1,721,083 research outputs found
The Strategic Limits of Legal Development
Get PDFU prvom dijelu članka autor se osvrće na knjigu obećavajućeg naslova "Pravo i revolucija" i još više obećavajućeg sadržaja za one koji su skloni da o pravu razmišljaju strategijski. Polazeći od glavnih teza te knjige i nekih interpretacija pravne povijesti koje se teze kvalificiraju, u završnom dijelu pokazuje da su mogućnosti strategijskog djelovanja u obnovi i razvoju hrvatskog prava zanemarivo male.In the first part of his paper the author looks at a book with the promising title "Law and Revolution", promising in particular to those prone to think about law strategically. Starting from the main points of the book and of some interpretations of legal history that qualify these points, the author, in the final part, demonstrates how negligible appear to be the possibilities of a strategic action in the renewal and development of Croatian law
Cryoglobulinemia in patients with systemic autoimmune diseases
No full textUvod: Krioglobulini su proteini koji precipitiraju pri temperaturi ispod 37°C, a njihova prisutnost u serumu zove se krioglobulinemija. Tip 1 krioglobulinemije veže se uz limfoproliferativne bolesti, dok se tipovi krioglobulinemije 2 i 3 povezuju s infekcijom virusom hepatitisa C, neoplazmama te sustavnim autoimunim bolestima.
Ciljevi: Cilj ovog istraživanja je usporediti laboratorijske i kliničke značajke između bolesnika s krioglobulinemijom tipa 2 i tipa 3.
Ispitanici i metode: Riječ je o presječnoj studiji temeljenoj na podacima iz bolničke arhive. Uključeni su bolesnici kojima je u razdoblju od tri godine dokazana prisutnost krioglobulina u serumu. Analizirana su klinička i laboratorijska obilježja koja su zatim uspoređena između bolesnika s krioglobulinemijom tipa 2 i 3.
Rezultati: Prisutnost krioglobulina dokazana je kod ukupno 38 bolesnika (krioglobulinemija tip 2 – 10 bolesnica; krioglobulinemija tip 3 – 24 bolesnice i 4 bolesnika). Kod bolesnika s krioglobulinemijom tipa 2 pronađena je značajno viša vrijednost reumatoidnog faktora (359,9, IKR 106,6-379,5 IU/ml vs. 20, IKR 13,4-93,4 IU/ml, p=0,007) i krioprecipitata (385,5, IKR 216,5-492,5 mg/L vs. 119,5, IKR 82,3-156 mg/L, p<0,001) te niža vrijednost C4 (0,04, IKR 0,03-0,08 g/L vs. 0,13, IKR 0,06-0,19 g/L, p=0,025) i gama globulina (9,3, IKR 8,1-12,2 g/L vs. 12,5, IKR 9,6-19 g/L, p=0,029) u usporedbi sa bolesnicima s krioglobulinemijom tipa 3. Dijagnoza SLE-a postavljena je kod 21 bolesnika (tip 2 - 8 bolesnika vs. tip 3 - 13 bolesnika, p=0,137). Dijagnoza Sjögrenovog sindroma utvrđena je kod 8 bolesnika (tip 2 - 6 bolesnika vs. tip 3 - 2 bolesnika, p=0,002).
Zaključak: U analiziranoj skupini bolesnika najčešće su prisutne dijagnoze Sjögrenovog sindroma i SLE-a. Dijagnoza krioglobulinemije tipa 2 rjeđa je od krioglobulinemije tipa 3, a povezana je sa Sjögrenovim sindromom i izraženijim utroškom komplementa.Introduction: Cryoglobulins are proteins that precipitate at the temperature below 37°C, and their presence in the serum is called cryoglobulinemia. Cryoglobulinemia type 1 is associated with lympfoproliferative disorders, while cryoglobulinemia types 2 and 3 are associated with hepatitis C infection, neoplasms and systemic autoimmune diseases.
Aim: The aim of this study was to compare laboratory and clinical features between patients with cryoglobulinemia type 2 and 3.
