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Trigeminal neuralgia, migraine and sympathetic hyperactivity in a patient with Parry–Romberg syndrome
Parry–Romberg syndrome is a rare disorder of unknown aetiology that involves slowly progressive but self-limited wasting of subcutaneous tissues on one side of the face, usually in the distribution of a branch of the trigeminal nerve. In an internet survey of 205 people on the mailing list of the ‘Romberg's Connection’ site, 52% reported suffering from migraine and 46% from facial pain, almost always affecting the same side as the atrophy. Headaches and facial pain have also featured in case reports, sometimes in association with an intracranial aneurysm or radiological signs of ipsilateral brain pathology.
We had the opportunity to examine trigeminal and cervical sympathetic nerve function in a woman with right-sided Parry–Romberg syndrome, migraine and trigeminal neuralgia. We wished to determine whether signs of trigeminal or cervical sympathetic hyperactivity were associated with the facial hemiatrophy, because aberrant cranial nerve function has been implicated in the pathophysiology of Parry–Romberg syndrome
The mathematical research of William Parry FRS
In this article we survey the mathematical research of the late William (Bill) Parry, FRS
A new fireworm (Amphinomidae) from the Cretaceous of Lebanon identified from three-dimensionally preserved myoanatomy
oai:nhm.openrepository.com:10141/601424© 2015 Parry et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and
reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to
the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver
(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. The attached file is the published version of the article.NHM Repositor
Parry, Eldryd: transcript of an audio interview (12-Jul-2016)
Interview with Professor Sir Eldryd Parry, conducted by Professor Tilli Tansey, for the History of Modern Biomedicine Research Group, 12 July 2016, in the School of History, Queen Mary University of London. Transcribed by Mrs Debra Gee, and edited by Professor Tilli Tansey, Mr Adam Wilkinson and Ms Caroline Overy. The technical support was undertaken by Mr Alan Yabsley. Professor Sir Eldryd Parry KCMG OBE MD FRCP (b. 1930) studied medicine at Cambridge and Cardiff, and was seconded from 1960 to 1963 to University College Hospital, Ibadan, Nigeria. In January 1966 he returned to Africa at Haile Selassie I University, Addis Ababa, and left in 1969 to take the Chair of Medicine at Ahmadu Bello University, Zaria, Nigeria. In 1977 he became the Foundation Dean of Medicine at the University of Ilorin, Nigeria, where he introduced a radical Community Based Education and Service (COBES) programme. From 1980 to 1985 he was Dean and Professor of Medicine at the now Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. He was Senior Editor of 'Principles of Medicine in Africa' until 2009 (4th Edition, 2013). He is an Honorary Fellow at Cardiff University, Emmanuel College Cambridge, the London School of Hygiene & Tropical Medicine, the Royal College of Surgeons of England, the College of Physicians and Surgeons of Ghana, and a Foundation Member of the Faculty of Medicine and Surgery of Amoud University, Somaliland. In 1988 he founded Tropical Health and Education Trust (THET), which he chaired until 2007. He was given a Lifetime Achievement Award by the Royal Society of Tropical Medicine and Hygiene in 2007. He received the OBE in 1982, and was appointed KCMG in 2011.The History of Modern Biomedicine Research Group is funded by the Wellcome Trust, which is a registered charity (no. 210183). The current interview has been funded by the Wellcome Trust Strategic Award entitled “Makers of modern biomedicine: testimonies and legacy” (2012-2017; awarded to Professor Tilli Tansey)
How Socratic Is the “Noble Art of Sophistry”? Tracing the Gennaia Sophistike of the Sixth Diaeresis Back to Old Comedy
Several scholars agree in identifying the “sophistry” outlined in the 6th diaeresis of Plato’s Sophist with the Socratic elenchus (see esp. Cornford 1935, 177-179). In fact, refuting someone “when (s)he thinks (s)he is saying something though (s)he is saying nothing” until (s)he feels ashamed for the opinions (s)he previously held (230c-d), is a kind of purification that strongly resembles Socrates’ elenctic activity. According to Plato and other first-generation Socratics, the shame triggered by Socrates plays a pivotal role in transforming the unfounded pretense of knowledge of Socrates’ interlocutors into an admission of ignorance. As Rosen has pointed out, the 6th diaeresis ends with a definition not of the sophist, but of “a hybrid of the sophist and the philosopher” (1983,(1983,131). This is surprising, as one explicit aim Plato pursues very often (in the Sophist as well as in many other dialogues) is to distinguish between, in most cases even to counterpose, the sophist and the philosopher. This raises the question of what kind of sophistry Plato has in mind at 226B-231B. In this paper I claim that in the 6th diaeresis Plato points at a definition of the sophist that merges both the professional sophists and Socrates—a definition that can be traced back to Old Comedy. Here, the word sophistes encompasses “intellectuals” of various kinds (sophists, philosophers, phusiologoi, and even the initiates to mystery cults such as Orphism or the Eleusinian Mysteries) that were lampooned not only in Aristophanes’s Clouds, but also in other comedies by playwrights who were active in the decade before 423 BC (such as Eupolis, Ameipsias, and Plato Comicus). In this paper, I show how Plato’s account of sophistry at 226B-231B depends on a variety of comic motifs
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Origin of the Parry arc
Laboratory experiments to determine the preferred orientation of free-falling hexagonal prisms were performed at Reynolds numbers appropriate to falling ice crystals in the atmosphere. Hexagonal plates orient with their c axis vertical for aspect ratios < 0.9, whilst hexagonal columns fall with their c axis horizontal. A secondary alignment is also observed: regular hexagonal columns fall preferentially with two prism facets aligned vertically and not horizontally – the latter scenario was previously assumed to be responsible for the rare Parry arc. However, if the column is made scalene in its cross-section, it can orient such that a pair of prism facets is horizontal. This finding indicates that the development of scalene crystals may be key to the production of certain ice-crystal optical phenomen
Peter W. Billings, Parry D. Sorensen, Harold P. Fabian, President Fletcher, August 16, 1969, University of Utah
Photo showing Harold P. Fabian (center) receiving an honorary degree at University of Utah graduation ceremonies, August 16, 1969. Peter W. Billings on left, Parry D. Sorensen and University president James C. Fletcher on righ
Assembly studies of six intestinal intermediate filament (IF) proteins B2, C1, C2, D1, D2, and E1 in the nematode C-elegans.
