1,721,033 research outputs found

    Correction: Current state-of-the-art of adrenal surgery in Italy: the cancer risk in surgical adrenal lesions (CRISAL) survey

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    In this article some authors name were missing from the CRISAL collaborative group. These authors are list. • Ugo Boggi • Riccardo Casadei • Massimiliano Fabozzi • Mario Guerrieri • Gabriele Materazzi • Gianluigi Moretto • Micaela Piccoli • Paolo Prosperi • Chiara Dobrinja The original article has been corrected

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Laparoscopic right colectomy reduces short-term mortality and morbidity. Results of a systematic review and meta-analysis

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    Purpose: While definitive long-term results are not yet available, the global safety and oncologic adequacy of laparoscopic surgery for right colectomy remain controversial. The aim of the study was to evaluate differences in safety of laparoscopic right colectomy, compared with open surgery, with particular attention to cancer patients. Methods: A systematic review from 1991 to 2014 was performed searching the MEDLINE and EMBASE databases (PROSPERO Registration number: CRD42014015256). We included randomised and controlled clinical studies comparing laparoscopic and open resection for rectal cancer. Primary endpoints were 30 days mortality and overall morbidity. Then, a meta-analysis was conducted by a fixed-effect model, performing a sensitivity analysis by a random-effect model. Relative risk (RR) was used as an indicator of treatment effect; a RR less than 1.0 was in favour of laparoscopy. Publication bias was assessed by funnel plot, heterogeneity by the I2 test and subgroup analysis on oncologic patients. Results: Twenty-seven studies, representing 3049 patients, met the inclusion criteria; only 2 were randomised for a total of 211 patients. Mortality was observed in 1.2 % of patients in the laparoscopic group and in 3.4 % of patients in the open group. The overall RR was 0.45 (95 % CI 0.21–0.93, p = 0.031). The raw incidence of overall complications was significantly lower in the laparoscopic group (16.8 %) compared to the open group (24.2 %). The overall RR was 0.81 (95 % CI 0.70–0.95, p = 0.007). Conclusions: Based on the evidence of few randomised and mostly controlled series, mortality and morbidity were significantly lower after laparoscopy compared to open surgery

    Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery

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    This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of intraoperative neuromonitoring (IONM) versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery

    Hybrid laparo-endoscopic techniques for challenging colorectal lesions: a systematic review

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    Background: Colorectal cancer screening has increased the detection of polyps requiring resection, but standard endoscopic techniques such as endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) are often unsuitable for large, fibrotic, or anatomically challenging lesions. Segmental colectomy remains definitive but carries substantial morbidity, particularly for benign disease. Laparo-endoscopic cooperative surgery (LECS) and related hybrid techniques have emerged as minimally invasive alternatives bridging the gap between endoscopic and surgical resection. Methods: A systematic review was performed according to PRISMA guidelines, querying PubMed, Embase, and Cochrane databases (1985-2024). Studies reporting combined laparoscopic-endoscopic resections for colorectal lesions unsuitable for standard endoscopic treatment were included. Outcomes assessed included additional surgery, adenocarcinoma detection, complication rates, surgery for complications, conversion to open surgery, and recurrence. Random-effects models were used to calculate pooled proportions and 95% confidence intervals (CIs). Results: Twenty-seven studies encompassing 1112 patients were included. The pooled rate of additional surgery was 5% (95% CI 3-8%; I2 = 0%), including 7% (95% CI 5-9%) for oncologic indications. Adenocarcinoma was identified in 12% of resected lesions (95% CI 8-16%), underscoring limitations of preoperative staging. Overall complications occurred in 7% (95% CI 5-10%), with surgery for complications required in only 1% (95% CI 0-2%). Conversion to open surgery occurred in 2% (95% CI 1-3%). Long-term follow-up demonstrated a local recurrence rate of 3% (95% CI 2-6%; I2 = 0%). Conclusions: Hybrid laparoscopic-endoscopic resections are safe, effective, and reproducible options for complex colorectal lesions not amenable to standard endoscopic resection. These techniques achieve low complication and recurrence rates while preserving bowel and minimizing morbidity associated with colectomy. Given the 12% incidence of unexpected adenocarcinoma, intraoperative adaptability and multidisciplinary expertise are essential. Prospective multicenter studies with standardized reporting are needed to refine patient selection and confirm long-term oncologic safety

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Oncologic and survival outcomes of pT2N0 rectal adenocarcinoma treated by transanal local excision: a retrospective cohort study

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    Background: The optimal management of pT2N0 rectal adenocarcinoma remains controversial, especially when tumours are incidentally diagnosed after local excision. Although total mesorectal excision (TME) is the standard approach, its associated morbidity has led to the exploration of conservative strategies. This study compares oncologic outcomes amongst three post-excision management options: salvage surgery, adjuvant radiotherapy, and no further treatment. Methods: This retrospective cohort comprised 90 patients with pT2N0 rectal adenocarcinoma who were treated by transanal excision at a single tertiary centre from 1993 to 2025. All patients were staged N0 on MRI and divided into three groups: Group A (no further treatment), Group B (adjuvant radiotherapy), and Group C (completion salvage surgery). The primary outcomes were overall survival (OS) and disease-free survival (DFS), with additional analyses of histopathologic prognostic factors. Results: Median follow-up was 31 months. OS varied significantly across groups (p = 0.015), with the highest survival in Group B, followed by Group C and Group A. DFS showed no significant difference between groups. Patients in Group B had the lowest mortality (8.7%) and recurrence (30.4%) rates. Tumour budding was a significant predictor of poor prognosis in multivariate analysis. Local excision alone was associated with higher recurrence and mortality rates. Conclusion: In selected patients with pT2N0 rectal cancer discovered after transanal excision, adjuvant radiotherapy may provide outcomes comparable to salvage surgery and serve as an alternative in patients not suitable for surgery. High-risk histopathologic features should inform further management, as local excision alone was associated with worse outcomes. Multidisciplinary evaluation remains crucial for treatment planning

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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