369 research outputs found

    Return to work with chronic pain: employers' and employees' views

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    This conference papers given to the Society of Occupational Medicine's Annual Scientific Meeting discusses tensions and some possible ameliorating activities from our 2013 paper of the same name., published in their journal: Wainwright, E., Wainwright, D., Keogh, E. and Eccleston, C. Return to work with chronic pain: employers’ and employees’ views. Occupational Medicine 2013: doi:0.1093/occmed/kqt109. The conference homepage is here;http://www.som-asm.org.uk/Programme_SOM_ASM.aspAbstractBackgroundThe sickness certification and return to work (RTW) of people with chronic pain are important health and economic issues for employees, employers, taxpayers and the UK government. The ‘fit note’ and a national educational programme promoting RTW were introduced in 2010 to curb rising rates of sickness absence. AimsTo investigate employers’ and employees’ experiences of managing RTW when someone has taken sick leave for chronic pain, and to explore the perceived efficacy of the fit note.MethodsA qualitative study, comprising semi-structured interviews with employers who had managed sick leave cases and employees who had experienced sick leave for chronic pain. Interviews were recorded, transcribed and the data analysed using constructivist grounded theory principles.ResultsFive themes were elicited. Firstly, frequent enquiry after health status was seen as intrusive by some employees but part of good practice by employers and acknowledging this difference was useful. Secondly, being able to trust employees due to their performance track record was helpful for employers when dealing with complex chronic pain conditions. Thirdly, feeling valued increased employees’ motivation to return to work. Fourthly, guidelines about maintaining contact with absent employees were useful if used flexibly. Finally, both parties valued the fit note for its positive language, interrogative format and biomedical authority. ConclusionsThe fit note was perceived to be helpful if used in combination with other strategies for managing sick leave and RTW for people with chronic pain. These strategies may be applicable to other fluctuating, long-term conditions with medically unexplained elements. <br/

    Cholesterol metabolism and vascular disease

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    Cholesterol is packaged into lipoprotein particles in the liver and intestine and transported to peripheral tissues for normal cellular function. Reverse cholesterol transport is the mechanism by which excess cholesterol is transported back to the liver and is facilitated by high-density lipoproteins (HDLs). Increased plasma concentrations of cholesterol within the low-density lipoprotein (LDL) molecule contribute to atherosclerotic vascular disease that commonly affects the coronary, cerebral and peripheral vascular circulation.There is now strong evidence to support the use of the statin class of drugs to decrease the risk of cardiovascular disease. Statins inhibit hepatic cholesterol synthesis, increase hepatic low-density lipoprotein cholesterol (LDLc) receptor expression and consequently decrease plasma LDLc, to reduce the risk of myocardial infarction in people at widely varying risk of heart disease. At present, there is limited evidence to support the use of alternative classes of lipid-lowering medications to reduce the risk of cardiovascular disease. Clinical trials are currently ongoing to assess the safety and efficacy of new types of medications to treat dyslipidaemias, the most promising of which are targeted against proprotein convertase subtilysin kexin 9 (PCSK9)

    The Memorial of Prof. William J. Wainwright

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    Editor’s NoteThe Memorial of Prof. William J. WainwrightThe member of Editorial Board of Journal of Philosophical Theological ResearchWilliam “Bill” Judson Wainwright (1935-2020), a distinguished professor emeritus of philosophy at the University of Wisconsin-Milwaukee, was the member of the Editorial Board of the Journal of Philosophical Theological Research (JPTR).Wainwright is the author of several books in various fields of philosophy, especially the philosophy of religion, and numerous articles and chapters. Monotheism and Hope In God (2020), Reason, Revelation, and Devotion: Inference and Argument in Religion (2015), Religion and Morality (2005), and Heart and Reason (1995) are among his published books.His last published article is “God, Love and Inter-religious Dialogue”1, which was published by the Journal of Philosophical Theological Research in the autumn of 2020. Wainwright gave final approval to his paper but unfortunately could not see its publication. He passed away on November 5, 2020, a few days before we published his article. May he be in peace and God’s grace. I never met him but I understood from my contacts with him that “He was a very kind, respected, noble, and patient philosopher.”We decided to dedicate a special issue titled “Theology, Philosophy, and Ethics”: In Memory of William J. Wainwright to him. I would like to express my gratitude to all the philosophers who accepted my invitation and generously and kindly helped us in publishing this special issue by writing their valuable articles. We hope that Wainwright would be pleased with the publication of this issue.I will end my words with this wish, which was Wainwright’s wish too, that: I wish that the followers of monotheistic religions can establish peace and tranquility in the world through inter-religious dialogue, mutual understanding, and extending their love for God to each other.1. Wainwright, W.J. (2020), God, Love, and Interreligious Dialogue, Journal of Philosophical Theological Research, 22(85), 5-13

    Finding a Way Forward. Lessons from the Corbyn Project in the UK (James Schneider interviewed by Hilary Wainwright)

