263 research outputs found
sj-docx-1-dhj-10.1177_20552076231176653 - Supplemental material for Kinect-based objective evaluation of bradykinesia in patients with Parkinson's disease
Supplemental material, sj-docx-1-dhj-10.1177_20552076231176653 for Kinect-based objective evaluation of bradykinesia in patients with Parkinson's disease by Zhuang Wu, Hongkai Gu, Ronghua Hong, Ziwen Xing, Zhuoyu Zhang, Kangwen Peng, Yijing He, Ludi Xie, Jingxing Zhang, Yichen Gao, Yue Jin, Xiaoyun Su, Hongping Zhi, Qiang Guan, Lizhen Pan and Lingjing Jin in DIGITAL HEALTH</p
Critical Analyse of the Exceptions in Resorting to Restorative Justice When Children Come into Conflict with the Law
As the child justice system continues to evolve and the development of Children’s rights, there is a growing recognition of the need to address child offenders differently from adult offenders. Restorative justice has emerged as a promising approach to address the unique needs and circumstances of juvenile offenders, aiming to rehabilitate rather than solely punish. However, this research delves into the limitations and exceptions that may hinder the application of restorative justice in cases involving child offenders. The primary objective is to analyse the factors that influence the decision to deviate from restorative justice principles in children cases, which includes the severity of the offense; the age, maturity and attitude for guilty of the child; the times of committing offences of the child; the victim's perspective, and legal frameworks. By exploring these exceptions, the study aims to provide insights into the challenges and complexities that arise when applying restorative justice in child justice systems. Furthermore, the research employs a qualitative approach, involving a thorough review of legal provisions, case studies, and relevant literature to critically analyse the nuances of exceptions in restorative justice for children in conflict with the law. The findings contribute to the ongoing discourse surrounding the appropriate and effective use of restorative justice in juvenile cases, shedding light on when and why exceptions may be necessary. Ultimately, this paper serves as a valuable resource for policymakers, law enforcement officers, and researchers in the field of juvenile justice, offering a deeper understanding of the complexities inherent in implementing restorative justice in the child justice system
Development of a Risk Prediction Model for Infection After Kidney Transplantation Transmitted from Bacterial Contaminated Preservation Solution
Mingxing Guo,1,* Chen Pan,1,* Ying Zhao,1 Wanyi Xu,1 Ye Xu,1 Dandan Li,1 Yichen Zhu,2 Xiangli Cui1 1Department of Pharmacy, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiangli Cui, Department of Pharmacy, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China, Email [email protected] Yichen Zhu, Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China, Email [email protected]: The risk of transplant recipient infection is unknown when the preservation solution culture is positive.Methods: We developed a prediction model to evaluate the infection in kidney transplant recipients within microbial contaminated preservation solution. Univariate logistic regression was utilized to identify risk factors for infection. Both stepwise selection with Akaike information criterion (AIC) was used to identify variables for multivariate logistic regression. Selected variables were incorporated in the nomograms to predict the probability of infection for kidney transplant recipients with microbial contaminated preservation solution.Results: Age, preoperative creatinine, ESKAPE, PCT, hemofiltration, and sirolimus had a strongest association with infection risk, and a nomogram was established with an AUC value of 0.72 (95% confidence interval, 0.64– 0.80) and Brier index 0.20 (95% confidence interval, 0.18– 0.23). Finally, we found that when the infection probability was between 20% and 80%, the model oriented antibiotic strategy should have higher net benefits than the default strategy using decision curve analysis.Conclusion: Our study developed and validated a risk prediction model for evaluating the infection of microbial contaminated preservation solutions in kidney transplant recipients and demonstrated good net benefits when the total infection probability was between 20% and 80%.Keywords: risk prediction model, kidney transplant, nomogram, risk factor
Raw Data for "On-demand cell-autonomous gene therapy for brain circuit disorders", Qiu et al. 2022 Science
Raw Data for Qui et al. 2022 10.1126/science.abq6656
On-demand cell-autonomous gene therapy for brain circuit disorders
Yichen Qiu, Nathanael O’Neill, Benito Maffei, Clara Zourray, Amanda Almacellas Barbanoj, Jenna C. Carpenter,Steffan P. Jones, Marco Leite, Thomas J. Turner, Francisco C. Moreira, Albert Snowball, Tawfeeq Shekh-Ahmad, Vincent Magloire, Serena Barral, Manju A. Kurian, Matthew C. Walker, Stephanie Schorge, Dimitri M. Kullmann, Gabriele Lignani
Content:
EEG
MEA
Immuno
Patch Clamp Electrophysiology
All data are in a open source format. MEA files can be analysed using the MATLAB-based developed by Prof Michela Chiappalone and requests should be direct to:
Michela Chiappalone [email protected]
Ilaria Colombi [email protected]
EEG files are .zip with different transmitters. See EEG_Keys.xlxs for whcih virus was used in each animal.
