1,723,946 research outputs found
Model Accuracy Data for Post-Construction Evaluation of Forecast Accuracy in Minnesota
No full textThis data was used for the project: Post-Construction Evaluation of Forecast Accuracy
Parthasarathi, Pavithra; Levinson, David (Minnesota Department of Transportation, 2009)This research evaluates the accuracy of demand forecasts using a sample of recently-completed projects in
Minnesota and identifies the factors influencing the inaccuracy in forecasts. The forecast traffic data for this study
is drawn from Environmental Impact Statements (EIS), Transportation Analysis Reports (TAR) and other forecast
reports produced by the Minnesota Department of Transportation (Mn/DOT) with a horizon forecast year of 2010
or earlier. The actual traffic data is compiled from the database of traffic counts maintained by the Office of
Transportation Data and Analysis at Mn/DOT. Based on recent research on forecast accuracy, the inaccuracy of
traffic forecasts is estimated as a ratio of the forecast traffic to the actual traffic. The estimation of forecast
inaccuracy also involves a comparison of the socioeconomic and demographic assumptions, the assumed networks
to the actual in-place networks and other travel behavior assumptions that went into generating the traffic forecasts
against actual conditions. The analysis indicates a general trend of underestimation in roadway traffic forecasts
with factors such as highway type, functional classification, and direction playing an influencing role. Roadways
with higher volumes and higher functional classifications such as freeways are subject to underestimation
compared to lower volume roadways/functional classifications. The comparison of demographic forecasts shows a
trend of overestimation while the comparison of travel behavior characteristics indicates a lack of incorporation of
fundamental shifts and societal changes.Minnesota Department of TransportationParthasarthi, Pavithra K; Levinson, David M. (2017). Model Accuracy Data for Post-Construction Evaluation of Forecast Accuracy in Minnesota. Retrieved from the University Digital Conservancy, https://doi.org/10.13020/D6RW2Z
Ujian Bukan Alasan, Pavithra Buktikan Tiada Yang Mustahil Dengan Semangat Dan Usaha
Get PDFGAMBANG, 9 November 2025 – “Setiap ujian yang datang bukan untuk melemahkan, tetapi untuk menguatkan diri dan hati”.
Itulah pegangan hidup Pavithra Maniam,24, graduan Sarjana Muda Sains Gunaan Bioteknologi Industri dengan Kepujian dari Fakulti Sains dan Teknologi Industri (FIST) yang menempuh jalan penuh liku sebelum akhirnya berjaya menggenggam ijazah pada Majlis Konvokesyen UMPSA ke-20.
Berasal daripada keluarga yang sederhana, bapanya, Maniam Kerisnan, 46, merupakan seorang pemandu lori dan ibunya, Geetha Visvanathan, 44, seorang suri rumah.
Pavithra merupakan anak pertama dalam keluarga yang berjaya menjejakkan kaki ke menara gading
Love Letters to My Child in These Hate-Filled Times
No full textIn a series of three letters, Pavithra describes to their unborn child what it’s like to be pregnant. The first conveys the terror of carrying a new being into a violently homophobic and racist world. The second and third letters recall the desire and beauty that the unborn child sparks in them. In the fourth letter, Pavithra writes to Noor Momo, now six years old, reflecting on the realities of parenting amidst ongoing violence and the uncertainties of the COVID-19 pandemic. In this final letter, Pavithra invokes Noor’s aunts: her sister Raksha, and her dear friends Kriti, Batool, Mabel, and Marie. The words Chitthi, Masi, Khala and Chyama refer to “mother’s sister” in Tamil, Hindi, Urdu, and Nepali, respectively
Interview Transcripts
Get PDFAnonymised interview transcripts collected and analysed in thesis titled 'Constructing Models of Alcohol and Sexual health literacy in adolescence'</span
Constructing models of alcohol and sexual health literacy in adolescence.
