1,720,985 research outputs found
BRAIN COLECYSTOKININ AND BETA ENDORPHIN IMMUNO-REACTIVITY IN RATS WITH DIFFERENT EXPERIMENTAL MODELS OF LIVER FAILURE
Mainly mu-opiate receptors are involved in luteinizing hormone and prolactin secretion.
We evaluated plasma PRL and LH concentrations in the rat after the administration of drugs that exert a specificity directed mainly, although not absolutely, toward the mu-, delta-, or kappa-opiate receptors, in order to investigate the role of different receptors and thus the respective endogenous ligands in the modulation of the release of these anterior pituitary hormones. LH concentrations were evaluated in prepuberal female rats, in adult male rats, and in ovariectomized, estradiol benzoate-treated rats. PRL concentrations were evaluated in suckling rats, in ovariectomized, estradiol benzoate-treated rats, and in ether-stressed rats. The delta-antagonist ICI 154129 never affected PRL or LH concentrations, whereas both the mu- and kappa-antagonists, naloxone and MR 1452, respectively, seemed to be effective. However, when graded doses of the two classes of antagonists were tested, the mu-antagonist appeared to be effective on both hormones at doses that were one tenth of those of the kappa-antagonist. In conclusion, the mu-receptor seems to be the most profoundly involved in the regulation of PRL and LH secretion
The nonpsychoactive component of marijuana cannabidiol modulates chemotaxis and IL-10 and IL-12 production of murine macrophages both in vivo and in vitro.
Therapeutic perspective of murine adult neuronal and human mesenchymal stem cell transplantation in neuropathic pain
A new model of chronic psychosocial stress in mice: behavioral, endocrine, immune and cardiovascular correlates
Individual housing induce altered immuno-endocrine responses to psychological stress in male mice
beta endorphin concentrations in PBMC of patients with different clinical phenotypes of multiple sclerosis
beta-endorphin concentrations in peripheral blood mononuclear cells of patients with multiple sclerosis - Effects of treatment with interferon beta
- …
