820 research outputs found

    Lliurament premis als guanyadors del Concurs Pearson

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    Lliurament de premis als guanyadors del Concurs Pearson, activitat conjunta de l’assignatura Història de la Matemàtica, la Biblioteca FME i la col·laboració de la Cap d'Estudis d'Estadística

    Lliurament premis als guanyadors del Concurs Pearson

    No full text
    Lliurament de premis als guanyadors del Concurs Pearson, activitat conjunta de l’assignatura Història de la Matemàtica, la Biblioteca FME i la col·laboració de la Cap d'Estudis d'Estadística

    Taxonomy, biostratigraphy, and phylogeny of Oligocene Globigerinitidae (Dipsidripella, Globigerinita, and Tenuitella)

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    The taxonomy, biostratigraphy, and phylogeny of the Oligocene Globigerinitidae (comprising the genera Dipsidripella, Globigerinita and Tenuitella) is reviewed. This family is here included in the Superfamily Globigerinitoidea based on the distinctive wall texture. The group is united by possessing a ‘radially crystalline’ wall texture (the glutinata-type wall) which typically bears pyramidal pustules and in most species is microperforate (pores <1 µm in diameter). The genus Dipsidripella is included in the family here for the first time. In Dipsidripella the wall is often medioperforate (pores 1-2 µm in diameter; danvillensis-subtype). The following species are recognized as valid and occurring in the Oligocene: Dipsidripella danvillensis (Howe and Wallace), Dipsidripella liqianyui Huber and Pearson, Globigerinita glutinata (Egger), Globigerinita uvula (Ehrenberg), Tenuitella angustiumbilicata (Bolli), Tenuitella gemma (Jenkins), Tenuitella munda (Jenkins), and Tenuitella praegemma (Li)

    Parent values and preferences underpinning treatment decision-making in poor-prognosis childhood cancer: a scoping review

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    BACKGROUND: Parents of children who are diagnosed with a poor-prognosis cancer want to be involved in making treatment-related decisions for their child. They often make repeated decisions depending on their child’s response to treatment and can experience decisional regret as a consequence. Understanding parent values and preferences when making treatment-related decisions may help enhance discussions with healthcare professionals and identify additional ways of providing support to this parent population. OBJECTIVES: To explore parent values and preferences underpinning treatment decision-making for children receiving cancer-directed therapy for a poor prognosis cancer. METHODS: A scoping review of research literature and systematic reviews from qualitative, quantitative, and mixed methods studies was conducted following Joanna Briggs Institute methodology. Articles which included parents of a child who received cancer-directed therapy for a poor-prognosis childhood cancer, under the age of eighteen years were considered. Four electronic databases were searched (CINAHL, Medline, PsychINFO, Web of Science Core Collections). Reference and citation lists of all included full-text articles were also searched. Summative content analysis was used to synthesise findings and develop themes. RESULTS: Twelve articles were included. Parent decision-making was affected by underpinning factors: hope for a cure, fear of their child dying and uncertainty. Influencing factors: opinions of others, child’s wishes, and faith and religion had the potential to inform decision-making processes. Parents valued having enough time, being a good parent and being involved in decision-making. Preferences within these values varied resulting in the potential for conflict and ‘trade-offs’ in making decisions. CONCLUSIONS: Parent decision-making in poor-prognosis childhood cancer is complex and extends beyond values and preferences. Underpinning factors and values are consistent through the decision-making process with influencing factors and preferences varying between parents. Preferences can conflict when parents want to continue cancer-directed therapy whilst maintaining their child’s quality of life or can change depending on a parents’ cognitive state as they realise cure might be unlikely

    What does the word ‘Europe’ make you think of? Conceptualisations of Europe in a local context

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    The present article investigates the construction of the sense of belonging toward Europe in the public sphere, employing a case-study conducted in Italy. The author argues that different conceptualisations of Europe are related to diverse “uses” of the media, familiarity with international cultural resources and participation in the transnational public sphere and civil society. These variables affect the construction of Europeans' sense of belonging

    Correction: Yagüe, P., et al. Goals and Challenges in Bacterial Phosphoproteomics. Int. J. Mol. Sci. 2019, 20, 5678

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    The authors wish to make the following corrections to this paper [1]:The author name &ldquo;Gemma Fern&aacute;nez-Garc&iacute;a&rdquo; should be &ldquo;Gemma Fern&aacute;ndez-Garc&iacute;a&rdquo; [...

