323,109 research outputs found
Dissection of genetic associations with language-related traits in population-based cohorts
No full textThe author was supported by the Wellcome Trust [076566/Z/05/Z]; [075491/Z/04] and the Medical Research Council [G0800523/86473].Recent advances in the field of language-related disorders have led to the identification of candidate genes for specific language impairment (SLI) and dyslexia. Replication studies have been conducted in independent samples including population-based cohorts, which can be characterised for a large number of relevant cognitive measures. The availability of a wide range of phenotypes allows us to not only identify the most suitable traits for replication of genetic association but also to refine the associated cognitive trait. In addition, it is possible to test for pleiotropic effects across multiple phenotypes which could explain the extensive comorbidity observed across SLI, dyslexia and other neurodevelopmental disorders. The availability of genome-wide genotype data for such cohorts will facilitate this kind of analysis but important issues, such as multiple test corrections, have to be taken into account considering that small effect sizes are expected to underlie such associations.Peer reviewe
Russkie frazeologičeskie sočetanija s suščestvitel’nymi, oboznačajuščimi otricatel’nye emocii. Sopostavitel’nyj analiz
No full textI meccanismi di suffissazione relativi alla formazione dei verbi nella lingua russa di Internet
No full textThe present work investigates the role of derivation for the development of lexical system in the Russian network. Specifically, it focuses on suffixation mechanisms that form verbal neologisms motivated by nouns. It describes the productivity of the different derivational models, their behaviour and underline the influence of new lexemes on the relation between semantics and structure of the phrase, highlighting some peculiarities of Russian language in the Internet
FAST AND RELIABLE FACIAL LANDMARKS LOCALIZATION IN NON FRONTAL IMAGES
No full textThe goal of this paper is to introduce a pipeline able to precisely and rapidly localize a set of facial landmarks on a face image. The proposed method is also able to estimate the pose of the face portrayed on the image independently from its orientation and it is robust to partial occlusions. This method is based on an optimized version of Part Mixture Model, it is able to fit a facial landmarks configuration to faces dealing with out-of-plane rotations and is suitable for real time processing. Moreover, the proposed method also uses a double scale approach to speed up the pose estimation phase and a posteriori configuration regularization based on Principal Component Analysis (PCA)
Visual Odometry from Omnidirectional Images for Intelligent Transportation
No full textIn this article we use omnidirectional images obtained from equirectangular panoramas of Google MapsTM to estimate camera egomotion. The systems was also tested using a 360 camera. The goal is to provide an effective and accurate positioning system for indoor environments or in urban canyons where GPS signal could be absent. We reformulated classical Computer Vision geometrical constraints for pin-hole cameras, like epipolar and trifocal tensor, to omnidirectional cameras obtaining new and effective equations to accurately reconstruct the camera path using couples or triplets of omnidirectional images. Tests have been performed on straight and curved paths to validate the presented approaches
Hematologic and biochemical variables of hedgehogs (Erinaceus europaeus) after overwintering in rehabilitation centers
No full textBackground: Information about laboratory reference intervals (RIs) of European Hedgehog (Erinaceus europaeus) hospitalized at rehabilitation centers is scarce. Objective: The purpose of this study was to establish hematologic and biochemical RIs for rehabilitated hedgehogs before the release into the wild, and to assess whether sex and management of the center influence laboratory results. Methods: Blood was collected from 50 hedgehogs at 3 centers. Thirty-eight animals were included in the study based on normal body weight, absence of clinical signs of disease, Bunnell index > 0.80, and absence of hibernation during overwintering. CBCs were performed using an automated laser cell counter followed by morphologic analysis of blood smears. Clinical biochemistry was performed using an automated spectrophotometer. RIs were determined as recommended by the ASVCP guidelines. Results: Hematology profiles revealed a prevalence of lymphocytes, a constant presence of nucleated RBCs, Howell-Jolly bodies and basophils, and bilobed nuclei in neutrophils and eosinophils. Biochemistry profiles were characterized by higher creatinine and urea concentrations, and higher ALP and GGT activities compared with other domestic species. The sex did not influence the results. Conversely, numbers of eosinophils, activated and large granular lymphocytes, and concentrations of total protein, glucose and cholesterol were different among the centers, likely due to different management practices (eg, antiparasitic treatments, environmental exposure to microorganisms, diet). Conclusion: The RIs established in this study can be used to monitor the health status of hedgehogs in rehabilitation centers. As management practices appeared to influence some variables, it is recommended to standardize the management protocols to minimize their influence on laboratory data
The hydrophilic spin trap, 5,5-dimethyl-1-pyrroline-1-oxide, does not protect the rat heart from reperfusion injury
No full textThe role and site of free radical generation in myocardial ischemia/reperfusion injury were investigated using the hydrophilic spin trapping agent, 5,5-dimethyl-1-pyrroline-1-oxide (DMPO). DMPO (40 mM) proved ineffective in preserving the contractile performance and energy metabolism of Langendorff-perfused rat hearts following ischemia and reperfusion. This result, which is in contrast with the cardioprotection observed with hydrophobic spin traps, suggests that free radicals are generated intracellularly under these conditions
Eosinophilic oesophagitis in children. Long term follow up and behavior of peripheral eosinophils’ count
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