130,617 research outputs found
Interessi superindividuali e giudice amministrativo. Brevi riflessioni a margine di Ad. plen. 6/2020, pensando all'"ambiente" delle generazioni presenti e future
No full textCigarette smoking and musculoskeletal disorders.
No full textCigarette smoking has deleterious effects on the musculo-skeletal system. The loss of bone mineral content and increased incidence of fractures are the best known negative consequences. The pathogenesis is complex, due to direct toxic effects on osteoblasts/osteoclasts activity of nicotine, and indirect actions on sex and adrenocortical hormones, vitamin D, intestinal calcium absorption, vessels and oxygen supply. Smoking may favour the onset or aggravate the progression of rheumatoid arthritis and back pain. Negative influences have been observed on muscle and on tendons. Moreover, smoking habit is associated to a number of short term post-operative complications and higher resource consumption. Smoking cessation is highly advisable with positive effects on the bone metabolism on the long term. More positive and immediate results can be obtained in patients submitted to orthopedic surgery: the healing process is improved, the frequency of complications is reduced, and the length of hospital stay is shortened
Cigarette smoking and musculoskeletal disorders
No full textCigarette smoking has deleterious effects on the musculo-skeletal system. The loss of bone mineral content and increased incidence of fractures are the best known negative consequences. The pathogenesis is complex, due to direct toxic effects on
osteoblasts/osteoclasts activity of nicotine, and indirect actions on sex and adrenocortical hormones, vitamin D, intestinal calcium absorption, vessels and oxygen supply. Smoking may favour the onset or aggravate the progression of rheumatoid arthritis and back pain. Negative influences have been observed on muscle and on tendons. Moreover, smoking habit is associated to a number of short term post-operative complications and higher resource consumption.
Smoking cessation is highly advisable with positive effects on the bone metabolism on the long term. More positive and immediate results can be obtained in patients submitted to orthopedic surgery: the healing process is improved, the frequency of complications is reduced, and the length of hospital stay is shortene
Outcome of treatment for pelvic ring and acetabulum fractures: Personal experience [Trattamento delle fratture dell'anello pelvico e dell'acetabolo: Esperienza personale]
No full textAim. Pelvic ring and acetabulum fractures are usually due to a high-energy transfer. These trauma convey high mortality and morbidity. They require a multidisciplinary approach and a right pre- and postoperative management. The aim of this study was to evaluate the results about the treatment of pelvic fractures treated by open reduction and internal fixation. Methods. A retrospective study was performed on 34 patients (mean age 37 years) treated for pelvic fracture between January 2008 and May 2011, at the Orthopedic and Traumatology Department of Chieti. The fractures were classified according to Tile (pelvic ring) and Judet and Letournel (acetabulum). The mean follow-up, clinical and radiographic, according to "Matta Radiographic Score" and "Majeed Pelvic Score" lasts from 12 to 40 months (mean follow-up 24 months). Results. All patients were treated within five days after injury (2.9 days on average). The radiographic score was excellent in 61.7% of cases, good in 32.5% and fair in 5.8%. The final clinical outcome was excellent in 21 patients, good in 11 and poor in two. according to the "Majeed Pelvic Score". Conclusion. Surgical treatment of dislocated acetabular fractures requires an open reduction and a stable internal fixation. Excellent and good results can be expected only if anatomical reduction and stable internal fixation are achieved
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
CLINICAL EFFICACY AND SAFETY OF NEOIAL HC (HYALURONIC ACID + COLLAGEN) FOR INTRA-ARTICULAR USE IN THE TREATMENT OF SEVERE KNEE OSTEOARTHRITIS
No full text"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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