1,720,967 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Repairing Casting Defects by High Pressure Cold Spraying Method
The objective of this study was to investigate whether high pressure cold spray can be used to repair casting defects. The experiment conducted involved microstructural observations and mechanical property measurements of 316L stainless steel powder (20-44μ) cold sprayed coatings deposited onto a cast CA6NM martensitic stainless-steel substrate. The substrate was cold sprayed by hand using a VRC GEN III Cold Spray System with Nitrogen as the carrier gas. Substrate holes with different sizes and preparation techniques were created to mimic casting porosity. The backside of the plate was machined smooth and cold spray filled to perform ASTM C633 adhesion testing. Microstructural studies revealed cracks and improper bonding at the coating-substrate interface in many of the filled holes.</p
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Elucidating the Roles of Lunatic Fringe in Pancreatic Ductal Adenocarcinoma
Pancreatic cancer is an aggressive form of cancer that is very difficult to detect, treat resulting in a high rate of mortality. Understanding the molecular basis of pancreatic cancer and identifying new molecular targets for designing therapeutic interventions is paramount for improving outcomes in this disease. Notch signaling is a vital developmental signaling pathway that has been implicated to play both oncogenic and tumor suppressive roles in pancreatic cancer. Previous studies from other groups have shown that O-linked glycosylation of Notch signaling plays a key role in the regulation of Notch signaling. Lunatic fringe (Lfng) is one of the glycosyltransferases that modifies the O-fucosylated Notch receptors. Dysregulation of glycosylation mediated by Lfng has been previously shown to result in several Notch-related developmental disorders. While targeting Notch signaling pathway in cancers has been explored as a potential therapeutic intervention for several cancers, the status of Notch-related glycosylation has not been explored.
In the first set of studies, we have characterized the expression pattern of Notch receptors, ligands and Notch-related glycosyltransferases in human pancreatic cancer cell lines and human pancreatic cancer specimens from our Rapid Autopsy Program. These studies identified potential molecular targets in the Notch signaling pathway. Findings of these studies helped identify Lunatic fringe, a Notch-related glycosyltransferase, to have increased expression in human pancreatic cancer. To elucidate the role of Lfng in human pancreatic cancer, we utilized multiple genome editing approaches to engineer three human pancreatic cancer cell lines with a complete lunatic fringe knockout. These cell lines served as model systems to identify the phenotypic changes in pancreatic cancer cells upon loss of functional Lfng gene. Furthermore, we performed next-generation sequencing and polar metabolite analysis to
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help elucidate the impact of Lfng on the transcriptional and metabolic profile of human pancreatic cancer cell lines.
The findings of our study reveal that Lfng impacts the tumorigenicity of pancreatic cancer possibly through global changes in transcription and metabolic reprogramming of cancer cells. These findings of this study provide the basis for further detailed exploration into the role of Notch-related glycosylation in human pancreatic cancer
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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