1,720,967 research outputs found
Rare Tumours of the Lung: A Single Centre Experience
No full textIntroduction: A rare tumour of the lung (RTL) is defined as neoplasm whose incidence is lower than 2% of all pulmonary tumours. Such group includes different benign and malignant lesions with variable occurrence rate. Aim of this study was to retrospectively analyze a single centre surgical experience and com- pare it with the literature.
Patients and Methods: From February 2002 to April 2009 twenty-four patients underwent resection for RTL. Different procedures were utilized, including operative rigid bronchoscopy, wedge resection, lobectomy, pneumonectomy, and bronchoplastic procedures. All patients entered a follow-up program (median 22, range1-79 months).
Results: According to the 2004 WHO classification 6 patients had benign (Group A) and 18 malignant (Group B) RTL. Group A: endobronchial hamartoma (n=1) endobronchial lipoma (n=1), endobronchial fibroepithelial polyp (n=1), benign fibrous hystiocitoma (n=1) and sclerosing hemangioma (n=2). Group B: pulmonary blastoma (B1, n=1), mucoepidermoid carcinoma (B2, n=1), adenoid cystic carcinoma (B3, n=3), inflammatory myofi- broblastic tumour (B4, n=1), pulmonary synovial sarcoma (B5, n=3), dendritic follicular cells sarcoma (B6, n=1), pleomorphic carcinoma (B7, n=2) spindle cell carcinoma (B8, n=2), and carcinosarcoma (B9, n=4). Symptoms were present mostly in centrally- located neoplasms (10/24, n=3 Group A and n=7 Group B). Two patients were lost at follow-up. Three patients with B9 died of the
disease (median 14 months, range 4-15), one B8 immunocompromised patient had progressive disease after 3 months, the remaining are present alive without evidence of disease.
Conclusions: Our results substantially reflect the literature data. A multicentre study would add to the knowledge of this heterogeneous group of tumours
Trattamento chirurgico del diverticolo di Zenker.Confronto tra diverticulectomia e diverticulopessi
No full textImpatto della microalbuminuria nel decorso post operatorio in chirurgia toracica
No full textIMPATTO DELLA MICROALBUMINURIA NEL DECORSO POSTOPERATORIO IN CHIRURGIA TORACICA
Topic: Le nuove tecnologie; Tipo di presentazione: Presentazione orale
Scopo del lavoro
La micro-albuminuria (MA) è manifestazione di un aumento generalizzato della permeabilità vascolare ed un marker precoce e sensibile di disfunzione endoteliale. Alcuni studi hanno attribuito un significato prognostico negativo al brusco aumento di MA dopo trauma, ustioni, pancreatiti, danno da rivascolarizzazione, chirurgia maggiore, ALI e ARDS. Le potenziali implicazioni dell’aumento della MA nel postoperatorio in chirurgia toracica non sono state ancora indagate.
Materiali e Metodi
Studio prospettico osservazionale, a breve termine, condotto su 171 pazienti consecutivi sottoposti in elezione ad intervento di chirurgia toracica. In aggiunta alle valutazioni eseguite di routine, i pazienti sono stati sottoposti pre-operatoriamente, in prima e quarta giornata postoperatoria a determinazione urinaria di microalbumina espressa in valore assoluto (mediante determinazione quantitativa immuno-istochimica) e come rapporto microalbuminuria/creatininuria.
Obiettivo primario: documentare se l’escrezione di MA implichi un rischio aumentato di complicanze a breve periodo. Obiettivo secondario: relazione tra MA e una serie di parametri fisiopatologici peri-operatori quali ritenzione idrica post-operatoria, BNP, rapporto pa02/Fi02.
Risultati
Sono stati arruolati 59 donne e 112 uomini, età media 63 anni; 19 diabetici, 63 ipertesi e 75 affetti da BPCO. Abbiamo eseguito 80 lobectomie, 8 pneumonectomie, 6 timectomie, e 87 resezioni polmonari sublobari; 122 in toracotomia e 49 VATS. Mortalità postoperatoria: 2 (ARDS); Complicanze maggiori: 9 (chilotorace: 3, insufficienza respiratoria: 3, fistola bronchiale minima: 1, IMA: 1, IRA: 1). Complicanze minori: 16 (FA: 14, perdite aeree > 7 giorni: 2). La MA preoperatoria era normale, valore medio: 0.61 mg/dl (0.48 - 0.79). In prima giornata abbiamo documentato un marcato aumento, valore medio: 4.45 (3.50 - 5.65), p<0.001. Un aumento ancora più spiccato si è osservato nei pazienti diabetici ed ipertesi valore medio rispettivamente: 8.95 (1.54 - 52.09), p<0.001 e 5.852 (4.04 - 8.46), p<0.001. In prima giornata postoperatoria abbiamo trovato differenze statisticamente non significative in relazione all’approccio chirurgico. Le complicanze postoperatorie non sono risultate statisticamente correlate con l’escrezione di MA.
Conclusioni
Il nostro studio conferma che MA è espressione della reazione dell’organismo allo stress chirurgico e costituisce un indice precoce di aumentata permeabilità vascolare in parte rapportato all’entità dello stress. Come atteso, nel post-operatorio, è stato riscontrato incremento maggiore di MA nei pazienti diabetici, ipertesi e sottoposti ad intervento toracotomico, quest’ultimo dato, peraltro, statisticamente non significativo. Non viene confermato il valore prognostico negativo a breve periodo espresso da altri autori
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
