508 research outputs found
Quinn, Rollin David (1869–1928)
No full textRollin D. Quinn was a minister, conference and union conference president, General Conference field secretary, and author
Sulfur-containing metabolites in radishes. Further exploration of glucoraphenin desulfation
No full textGlucoraphenin (GRE), found in radishes, holds the unique structural specificity of a Michael acceptor vinyl sulfoxide site. For this reason, desulfo-GRE resulting from enzymatic desulfation is converted into thioimidate N-oxides. Under longer reaction times, a new sulfur-containing compound was isolated and characterized as a cyclic thiohydroximate. © 2013 Copyright Taylor and Francis Group, LLC.© 2013 Copyright Taylor and Francis Group, LLC
Detection of Short CO2 Pulses
No full textTitle: Detection of Short CO2 Pulses, Author: Daniel F. Rollin, Location: ThodeA passively mode-locked multi-atmosphere CO2 laser was used to produce sub-nanosecond pulses. After up-conversion of the 10.6 um radiation in a proustite crystal detction was done with a streak camera-optical multichannel analyser combination. Pulses shorter than 100 psec (FWHM) were recorded.ThesisMaster of Engineering (ME
Paysages de Saint-Denis / Anne Lombard-Jourdan ; avec la collab. de Christine Lakah ; préf. de Patrick Braouezec et Jean Rollin
No full textContient une table des matièresAvec mode text
Burhans, Rollin S., 1914-2005 - Relating to (SC 3112)
No full textFinding aid only for Manuscripts Small Collection 3112. Typescripted account by an unknown author of an intercession by Rollin S. Burhans, pastor of Crescent Hill Baptist Church, Louisville, Kentucky, which prevented the planned suicide of “Mr. Martin,” a musician traveling with the Ice Capades
Glucosinolate Profile of Croatian Stenoendemic Plant Fibigia triquetra (DC.) Boiss. ex Prantl.
No full textAs part of our ongoing investigation of the stenoendemic plants belonging to the Brassicaceae family, we report on the chemistry of Fibigia triquetra (DC.) Boiss. ex Prantl for the first time. Different plant parts (flower, leaf, stem, and seed) of F. triquetra were characterized and quantified for glucosinolates (GLs) according to the ISO 9167-1 EU official method based on the HPLC analysis of desulfo-GLs. A taxonomic screening showed that F. triquetra contained relatively high levels of C-4 GLs, namely but-3-enyl GL (gluconapin, 1a), 4-methylsulfanylbutyl GL (glucoerucin, 3a), and 4-methylsulfinylbutyl GL (glucoraphanin, 5a). GC-MS analysis of the volatile fractions obtained after enzyme hydrolysis and/or HPLC-ESI-MS of intact GLs confirmed the GL profile. Four minor GLs, namely isopropyl GL (glucoputranjivin, 6a), sec-butyl GL (glucocochlearin, 7a), pent-4-enyl GL (glucobrassicanapin, 2a), and 5-methylsulfanylpentyl GL (glucoberteroin, 4a) were also identified and quantified while 4-methylpentyl GL, 5-methylhexyl GL, and n-heptyl GL, were tentatively identified by GC-MS of their degradation products. Based on the major, as well as the minor GLs, this study shows differences in chemotaxonomy between F. triquetra and the related Degenia velebitica (Degen) Hayek as well as other investigated species of the genus Fibigia
Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds
No full textDietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of enantiopure R-sulforaphane based on the enzymatic hydrolysis of its natural precursor glucoraphanin. As an alternative to broccoli seeds, we have exploited Tuscan black kale seeds as a suitable source for gram-scale production of glucoraphanin. The defatted seed meal contained 5.1% (w/w) of glucoraphanin that was first isolated through an anion exchange chromatographic process, and then purified by gel filtration. The availability of glucoraphanin (purity ≈ 95%, weight basis) has allowed us to develop a novel simple hydrolytic process involving myrosinase (EC 3.2.1.147) in a biphasic system to directly produce R-sulforaphane. In a typical experiment, 1.09 g of enantiopure R-sulforaphane was obtained from 150 g of defatted Tuscan black kale seed meal
Anticancer activity of glucomoringin isothiocyanate in human malignant astrocytoma cells
No full textIsothiocyanates (ITCs) released from their glucosinolate precursors have been shown to inhibit tumorigenesis and they have received significant attention as potential chemotherapeutic agents against cancer. Astrocytoma grade IV is the most frequent and most malignant primary brain tumor in adults without any curative treatment. New therapeutic drugs are therefore urgently required. In the present study, we investigated the in vitro antitumor activity of the glycosylated isothiocyanate moringin [4-(alpha-L-rhamnopyranosyloxy)benzyl isothiocyanate] produced from quantitative myrosinase-induced hydrolysis of glucomoringin (GMG) under neutral pH value. We have evaluated the potency of moringin on apoptosis induction and cell death in human astrocytoma grade IV CCF-STTG1 cells. Moringin showed to be effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition. In addition, oxidative stress related Nrf2 transcription factor and its upstream regulator CK2 alpha expressions were modulated at higher doses, which indicated the involvement of oxidative stress mediated apoptosis induced by moringin. Moreover, significant reduction in 5S rRNA was noticed with moringin treatment. Our in vitro results demonstrated the antitumor efficacy of moringin derived from myrosinase-hydrolysis of GMG in human malignant astrocytoma cells. (C) 2016 Elsevier B.V. All rights reserved
Review of John Rollin Ridge: His Life & Works
No full textJames Parins has produced the first booklength study of John Rollin Ridge, the mixedblood Cherokee writer and California newspaper editor. Ridge (1827 -67) packed a great deal into his relatively short life and certainly deserves a biography. He grew up during the violent years of Cherokee removal and postremoval factionalism; when only twelve, he saw his father assassinated; he later killed an enemy and fled to California to become a forty-niner; and he became well-known as a poet, editor, and political commentator. Ridge is best remembered as the author of The Life and Adventures of Joaquin Murieta, the Celebrated California Bandit (1854), one of the first novels written by an author of American Indian extraction
Comparison of bioactive phytochemical content and release of isothiocyanates in selected brassica sprouts
No full textThe consumption of brassica sprouts as raw vegetables provides a fair amount of glucosinolates (GLs) and active plant myrosinase, which enables the breakdown of GLs into health-promoting isothiocyanates (ITCs). This study reports the determination of the main constituents related to human health found in edible sprouts of two Brassica oleracea varieties, broccoli and Tuscan black kale, and two Raphanus sativus varieties, Daikon and Sango. Radish sprouts exhibited the highest ability to produce ITCs, with Daikon showing the greatest level of conversion of GLs into bioactive ITCs (96.5%), followed by Sango (90.0%). Tuscan black kale gave a value of 68.5%, whereas broccoli displayed the lowest with 18.7%. ITCs were not the exclusive GL breakdown products in the two B. oleracea varieties, since nitriles were also produced, thus accounting for the lower conversion observed. Measuring the release of plant ITCs is a valuable tool in predicting the potential level of exposure to these bioactive compounds after the consumption of raw brassica sprouts
- …