The dimerisation properties of six intestine-expressed intermediate filament (IF) proteins (B2, C1, C2, D1, D2, E1) were analysed in blot overlay assay on membranes containing all of the eleven recombinant C. elegans IF proteins (A1, A2, A3, A4, B1, B2, C1, C2, D1, D2, and E1). The interactions detected in the blot assays exclusively comprise intestine-expressed IF proteins and the protein A4, which is found in the dauer larva intestine. About 86% of these interactions are heterotypic, while the remaining interactions relate to C1, C2, and D2 homodimers. These multiple modes of interaction were also supported by calculations of the numbers of possible interchain ionic interactions derived from the individual rod sequences. The results predict that the six B2, C1, C2, D1, D2, and E1 IF proteins are able to form as many as eleven different heteropolymeric and three homopolymeric IFs in the C. elegans intestine. This simple model of the intestinal IF meshwork enables us to speculate that our previously reported triple RNAi worms arrested or decreased their growth because of feeding reduction due to morphological defects of the mechanically compromised intestine
Parry Romberg Syndrome: 7 Cases and Literature Review
Parry Romberg syndrome is a rare progressive hemiatrophy of the face that typically occurs in children and young adults and has a peculiar progression that ceases without apparent cause after a highly variable period. Only a subset of patients with Parry Romberg syndrome will develop secondary neurologic or ophthalmologic symptoms, and prognosis is highly variable. Inconsistency in the pattern of atrophy and the development of associated symptoms in patients with Parry Romberg syndrome has made it challenging to diagnose, prognosticate, and treat. The precise etiology of this disease remains unknown, but some authors have implicated sympathetic cervical ganglion dysfunction, abnormal embryogenesis, autoimmune and inflammatory mechanisms, or vasculopathy as potential causes. We present 7 cases of Parry Romberg syndrome and their associated clinical and imaging findings with specific attention to the radiographic characteristics of this disease
Phthiracarus membranifer Parry, 1979, sp. nov.
<p>Phthiracarus membranifer sp. nov.</p> <p>(Fig. 11A-C)</p> <p>Adult: Small and weakly sclerotized. The aspis (Fig. 11C) ranges in length from 213 - 324 µm with a greatest width of 157 - 243 µm. All the dorsal setae are fine and short. Setae (il) are about 1-5 times the length of setae (la) and extend two-thirds of the distance il-ro. The latter do not reach the anterior limit of the aspis. The sensillus (Fig. 11B) is 70 µm long, narrow, membranous marginally and reminiscent of that of P. juvenalis. The tracheoles are short and finger-like. The notogaster (Fig. 11A) ranges in length from 314 - 517 µm with a greatest depth of 223 - 324 µm. All the setae are relatively long (equal to the distance c1 - d1), fine and almost erect. Setae c1 and c3 are situated on the posterior margin of the collar and just anterior to seta c2. Vestigial f1 is located a short distance posterior to seta h1. The fissures ip and ips are absent. On each anal plate there are only three setae; an1-2 being much longer than adj,. The chelicerae are 116- 167 µm long. The principal segment carries 9-23 sharply pointed spines on the paraxial surface and 8-20 conical spines antiaxially. The leg chaetotaxy is of the 'reduced type' with the setal formulae: I (1-3-2-5-15-1); II (1-3-2-3-11-1); III (2-2-1-2-10-1) and IV (2-1-0-2-9-1). On tarsus I seta u is short, thick and resembles a eupathidium. In one paratype the 'complete chaetotaxy' condition of tarsi I to IV (16, 12, 10 and 10) is associated with a 'reduced chaetotaxy' condition on femur I (3) and genu IV (0).</p> <p>Types: Holotype, BMNH reg. no. 1976.2.18.14, and two paratypes, 1976.2.18.15-16, from Sitka spruce F, Tintern Forest, Monmouthshire, 4.vi.73 (B. W. Parry).</p> <p>Distribution: P. membranifer was also recorded from Higher Kiln Quarry, Devon, 25.iv.64 (C. Moreby) and from Torboll, Sutherland, 29.vi.76 (P. D. Hillyard). This species was not abundant in any of the samples examined.</p> <p>Remarks: The smallest of the British species examined, P. membranifer is somewhat unusual in bearing vestigial f1 posterior to the seta h1 (a feature generally associated with the larger 'complete chaetotaxy' species).</p>Published as part of <i>Parry, B. W., 1979, A revision of the British species of the genus Phthiracarus Perty 1841 (Cryptostigmata: Euptyctima), pp. 323-363 in Bull. British Mus. nat. Hist., Zool. ser. 35</i> on pages 344-34
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