Patients and methods: For this cross-sectional study data were obtained from the hospital archives. Patients positive for cryoglobulinemia in their serum over a period of three years were included in the study. Clinical and laboratory characteristics were analyzed and then compared between patients with cryoglobulinemia type 2 and 3.
Results: The presence of cryoglobulin was proven in a total of 38 patients (cryoglobulinemia type 2 – 10 female patients; cryoglobulinemia type 3 – 24 female patients and 4 male patients). In patients with cryoglobulinemia type 2, we identified a significantly higher value of rheumatoid factor (359.9, IQR 106.6-379.5 IU/ml vs. 20, IQR 13.4-93.4 IU/ml, p=0.007) and cryoprecipitate (385.5, IQR 216.5-492.5 mg/L vs. 119.5, IQR 82,3-156 mg/L, p<0.001), and a lower value of C4 (0.04, IQR 0.03-0.08 g/L vs. 0.13, IQR 0,06-0,19 g/L, p=0.025) and gamma globulin (9.3 , IQR 8.1-12.2 g/L vs. 12.5, IQR 9.6-19 g/L, p=0.029) compared to patients with cryoglobulinemia type 3. The diagnosis of SLE was made in 21 patients (type 2 - 8 patients vs. type 3 - 13 patients, p=0.137). the diagnosis of Sjögren's syndrome was established in 8 patients (type 2 - 6 patients vs. type 3 - 2 patients, p=0.002)
Conclusion: In the analyzed group of patients, the most common diagnoses were Sjögren's syndrome and SLE. The diagnosis of cryoglobulinemia type 2 was less common than cryoglobulinemia type 3, and it was associated with Sjögren's syndrome and a more pronounced hypocomplementemia
Application of the SLERPI scoring system as a classification criteria for systemic lupus erythematosus and its predictive value for disease recognition
No full textUvod: Sustavni eritemski lupus (SLE) je kronična, multisistemska, autoimunosna bolest s heterogenom kliničkom slikom što uz nepostojanje dijagnostičkih kriterija otežava rano prepoznavanje bolesti. SLERPI (engl. Systemic Lupus Erythematosus Risk Probability Index) je bodovni sustav napravljen pomoću strojnog učenja za pomoć pri dijagnozi SLE-a.
Cilj rada: Ispitati performanse SLERPI-a kao klasifikacijskog kriterija i prediktivnog indeksa za rano prepoznavanje bolesti.
Metode: U presječno istraživanje uključeno je 54 bolesnika sa SLE-om i 54 bolesnika s drugim upalnim reumatskim bolestima, svi s pozitivnim nalazom antinuklearnih protutijela (ANA). Analizirani su podaci iz medicinske dokumentacije prikupljeni u dvije vremenske točke – pri prvom pregledu i kumulativno. Analizirane su performanse SLERPI-a i kriterija ACR/EULAR-a iz 2019. godine u obje vremenske točke te evaluirane različite granične vrijednosti pozitiviteta SLERPI-a.
Rezultati: SLERPI je u obje vremenske točke pokazao usporedive performanse s kriterijima ACR/EULAR-a uz nešto veću osjetljivost (prvi pregled: 85,2% vs. 79,6%; kumulativno 98,1% vs. 96,3%) i nižu specifičnost (prvi pregled: 68,5% vs. 70,4%; kumulativno 53,7% vs. 55,6%). Analiza je pokazala numerički veću površinu ispod ROC krivulje za SLERPI u obje vremenske točke u odnosu na kriterije ACR/EULAR-a. Povišenjem granične vrijednosti pozitiviteta (sa >7 na >7,5 ili >8), poboljšane su performanse SLERPI-a.
Zaključak: SLERPI pokazuje vrlo dobre dijagnostičke performanse, osobito pri prvom pregledu, uz nešto viši iznos osjetljivosti i niži iznos specifičnosti u odnosu na kriterije ACR/EULAR-a. Može predstavljati korisno pomoćno sredstvo u ranoj identifikaciji SLE-a, posebice u ANA- pozitivnih bolesnika, kod kojih se za veću učinkovitost distinkcije može razmotriti viša granična vrijednost pozitiviteta.Introduction: Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease with a heterogeneous clinical presentation, which, combined with the absence of diagnostic criteria, complicates early disease recognition. SLERPI (Systemic Lupus Erythematosus Risk Probability Index) is a scoring system developed using machine learning to assist in the diagnosis of SLE.