    Stress in equids undergoing veterinary care and the development of interventions that positively influence the horses' experience

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    Veterinary care can be essential for maintaining the physical health of horses and yet the impact of veterinary care on a horse’s emotional state and how that influences their behavioural responses has not been investigated previously. The term horses is used to describe both horses and ponies. Adverse behavioural responses are unwanted, not only for equine welfare but because veterinarians are frequently injured by the horses they are working with, each sustaining on average around 7-8 significant injuries over the courses of their careers. This study evaluated which aspects of veterinary care horses find stressful, their common behavioural responses in this context and potential ways of improving how they perceive veterinary care. In the context of a veterinary examination, horses are limited in which behavioural responses they can express as they will be restrained to a greater or lesser degree. To determine the range of behavioural responses that may occur and their usefulness in assessing emotional state in the veterinary clinic, a two round Delphi process was undertaken. In the first-round participants from the field of Equitation Science (n=16), Equine Veterinarians (n=10) and Animal Behaviour and Welfare Scientists (n=7) evaluated 11 videos of horse’s behavioural responses to veterinary care. They assigned a score to the degree of stress they perceived each horse to be experiencing and described any behavioural indicators of stress as free text. There was poor agreement on the perceived degree of stress the horses were experiencing and different behavioural indicators were reported by different individuals. The behavioural indicators (41) identified in round one were then re-presented to the participants in a second round where 34/41 indicators were considered useful measures of the horse’s stress response in this context. A feasibility study was then undertaken to determine the best measures of arousal and valence in the context of a veterinary clinic. Horses presenting for veterinary care at an equine hospital (n=30) were filmed during various veterinary interactions (Events) with the horses and the footage was evaluated using a detailed inventory of behavioural responses. Principle component analyses were performed, results of which suggested that the most common behavioural responses to veterinary care were characterised by freeze or flight. Evaluation of the feasibility of different measures of arousal (salivary cortisol, surface eye temperature and heart rate variability) were undertaken on the same cohort of horses. Salivary cortisol concentrations highlighted that horses were in a state of elevated arousal, likely as a consequence of transportation, even before veterinary care commenced. Elevated cortisol concentrations were maintained, most likely due to exposure to veterinary Events, but the lag between an individual Event and concentration peaks / return to baseline meant this was not feasible measure in this context. Surface eye temperature provided data that varied in real time and showed variation between horses and between individual Events. The main limitation of using this measure was the practical challenges trying to capture usable, in focus, and therefore accurate, thermal images of the eye as many horses did not remain still during Events. Heart rate variability parameters (HRV) provided data that varied in real time and showed variation between horses and between individual Events. Moreover, it could be collected remotely and regardless of any behavioural response. In the feasibility study HRV data were collected using a Polar heart rate monitor. However, validation against an ECG showed the Polar to be inaccurate, even following artefact correction. Even when an ECG was used subsequently, manual R peak detection and documentation of arrhythmias was essential to ensure accurate data for HRV analyses were generated. The methodology developed in the feasibility study was used to evaluate the responses of 60 horses undergoing veterinary care in the same equine hospital. The proportion of time a horse was ‘stressed’ was calculated based on the sum total of time in any negative affective state over total time. This study found marked variation regarding which veterinary Events horses appeared to find stressful, both within and between individuals. For example, 13/15 veterinary Events resulted in a range of time an individual horse was scored as ‘stressed’. Negative behavioural responses were characterised by freeze or flight but also fidgeting behaviours, which are well described in other species but poorly documented in horses. Aggressive ‘fight’ responses occurred very infrequently. Further research is required to determine whether training of equine veterinarians to recognise subtle behavioural indicators, across the range of responses (freeze, flight, fidget or fight), can be used to improve equine welfare and reduce the likelihood of occupational injuries. With regard to evaluation of individual Events: • One of the most arousing stimuli, based on behavioural response and elevated heart rate, in the veterinary environment was the sound or sight of another horse walking past and so minimising this stimulus where possible is recommended. • Horses are frequently walked onto a weigh bridge upon entering the equine hospital and this commonly evoked a behavioural response characterised by freeze or flight and elevated heart rate. It is less than ideal that their first experience in a novel environment and first interaction with staff may be a negative one. Weighing a horse after other veterinary Events have been completed or development of a low stress technique would likely be of benefit. • The use of feed during diagnostic local anaesthesia appeared to minimise the proportion of time an equid was scored as ‘Stressed’ compared to when it was not used and so is recommended. • Horses were scored as more ‘Stressed’ when an I.V. injection was administered by a student or nurse in comparison to a veterinarian. Investigation of training to try to mitigate this response should be undertaken. The final study in this thesis evaluated the way in which learning theory could be applied in veterinary practice. Classical counter conditioning was used prior to diagnostic local analgesia (nerve blocks) and the impact on the horse’s stress response was investigated. Twenty-seven cases presenting for lameness evaluation were recruited and randomly assigned to a control or treatment group. In the treatment group the provision of feed (unconditioned stimulus) was paired with someone approaching (conditioned stimulus) the limb. In the control group 14 horses received 24 nerve blocks, in the treatment group 13 horses received 35 nerve blocks. Restraint during the nerve block was at the discretion of the veterinarian performing the procedure. Video footage of horses during the nerve block was evaluated using a fixed list method Qualitative Behaviour Assessment by 5 observers blinded to treatment group. They scored the treatment group as being in a more positive affective state (at ease, relaxed and confident) than the control group (nervous, tense and fearful). However, the difference between groups was only statistically significant once other significant contributing factors such as the type of block were included in the multivariable model. This highlights that many different factors are contributing to how a horse perceives veterinary Events such as nerve blocks but that classical counter conditioning can be used to help horses perceive them more positively. In summary, a horse’s perception of veterinary care will vary markedly between individual animals but also within an individual. Constant evaluation of the horse’s emotional state, based on an understanding of subtle indicators of negative affect, will allow the veterinary team to modify their approach and optimise care of the individual. In addition, it is possible to promote a positive affective state even during aversive procedures such as nerve blocks. This can be achieved in a real-life scenario using classical counter conditioning