MEA files are divided in 2 separate .zip: 1. Fig2 and Fig S3 and S7. 2. Fig S6.
Immuno: all the raw images are in the .zip file seprated by Figure #
Patch Clamp Electrophysiology: all the raw .abf files are in the .zip file separated by Figure #
For more info or to request materials please contact the corrsponding author Gabriele Lignani [email protected]
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What Is an Author's Role in the AI Era? Demystifying the Black Box of Human-AI Collaborative Creation Through an "Aesthetic Judgment" Study of the novel Solid Reference Frame Manuscript
This project repository establishes a permanent timestamp for a study that rethinks Roland Barthes' proclamation of the "death of the author" for the AI era. It engages with Michel Foucault's concept of "author-function" to propose "Aesthetic Judgment" as a new theoretical framework for human-AI collaborative creation. This framework reconceptualizes AI as a "critical partner"—a source of provocation and challenge. The human author, in turn, exercises decisive curatorial power through four key operations: 1) The Right to Question, 2) The Right to Select, 3) The Right to Arbitrate, and 4) The Right to Integrate.
Employing a "Process-Tracing" methodology, the research analyzes the complete manuscript of the novel Solid Reference Frame to demystify the creative "black box." This empirical study aims to demonstrate how the human author's role is transformed from a solitary genius into a systemic architect of meaning, thereby asserting a new, viable author-function for the digital age
Tailored family adaptation to living in a zero-energy house: Occupant’s crises and conflicts with a heat pump-based system
BackgroundThis project belongs to the IEBB project, which advocates for the renovation of ‘zero energy houses’ (ZEH) that synergize insulation and heat pump systems for energy conservation. The ZEH’s energy-saving efficiency depends on user behaviour. From a systems perspective, improper human interactions hinder energy saving, while occupants may find system responses that conflict with their preferences. This study delves into these conflicts and crises, highlighting the variance in post-occupancy adaptation influenced by individual perceptions and familial interplay. The project’s zenith aim is to tailor adaptation, ensuring co-performance between the heat pumpsystem and households. Key InsightIn researching residents’ responses to the ‘routine crisis’ introduced by a new system, I discovered that these ‘crises’ could be productive, stimulating household engagement and fostering harmonious interactions with ZEH systems. This insight gave rise to the concept of the ‘enacted interface’ - a distinctive bridge between residents and their automated homes that supports the adaptation process. Through analysis, I identified elements that amplify residents’ engagement with ‘crises’ and observed the influence of family diversity on individual perceptions and responses to them. The results are manifested in two interrelated frameworks: one describing the ubiquity of ‘crises’ and another characterising the classification and impact of different elements.DesignThis design aims to make households curious about ‘crises’ and guide them towards tailored adaptations to new tech. The ‘Clock’ thermostat provides a consistent interface for temperature adjustments, while the ‘Feeling Message Board’ suggests lifestyle tips based on the user’s emotional input and changing scenarios. Both reinforce the system’s ability to communicate contextual and real-time status, motivating users to actively engage with its functions. Additionally, the design stimulates family discussions about the indoor environment and promotes collaborative responses to ‘crises’. Through co-performance of the system’s dynamic feedback and the household’s proactive exploration, the aim is to facilitate tailored adaptation.IEBB projectIntegrated Product Desig
Design and Implementation of Intelligent Home Power Control Systems by Using Raspberry Pi and AWS Cloud Service
The Influence of Gender Matching and Result Feedback on University Students Cooperative Behavior
Research on Solutions of Vocational School Students to Employment Pressure under the Perspective of Psychological Elasticity
Contact of the incisive canal and upper central incisors causing root resorption after retraction with orthodontic mini-implants: A CBCT study
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