Aim: To evaluate the performance of SLERPI as a classification tool and its predictive value for early disease recognition.
Methods: We conducted a cross-sectional study involving 54 patients with SLE and 54 patients with other inflammatory rheumatic diseases, all positive for antinuclear antibodies (ANA). Data from medical records were analysed at two time points — at the initial examination and cumulatively. The performance of SLERPI and the 2019 ACR/EULAR criteria were analysed at both time points, and different positivity thresholds for SLERPI were evaluated.
Results: SLERPI demonstrated comparable performance to the ACR/EULAR criteria at both time points, with slightly higher sensitivity (initially: 85.2% vs. 79.6%; cumulatively: 98.1% vs. 96.3%) and lower specificity (initially: 68.5% vs. 70.4%; cumulatively: 53.7% vs. 55.6%). Analysis showed a numerically larger area under the ROC curve for SLERPI at both time points compared to the ACR/EULAR criteria. Increasing the positivity threshold (from >7 to >7.5 or >8) improved the performance of SLERPI.
Conclusion: SLERPI demonstrated a solid diagnostic performance, especially at the initial examination, with somewhat higher sensitivity and lower specificity compared to the ACR/EULAR criteria. It may represent a useful adjunct tool for early identification of SLE, particularly in ANA-positive patients, where a higher positivity threshold could be employed to enhance discriminatory effectiveness
Application of the SLERPI scoring system as a classification criteria for systemic lupus erythematosus and its predictive value for disease recognition
No full textUvod: Sustavni eritemski lupus (SLE) je kronična, multisistemska, autoimunosna bolest s heterogenom kliničkom slikom što uz nepostojanje dijagnostičkih kriterija otežava rano prepoznavanje bolesti. SLERPI (engl. Systemic Lupus Erythematosus Risk Probability Index) je bodovni sustav napravljen pomoću strojnog učenja za pomoć pri dijagnozi SLE-a.
Cilj rada: Ispitati performanse SLERPI-a kao klasifikacijskog kriterija i prediktivnog indeksa za rano prepoznavanje bolesti.
Metode: U presječno istraživanje uključeno je 54 bolesnika sa SLE-om i 54 bolesnika s drugim upalnim reumatskim bolestima, svi s pozitivnim nalazom antinuklearnih protutijela (ANA). Analizirani su podaci iz medicinske dokumentacije prikupljeni u dvije vremenske točke – pri prvom pregledu i kumulativno. Analizirane su performanse SLERPI-a i kriterija ACR/EULAR-a iz 2019. godine u obje vremenske točke te evaluirane različite granične vrijednosti pozitiviteta SLERPI-a.
Rezultati: SLERPI je u obje vremenske točke pokazao usporedive performanse s kriterijima ACR/EULAR-a uz nešto veću osjetljivost (prvi pregled: 85,2% vs. 79,6%; kumulativno 98,1% vs. 96,3%) i nižu specifičnost (prvi pregled: 68,5% vs. 70,4%; kumulativno 53,7% vs. 55,6%). Analiza je pokazala numerički veću površinu ispod ROC krivulje za SLERPI u obje vremenske točke u odnosu na kriterije ACR/EULAR-a. Povišenjem granične vrijednosti pozitiviteta (sa >7 na >7,5 ili >8), poboljšane su performanse SLERPI-a.
Zaključak: SLERPI pokazuje vrlo dobre dijagnostičke performanse, osobito pri prvom pregledu, uz nešto viši iznos osjetljivosti i niži iznos specifičnosti u odnosu na kriterije ACR/EULAR-a. Može predstavljati korisno pomoćno sredstvo u ranoj identifikaciji SLE-a, posebice u ANA- pozitivnih bolesnika, kod kojih se za veću učinkovitost distinkcije može razmotriti viša granična vrijednost pozitiviteta.Introduction: Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease with a heterogeneous clinical presentation, which, combined with the absence of diagnostic criteria, complicates early disease recognition. SLERPI (Systemic Lupus Erythematosus Risk Probability Index) is a scoring system developed using machine learning to assist in the diagnosis of SLE.