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    Within hours of Jeremy Corbyn becoming leader of the British Labour Party, the gloves were off. The Parliamentary Labour Party (PLP), the mainstream media (assisted by much of the Labour Party’s administrative apparatus) and the British capitalist class were all intensely hostile and launched a relentless attack that constantly stymied Corbyn’s project of a transformative socialist government, culminating in the party’s heavy defeat in the general election of December in 2019, in which the right-wing populist project of ‘Brexit’ (leaving the European Union) split Labour’s members and its electoral base. Corbyn and his supporters were quickly marginalized, as the right wing reasserted its grip under the new leader, Keir Starmer. James Schneider not only had a ringside seat at all these events, but was sufficiently part of the team to feel keenly the moments of exhilaration, sweat and pain of the five-year struggle, while all the time knowing, from his year as Momentum’s National Organizer, the vast untapped potential for movement initiative and mobilizations that lay beyond the ‘tyranny of the immediate’ which dominated life in the Leader’s office in Westminster. In this interview, he assesses the strengths and weaknesses of the extra-parliamentary forces that backed Corbyn, from the low ebb of trade union organization when Corbyn first became leader to the limited but important ways in which the new leadership of the Labour Party revalidated trade unions, and the positive legacy of the Corbyn leadership in encouraging popular self-confidence and politicization. At a time when many on the left are leaving or considering leaving the Labour Party, Schneider urges a strategy which transcends the ‘inside the party or out of it’ dichotomy which has constantly exhausted left thinking in the UK. Instead, he outlines the idea of a hybrid movement rooted primarily in communities and workplaces while at the same time, without compromising its mobilizing and campaigning energies, continuing the struggle for democratic control of the Labour Party. Schneider is interviewed in May 2021 by Hilary Wainwright, editor of Red Pepper and contributing editor to the Socialist Register, and author of numerous books on the politics of the left. Wainwright has long been an advocate of the need for the left across Europe to experiment in ‘parties of a new kind’ that would break from both traditional social democracy and the vanguard party models of the far left

    Bidirectional relationships and disconnects between NAFLD and features of the metabolic syndrome

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    Non-alcoholic fatty liver disease (NAFLD) represents a wide spectrum of liver disease from simple steatosis, to steatohepatitis, (both with and without liver fibrosis), cirrhosis and end-stage liver failure. NAFLD also increases the risk of hepatocellular carcinoma (HCC) and both HCC and end stage liver disease may markedly increase risk of liver-related mortality. NAFLD is increasing in prevalence and is presently the second most frequent indication for liver transplantation. As NAFLD is frequently associated with insulin resistance, central obesity, dyslipidaemia, hypertension and hyperglycaemia, NAFLD is often considered the hepatic manifestation of the metabolic syndrome. There is growing evidence that this relationship between NAFLD and metabolic syndrome is bidirectional, in that NAFLD can predispose to metabolic syndrome features, which can in turn exacerbate NAFLD or increase the risk of its development in those without a pre-existing diagnosis. Although the relationship between NAFLD and metabolic syndrome is frequently bidirectional, recently there has been much interest in genotype/phenotype relationships where there is a disconnect between the liver disease and metabolic syndrome features. Such potential examples of genotypes that are associated with a dissociation between liver disease and metabolic syndrome are patatin-like phospholipase domain-containing protein-3 (PNPLA3) (I148M) and transmembrane 6 superfamily member 2 protein (TM6SF2) (E167K) genotypes. This review will explore the bidirectional relationship between metabolic syndrome and NAFLD, and will also discuss recent insights from studies of PNPLA3 and TM6SF2 genotypes that may give insight into how and why metabolic syndrome features and liver disease are linked in NAFLD

    Constructing gendered workplace 'types': The weaver-millworker distinction in Dundee's jute industry c.1880-1910

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    Victorian and Edwardian Dundee was labelled a ‘woman’s town’ due to the high proportion of women who worked in the city’s staple jute industry. In this article, drawing on a range of contemporary sources, I use the work of feminist historians and Foucauldian notions of discourse to interrogate this label and explore why and how working women came to be marked as a particular problematic group. Further, in questioning this group, I demonstrate how two specific workplace ‘types’ – the weaver and millworker – were identified and constructed in contrast to one another. This article probes the processes through which these two ‘types’ were created, contested and performed in relation to the segregations and working conditions of their respective workplaces, and argues for a markedly spatial interrogation of gender identities and the category ‘working woman’

    The Wilson Building and the Wainwright Building, analysis and formal coincidences in the design

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    El presente artículo analiza y contrasta a partir de la observación al edificio Wilson (1946), del arquitecto peruano Enrique Seoane Ros, con el conocido edificio de la escuela de Chicago, del arquitecto norteamericano Luis Sullivan, de nombre Wainwright Building (1891). Las coincidencias en el diseño entre ambas edificaciones son numerosas, a pesar de que el estilo difiere y la distancia en el tiempo de ambas son de cincuenta y cinco años, lo que nos hace suponer que el edificio de Sullivan fue una influencia e inspiración para la obra del arquitecto Enrique Seoane Ros. Aclaro que esta visión es personal y única del autor de este artículo, la cual comparto para su lectura y visualización.This article analyzes and compares from the observation of the Wilson building (1946) by the Peruvian architect Enrique Seoane Ros with the famous building of the Chicago school, by the North American architect Luis Sullivan named Wainwright Building (1891), the coincidences in the design between both buildings, are great despite the fact that the style differs and the distance in time of both are 55 years, which makes us assume that the Sullivan building was an influence and inspiration for the work of the architect Enrique Seoane Ros. I clarify that this vision is personal and unique to the author of this article, which I share for your reading and viewing
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