1,720,976 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Cyclic alopecia in epidermal Lsd1-deficient mice : Lsd1 directs bulge stem cell maintenance and coordinates the hair cycle
Computational Studies of Ion Channel Blockers and Protein Aggregation
The ion channels are important membrane bound proteins and multi-therapeutic target for a number of diseases. There are many scorpion toxins reported to bind with KV1 channels. We have identified a plant toxin. We have studied binding of two different sequence length peptides, 1-47 and 10-44 with KV1.3 and KV1.1 channels. The binding complex structures are obtained by molecular docking and stability of the complexes are checked by MD simulations. The pore inserting residue is predicted as K33. The KV1.1-toxin complexes are found to be unstable, and toxin doesn't block the pore in MD simulations. The predicted binding free energies for both complexes of KV1.3-toxin are within the range of experimental values with picomolar and nanomolar activities, respectively. Experiments have also confirmed that Toxin(1-47) does not block the current with KV1.1 channel as well. The inward-rectifier potassium (Kir) channels play significant roles in several physiological disorders. I have studied binding of honey bee toxin called tertiapin (TPN) with Kir3.x channels. K21 is predicted to be the pore inserting residue. The binding free energies are calculated and validated with experimental value. I have studied TPN complexes with Kir3.1 and Kir 3.3 and explained insensitivity of TPN to these channels. A few crystal structures of bacterial sodium channels have been determined but the crystal structures of mammalian ones have not been resolved yet. So, it is important to understand similarities and differences between the bacterial and mammalian channels. The validated homology modeled NaV1.4 complexed with GIIIA system provides a good model for such comparisons. Here I have studied the binding of GIIIA to the bacterial sodium channels NaVAb and NaVRh by combination of docking and MD simulations then the potential mean forces are constructed. Comparison of the binding mode of GIIIA between mammalian and bacterial channels. Protein aggregation affects both human physiological functions and bioengineered products so finding methods to prevent aggregation will we very useful. It is an important area of investigation which could be facilitated by a molecular-level understanding of dimer formation, which is the first step in aggregation. Here we propose a computational method based on molecular dynamics simulations that will facilitate finding aggregation-prone regions on human lysozyme HL[D67H], noting that the wild type HL doesn't aggregate
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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