Aim: To evaluate the performance of SLERPI as a classification tool and its predictive value for early disease recognition.
Methods: We conducted a cross-sectional study involving 54 patients with SLE and 54 patients with other inflammatory rheumatic diseases, all positive for antinuclear antibodies (ANA). Data from medical records were analysed at two time points — at the initial examination and cumulatively. The performance of SLERPI and the 2019 ACR/EULAR criteria were analysed at both time points, and different positivity thresholds for SLERPI were evaluated.
Results: SLERPI demonstrated comparable performance to the ACR/EULAR criteria at both time points, with slightly higher sensitivity (initially: 85.2% vs. 79.6%; cumulatively: 98.1% vs. 96.3%) and lower specificity (initially: 68.5% vs. 70.4%; cumulatively: 53.7% vs. 55.6%). Analysis showed a numerically larger area under the ROC curve for SLERPI at both time points compared to the ACR/EULAR criteria. Increasing the positivity threshold (from >7 to >7.5 or >8) improved the performance of SLERPI.
Conclusion: SLERPI demonstrated a solid diagnostic performance, especially at the initial examination, with somewhat higher sensitivity and lower specificity compared to the ACR/EULAR criteria. It may represent a useful adjunct tool for early identification of SLE, particularly in ANA-positive patients, where a higher positivity threshold could be employed to enhance discriminatory effectiveness
Cryoglobulinemia in patients with systemic autoimmune diseases
No full textUvod: Krioglobulini su proteini koji precipitiraju pri temperaturi ispod 37°C, a njihova prisutnost u serumu zove se krioglobulinemija. Tip 1 krioglobulinemije veže se uz limfoproliferativne bolesti, dok se tipovi krioglobulinemije 2 i 3 povezuju s infekcijom virusom hepatitisa C, neoplazmama te sustavnim autoimunim bolestima.
Ciljevi: Cilj ovog istraživanja je usporediti laboratorijske i kliničke značajke između bolesnika s krioglobulinemijom tipa 2 i tipa 3.
Ispitanici i metode: Riječ je o presječnoj studiji temeljenoj na podacima iz bolničke arhive. Uključeni su bolesnici kojima je u razdoblju od tri godine dokazana prisutnost krioglobulina u serumu. Analizirana su klinička i laboratorijska obilježja koja su zatim uspoređena između bolesnika s krioglobulinemijom tipa 2 i 3.
Rezultati: Prisutnost krioglobulina dokazana je kod ukupno 38 bolesnika (krioglobulinemija tip 2 – 10 bolesnica; krioglobulinemija tip 3 – 24 bolesnice i 4 bolesnika). Kod bolesnika s krioglobulinemijom tipa 2 pronađena je značajno viša vrijednost reumatoidnog faktora (359,9, IKR 106,6-379,5 IU/ml vs. 20, IKR 13,4-93,4 IU/ml, p=0,007) i krioprecipitata (385,5, IKR 216,5-492,5 mg/L vs. 119,5, IKR 82,3-156 mg/L, p<0,001) te niža vrijednost C4 (0,04, IKR 0,03-0,08 g/L vs. 0,13, IKR 0,06-0,19 g/L, p=0,025) i gama globulina (9,3, IKR 8,1-12,2 g/L vs. 12,5, IKR 9,6-19 g/L, p=0,029) u usporedbi sa bolesnicima s krioglobulinemijom tipa 3. Dijagnoza SLE-a postavljena je kod 21 bolesnika (tip 2 - 8 bolesnika vs. tip 3 - 13 bolesnika, p=0,137). Dijagnoza Sjögrenovog sindroma utvrđena je kod 8 bolesnika (tip 2 - 6 bolesnika vs. tip 3 - 2 bolesnika, p=0,002).