    Petrarca e Osberno di Gloucester

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    Si presenta l'edizione commentata delle note autografe di Petrarca contenute nel Par. Lat. 7492, testimonianza della lettura e dell’utilizzo delle Derivationes di Osberno di Gloucester, altrimenti mai esplicitamente menzionate altrove da Petrarca (il titolo e l’autore rimasero a lungo ignoti). In esse Petrarca indica accordi e discordanze con le Derivationes di Uguccione da Pisa.It presents the annotated edition of Petrarch's autograph notes contained in Para Lat. 7492, evidence of reading and the use of Derivationes Osberno of Gloucester, otherwise never explicitly mentioned elsewhere by Petrarch (the title and the author remained unknown for a long time). In them Petrarca indicates agreements and disagreements with the Derivationes of Huguccio

    Le opere storiche di Antonio Ivani da Sarzana

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    Si forniscono alcune osservazioni e contributi al volume Antonio Ivani da Sarzana, 'Opere storiche' in cui sono pubblicate le principali opere storiche di questo illustre umanista, scrittore prolifico impegnato attivamente nella vita civile e politica del tempo. Interessanti spunti di riflessione offre la tradizione manoscritta, in particolare per la presenza di numerosi autografi rivisti dall’autore.We provide some comments and contributions to the volume Antonio Ivani from Sarzana, 'Historical works' which are published in major historical works of this illustrious humanist, prolific writer actively involved in civic and political life of the time. Offers interesting insights into the manuscript tradition, in particular the presence of numerous autographs revised by the author
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