotherapy is a challenge for practitioners in infertility. We report a case of uncomplicated term pregnancy in a young woman undergoing surgery and chemotherapy for rhabdomyosarcoma of the pelvic wall. The woman has been followed up for 15 years. She underwent operative laparoscopy and a first course of chemotherapy together with GnRH agonist therapy when she was 22-year-old. An exploratory laparoscopy and a debulking laparotomy were performed after six months because of persistent intraperitoneal disease and were followed by multiple courses of chemotherapy together with GnRH agonist therapy. A laparotomy for adhesiolysis was performed after two years because of mechanical ileus. The woman conceived spontaneously and delivered at term when she was 30-year-old. The long term follow up demonstrated that menstrual pattern, conception and pregnancy were unaffected by surgery and chemotherapy. This case further suggests that attempts to preserve fertility at surgery are mandatory in young women with cancer
Unusual case of adenocarcinoma arising in endometriosis mimicking colorectal cancer in a young woman with a Müllerian anomaly
No full textObjective: To report a case of endometrioid adenocarcinoma that arose in endometriosis mimicking colorectal cancer in a young woman with a Mullerian anomaly.
Design: A case report.
Setting: A university hospital.
Patient(s): A 31-year-old, white nulligravida woman with a history of two previous laparoscopies for infertility
and chronic pelvic pain. A solid rectosigmoid mass adherent to the left pelvic sidewall was found in this patient.
Intervention(s): The patient was subjected to an exploratory laparotomy followed by adjuvant chemotherapy.
Main Outcome Measure(s): Surgical findings and histopathological observations are included in this report.
Result(s): Intraoperative and histologic examinations revealed endometriosis-associated colorectal cancer.
Conclusion(s): Although a rare event, this condition should be considered in the diagnosis of women with a previous history of pelvic endometriosis, Mullerian malformation, abdominal pain, constipation, or rectal bleeding
Uncommon Laparoscopic Findings in a Sexually Immature Agonadal XY Phenotypic Female
No full textA defect of intrauterine development occurring early in male embryogenesis results in a broad range of XY agonadal phenotypes. A 16-year-old girl was referred for evaluation of primary amenorrhea and failure of sexual development. Gynecological examination revealed infantile but otherwise normal female external genitalia with clitoral hypotrophy, absence of hymen, and a tight vaginal introitus. The vagina was 4 cm long and ended in a blind pouch. No masses were detected in inguinal canals or in labia majora. Ultrasonography, computerized tomography, and magnetic resonance imaging failed to demonstrate internal genitalia or gonads. Endocrine evaluation showed elevated plasma concentrations of Follicle Stimulating Hormone and Luteinizing Hormone with undetectable estradiol levels. The kariotype from cultures of peripheral leucocytes was 46, XY. At laparoscopy no uterus or ovarian structures were found. Only two small fibrous oval masses with a thin peduncle were found along each lateral pelvic wall and were excised. Histological examination of these masses revealed that they resembled oviduct tissue. Therefore, the present agonadal XY phenotypic female is the third of such cases that have been reported to have only rudiments of fallopian tubes but is the first of these three cases that has been explored entirely by laparoscopy
First case of prophylactic salpingectomy with single port access laparoscopy and a new diode laser in a women with BRCA mutation.
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Laparoscopic Excision of Posterior Vaginal Fornix in the Treatment of Patients with Deep Endometriosis without Rectum Involvement. Surgical Treatment and Long-Term Follow Up
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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