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    Forest plot of the meta-analysis of fibrate use and cancer deaths.

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    <p>Footnote: The risk ratios and their 95% confidence intervals are displayed on a logarithmic scale. The size of the data markers represents the relative weight of the trial according to size and occurrence of the outcome being measured.</p

    Characteristics of studies included in the meta-analysis.

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    <p>Abbreviations: ACCORD, Action to Control Cardiovascular Risk in Diabetes; BECAIT, Bezafibrate Coronary Atherosclerosis Intervention Trial; BIP, Bezafibrate Infarction Prevention; CDP, Coronary Drug Project; DAIS, Diabetes Atherosclerosis Intervention Study; DIS, Diabetes Intervention Study; FIELD, Fenofibrate Intervention and Event Lowering in Diabetes; HHS, Helsinki Heart Study; LEADER, Lower Extremity Arterial Disease Event Reduction; LOCAT, Lopid Coronary Angiography Trial; SENDCAP, St. Mary’s, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention; VA HIT, Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial; WHO, World Health Organization; r, randomized; db, double-blind; pc, placebo-controlled; DM, Diabetes Mellitus; CAD, Coronary Artery Disease; NIDDM, Non-Insulin-Dependent Diabetes Mellitus; LEAD, Lower Extremity Arterial Disease.</p

    Incidence of and/or deaths from cancer in the randomized placebo-controlled trials of fibrates.

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    *<p>Crude rates;</p>**<p>Reported in Saha et al. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045259#pone.0045259-Saha1" target="_blank">[43]</a>.</p><p>Abbreviations: ACCORD, Action to Control Cardiovascular Risk in Diabetes; BECAIT, Bezafibrate Coronary Atherosclerosis Intervention Trial; BIP, Bezafibrate Infarction Prevention; CDP, Coronary Drug Project; DAIS, Diabetes Atherosclerosis Intervention Study; DIS, Diabetes Intervention Study; FIELD, Fenofibrate Intervention and Event Lowering in Diabetes; HHS, Helsinki Heart Study; LEADER, Lower Extremity Arterial Disease Event Reduction; LOCAT, Lopid Coronary Angiography Trial; SENDCAP, St. Mary’s, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention; VA HIT, Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial; WHO, World Health Organization; RR, relative risk (risk ratio); CI, confidence interval.</p

    Flow Diagram.

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    <p>Footnote: * To be included in this meta-analysis, studies had to be (i) randomized trials of fibrates, (ii) placebo-controlled, and (iii) have a mean (or median) duration of patient follow-up of at least 2 years.</p

    Meta-regression’s results.

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    <p>RR, risk ratio; CI, confidence interval.</p><p>Results are exponentiated regression coefficients and their 95% CIs, which show the proportional change in risk ratio for every one scale increase.</p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Forest plot of the meta-analysis of fibrate use and cancer incidence.

    No full text
    <p>Footnote: The risk ratios and their 95% confidence intervals are displayed on a logarithmic scale. The size of the data markers represents the relative weight of the trial according to size and occurrence of the outcome being measured.</p
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