112 research outputs found

    <i>In vivo</i>diabetic wound healing with nanofibrous scaffolds modified with gentamicin and recombinant human epidermal growth factor

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    Diabetic wounds are susceptible to microbial infection. The treatment of these wounds requires a higher payload of growth factors. With this in mind, the strategy for this study was to utilize a novel payload comprising of Eudragit RL/RS 100 nanofibers carrying the bacterial inhibitor gentamicin sulfate (GS) in concert with recombinant human epidermal growth factor (rhEGF); an accelerator of wound healing. GS containing Eudragit was electrospun to yield nanofiber scaffolds, which were further modified by covalent immobilization of rhEGF to their surface. This novel fabricated nanoscaffold was characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction. The thermal behavior of the nanoscaffold was determined using thermogravimetric analysis and differential scanning calorimetry. In the in vitro antibacterial assays, the nanoscaffolds exhibited comparable antibacterial activity to pure gentemicin powder. In vivo work using female C57/BL6 mice, the nanoscaffolds induced faster wound healing activity in dorsal wounds compared to the control. The paradigm in this study presents a robust in vivo model to enhance the applicability of drug delivery systems in wound healing applications. (c) 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 641-651, 2018

    Medical data security for bioengineers Advances in bioinformatics and biomedical engineering book series./ Butta Singh, Barjinder Singh Saini, Dilbag Singh, Anukul Pandey, [editors].

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    Includes bibliographical references."This book examines the issues facing medical data security in healthcare systems and applications. It also explores the advancements in engineering applications to healthcare technologies, biomedical information security and data privacy, and cloud computing technologies in healthcare"--Provided by publisherAdvancements in data security and privacy techniques used in IoT based hospital applications / Ankita Tiwari, Raghuvendra Tripathi -- Engineering solutions for the future of modern medicine / Surendar Aravindhan, Kavitha M, Synthesishub -- Optimization techniques for the multilevel thresholding of the medical images / Taranjit Kaur, Barjinder Saini -- Bernoulli's chaotic map based 2D ECG image steganography : a medical data security approach / Anukul Pandey, Barjinder Saini, Butta Singh, Neetu Sood -- Cloud computing technologies in healthcare : importance of cloud in e-healthcare / R. Suganya, Sujatha S. -- Techniques for biomedical data security / Harminder Kaur, Sharvan Kumar Pahuja -- An IWT based blend of cryptography and steganography for securing confidential data in biomedical signals / Neetika Soni, D. Indu Saini, Butta Singh -- Changes in physiological dynamics of EEG during meditation using Wavelet families / Neha Gupta -- Compression of biomedical images using compressive sensing / Meenakshi Sood, Charu, Urvashi, Shruti Jain -- Electrocardiogram beat classification using BAT optimized fuzzy KNN classifier / Atul Kumar Verma, Indu Saini, Barjinder Singh Saini.1 online resourc

    Cyber-Physical Co-Simulation Testbed for Real-Time Reactive Power Control in Smart Distribution Network

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    Existing electric power distribution systems are evolving and changing as a result of the high renewable energy sources integration. Hence, future smart distribution networks will involve various technical challenges; one of them is real-time monitoring and controlling the network to operate it effectively and efficiently. This paper develops and analyzes a cyber-physical co-simulation testbed for real-time reactive power control in the smart distribution network. The testbed is a two-layer system, with Typhoon HIL 604 representing the physical layer and the other layer as a cybernetic layer. The cybernetic layer is used to model a test system and control reactive power from smart inverters in real-time. The implementation of real-time reactive power control of smart inverters on a CIGRE MV distribution network is shown in this study. The proposed testbed's usefulness in real-time reactive power control is demonstrated through simulation results.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Intelligent Electrical Power Grid

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    Screening for Hemoglobinopathy

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    Author Index August 2024

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