1,721,041 research outputs found
New solution free and polymer anchored chiral bispidine-based amino alcohols. Synthesis and screening for the enantioselectiveaddition of diethylzinc to benzaldehyde
No full textRange Restriction to Harden CNNs Against Hardware Faults: A Broad Empirical Analysis
Full text linkDue to the increasing use of Deep Learning in mission/safety-critical application contexts, in the recent past several techniques have been designed to harden the system to guarantee its correct behavior even in presence of faults affecting the hardware. Often, such new techniques are evaluated on a reduced set of Convolutional Neural Network (CNN) models and/or data sets, such that their generality and robustness could actually be limited. This paper presents a broad and systematic experimental evaluation of a state-of-the-art range restriction technique presented in literature, i) by applying it to a large set of CNNs, implementing different functional tasks, and ii) by using multiple datasets. The obtained results demonstrate that the effectiveness of the technique highly depends on the complexity of the considered task; in particular, classification CNNs benefit the most, while regression, image segmentation, and object detection are subject to different levels of benefits
Comparative phytochemical and morphological analyses of three Italian Primula species
No full textThe taxonomy of alpine Primula species has long been in dispute because of high morphologic variability and several hybridisations. In Primula species, the trichome height and the colour of hair-tips are usually indicated as diacritic characters, but in our experience this is not adequate. The present study, focused on Primula auricula, Primula daonensis and Primula hirsuta, therefore proposes the use of other morphologic trichome parameters (size and dimensional ratio of stalk, neck and gland head). Phytochemical investigations about the flavonoid composition (epicuticular and vacuolar) of leaves, as taxonomic markers, have also been performed. We report the isolation and identification of two new flavonol glycosides, isorhamnetin 3-O-(2,6-di-O-β-D-glucopyranosyl-β-D-glucopyranoside) (1) and kaempferol 3-O-(2-O-α-L-rhamnopyranosyl-6-O-β-D-xylopyranosyl-β-D-glucopyranoside) (2) and of eight known flavonoids. Size and dimensional ratio of the three trichome elements (stalk, neck and glandular head) are typical for each species analysed. The flavonoid profile well characterise the entities under study. Three different profiles have been obtained with both vacuolar and epicuticular flavonoids. The morphologic and phytochemical markers proposed in this work seem to be parameters which significatively discriminate the species under stud
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Natural products as building blocks and leads for the synthesis of new anticancer compounds
No full textThe presentation will be focused on the different ongoing projects in the field of natural products with the aim to forge a possible collaboration in the frame of interdisciplinary projects. At this period three different research approaches are being developed using Natural products as subject: a) synthesis of new self-assembling compounds obtained by modification of cyclopamine, paclitaxel, podophyllotoxin, camptothecin and epothilone A;1-3 b) design and synthesis of new hybrid compounds;4 c) target and diversity-oriented synthesis.5 The final aim is the discovery of new anticancer compounds, the improvement of the biological activity or the faciliting of the delivery.6 References:
[1]. Fumagalli G., Passarella D. et al. (2015), ChemPlusChem DOI: 10.1002/cplu.201500156
[2]. Borrelli, S., Fumagalli G.; Passarella D. et al. (2015) ChemPlusChem, 80: 47-49
[3]. Borrelli, S., Passarella D. et al. (2014) Eur.J.Med.Chem (2014), 85: 179-190
[4]. Marucci C., Passarella D, manuscript to be submitted
[5]. Christodoulou M., Calogero F., Passarella D. et al. (2015), Eur.J.Med.Chem 92: 766-775 and refs therein
[6]. Christodoulou M., Passarella, D. et al. (2014) Drug Discovery Today 19, 1547 – 156
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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