No full textIn the UK, research has highlighted the need for improved education in alcohol and sexual health in the adolescent population. Consequently, Relationships and Sex Education and Health Education were made compulsory in 2019. However, preceding research highlighted that school-based alcohol and sexual health education was ill-suited to building associated health skills and competencies. Health literacy as a concept aims to address these issues by providing a framework within which health related competencies and outcomes can be developed. Consequently, the aim of this research was to develop models of alcohol and sexual health literacy in adolescents and further interrogate the use of such models in education, exploring the barriers to developing alcohol and sexual health literacy in adolescents though formal education. A pragmatic, mixed methods approach was utilised to explore the research questions. The study contributed to the field of research by creating robust, theory-based models of alcohol and sexual health literacy and discovering the following: • Current measures of adolescent health literacy are poorly designed, often only accounting for functional health literacy. • There are many barriers that need to be overcome to effectively deliver alcohol and sexual health education in schools, specifically, that competencies in alcohol and sexual health are perceived as challenging to teach and measure within a school setting. • Internationally, curriculum guidelines tend to focus on the risks associated with alcohol and sexual health and fall short in building competencies over knowledge and in aiding educators with instruction. • Introduction of compulsory Relationships and Sexual Health Education and Health Education in the UK will have little significant impact if it is not supported with more training and support for educators.These findings and the models produced have significant connotations for the design and delivery of alcohol and sexual health education in schools
data_bjp_paper_cps_replication – Supplemental material for When Do the Poor Vote for the Right Wing and Why: Status Hierarchy and Vote Choice in the Indian States
No full textSupplemental material, data_bjp_paper_cps_replication for When Do the Poor Vote for the Right Wing and Why: Status Hierarchy and Vote Choice in the Indian States by Pavithra Suryanarayan in Comparative Political Studies</p
Online_Appendix – Supplemental material for When Do the Poor Vote for the Right Wing and Why: Status Hierarchy and Vote Choice in the Indian States
No full textSupplemental material, Online_Appendix for When Do the Poor Vote for the Right Wing and Why: Status Hierarchy and Vote Choice in the Indian States by Pavithra Suryanarayan in Comparative Political Studies</p
Network structure and metropolitan mobility
Get PDFJTLU vol. 7, no. 2, pp. 153-170 (2014)This research aims to develop quantitative measures that capture various aspects of the underlying network structure, using aggregate level travel data from fifty metropolitan areas across the US. The influence of these measures on system performance is then tested using statistical regression models. The results corroborate that the quantitative measures of network structure affect the system performance. The results from this analysis can be used to develop network design guidelines that can be used to address current transportation problems.Parthasarathi, Pavithra. (2014). Network structure and metropolitan mobility. Retrieved from the University Digital Conservancy, 10.5198/jtlu.v7i2.494
Studies on the Effect of Nuclear-penetrating Anti-dsDNA Autoantibody IgG and Recombinant VH Domain in Lupus Nephritis-associated Kidney Cells
No full textThe aim of this study is to investigate the pathological impacts of the anti-dsDNA antibodies, that are basically causative factors in autoimmune diseases. The anti-dsDNA autoantibody 2C10 IgG and its recombinant fragment 2C10 VH domain were tested in the normal murine kidney mesangial cells (MES) and human cervical cancer cell (HeLa) to know the pathogenic aspect of these antibodies. It was observed that the 2C10 IgG and 2C10 VH domain penetrated into the target cells and reduced their cell proliferation and the penetrated autoantibodies simultaneously activated the signal molecules ERK1/2 and p38. Further observation revealed that 2C10 IgG and 2C10 VH persistently activated RSK-1 and upregulated BCL-2 expression. In mesangial cell line, the 2C10 IgG and 2C10 VH stimulated the transcription of pro-inflammatory genes TNF-α, IL-6 and IL-1β through ATF-2 activation enormously, but the same pattern was not observed in HeLa cells. The activation of these signal molecules was linked to the production of pro-inflammatory cytokines, because inhibition of the molecules suppressed the cytokine production. Collectively, the cell-and nuclear-penetrating autoantibodies 2C10 IgG and 2C10 VH seem to play a pathogenic role in mesangial cells through activation of p38, MAPKAPKK2, RSK-1, BCL-2 and ATF-2 and consequent production of pro-inflammatory cytokines.I. INTRODUCTION 1
II. MATERIALS AND METHODS 4
1. Cell Lines 4
2. Antids DNA Monoclonal Antibodies 4
3. Cell signaling Antibodies and Inhibitors 5
4. Cytokine Primers 5
5. Cell proliferation assay 6
6. Confocal Microscopy 6
7. Flow Cytometry for cell cycle analysis 7
8. Western Blotting 7
9. Quantitative realtime PCR 8
10. Statistic analysis 8
III RESULTS 9
1. AntidsDNA autoantibody (autoAb) 2C10 IgG and 2C10 VH have cell penetrating property 9
2. Penetrating autoAbs 2C10 IgG and 2C10 VH inhibit the cell survival in various cell lines 9
3. 2C10 IgG and 2C10 VH fragment activated the ERK1/2 and p38 molecules 15
4. 2C10 IgG and 2C10 VH increased the mRNA level of TNFα, IL6, IL1β in MES cells 20
IV. DISCUSSION 24
V. REFERENCES 28Maste
- …
