1,720,984 research outputs found
Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma: focus on immunohistochemical profile and association with Epstein-Barr virus
No full textInflammatory pseudotumour-like follicular/fibroblastic dendritic cell sarcoma (IPT-like FDCS) is a rare EBV-associated variant of follicular dendritic cell sarcoma, usually arising in the liver or spleen and characterized by a favourable prognosis. The neoplastic cells show variable follicular dendritic cell or fibroblastic reticular cell differentiation and their immunoprofile is still poorly characterized. We describe a case of splenic IPT-like FDCS with unexpected CD31 expression and provide a concise review of English literature on the topic
Longstanding Eccrine Syringofibroadenoma With Evidence of Carcinomatous Transformation
No full textEccrine syringofibroadenoma (ESFA) is a cutaneous proliferation of eccrine ducts, mainly encountered in association with other dermatoses or skin tumors. Although a benign condition, either considered as a hamartoma or a reactive hyperplasia rather than a real neoplasm, some evidence suggests that longstanding ESFA can undergo malignant change. The recognition of such opportunity could have important therapeutic implications. We present a case of ESFA showing areas of carcinomatous transformation, discussing its morphological and immunohistochemical findings
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Cardiovascular Diseases in Public Health: Chromosomal Abnormalities in Congenital Heart Disease Causing Sudden Cardiac Death in Children
No full textPalmoplantar psoriasis or palmoplantar keratoderma? Successful treatment with brodalumab
No full textUnusual Nodule on the Left Leg of an Elderly Woman—A Case Report: Challenge
No full textWe present the case of a 71-year-old woman with no significant medical history who developed a nodular, ulcerated lesion on her left leg, alongside bruise-like lesions on her extremities. Histologic examination revealed basal cell carcinoma with adenoid-cystic features colliding with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare and aggressive hematologic malignancy. Immunohistochemical analysis confirmed BPDCN, with markers such as CD123, CD4, CD56, and TCL1, and a high proliferation index (Ki67 >90%). This represents the first reported case of a collision lesion comprising adenoid-cystic basal cell carcinoma and BPDCN. The findings highlight the need for comprehensive histopathologic evaluation in atypical cases to achieve an accurate diagnosis
Multicentral meningothelial meningioma: A case of death
No full textMeningiomas are intracranial tumors originating from arachnoidal cells. Multiple intracranial meningiomas are rare and occur when two or more lesions occur either simultaneously or sequentially in different locations. We described a case of multiple meningothelial meningioma post forensic autopsy
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