Zaključak: U analiziranoj skupini bolesnika najčešće su prisutne dijagnoze Sjögrenovog sindroma i SLE-a. Dijagnoza krioglobulinemije tipa 2 rjeđa je od krioglobulinemije tipa 3, a povezana je sa Sjögrenovim sindromom i izraženijim utroškom komplementa.Introduction: Cryoglobulins are proteins that precipitate at the temperature below 37°C, and their presence in the serum is called cryoglobulinemia. Cryoglobulinemia type 1 is associated with lympfoproliferative disorders, while cryoglobulinemia types 2 and 3 are associated with hepatitis C infection, neoplasms and systemic autoimmune diseases.
Aim: The aim of this study was to compare laboratory and clinical features between patients with cryoglobulinemia type 2 and 3.
Patients and methods: For this cross-sectional study data were obtained from the hospital archives. Patients positive for cryoglobulinemia in their serum over a period of three years were included in the study. Clinical and laboratory characteristics were analyzed and then compared between patients with cryoglobulinemia type 2 and 3.
Results: The presence of cryoglobulin was proven in a total of 38 patients (cryoglobulinemia type 2 – 10 female patients; cryoglobulinemia type 3 – 24 female patients and 4 male patients). In patients with cryoglobulinemia type 2, we identified a significantly higher value of rheumatoid factor (359.9, IQR 106.6-379.5 IU/ml vs. 20, IQR 13.4-93.4 IU/ml, p=0.007) and cryoprecipitate (385.5, IQR 216.5-492.5 mg/L vs. 119.5, IQR 82,3-156 mg/L, p<0.001), and a lower value of C4 (0.04, IQR 0.03-0.08 g/L vs. 0.13, IQR 0,06-0,19 g/L, p=0.025) and gamma globulin (9.3 , IQR 8.1-12.2 g/L vs. 12.5, IQR 9.6-19 g/L, p=0.029) compared to patients with cryoglobulinemia type 3. The diagnosis of SLE was made in 21 patients (type 2 - 8 patients vs. type 3 - 13 patients, p=0.137). the diagnosis of Sjögren's syndrome was established in 8 patients (type 2 - 6 patients vs. type 3 - 2 patients, p=0.002)
Conclusion: In the analyzed group of patients, the most common diagnoses were Sjögren's syndrome and SLE. The diagnosis of cryoglobulinemia type 2 was less common than cryoglobulinemia type 3, and it was associated with Sjögren's syndrome and a more pronounced hypocomplementemia
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Politics as Culture: Contribution of Political Science to Democratic Maturity
Get PDFČlanak propituje doprinos hrvatske politologije razvoju demokracije u Hrvatskoj. Fokus analize je pojam kulture o kojem autor govori u pet koraka. U prvom koraku je određena u modernom ključu, u drugom kao različita od prirode, a u trećemu kao različita od društva. U četvrtom se unutar politike razlikuje politička kultura od političke ekonomije i političkih ustanova, no u petom se pokazuje da je kultura nosivi dio politike i kao politics i kao policy i kao polity. Na temelju tih odredaba pokazuje se da je matica hrvatske politologije zaokupljena pretežito i u sve većoj mjeri izučavanjem upravo predmeta koji na prvi pogled pripadaju politici kao kulturi, i to u užem smislu političke kulture, te da se ona sama reproducira kao politička kultura.The article discusses the contribution of Croatian political science to the development of democracy in Croatia. The focus of the analysis is the concept of culture which author talks about in five steps. In the first step it is understood in the modern key, in the second step as different for nature and in the third as different from society. In the fourth step author differentiates political culture from political economy and political institutions, but in the fifth part there is an attempt to show culture as a fundamental part of politics, policy and polity. On the basis of these insights author shows that the matrix of Croatian political science is more and more devoted to scientific investigation of politics as culture as both study of political culture and as a source of development as politics as culture
Cryoglobulinemia in patients with systemic autoimmune diseases
No full textUvod: Krioglobulini su proteini koji precipitiraju pri temperaturi ispod 37°C, a njihova prisutnost u serumu zove se krioglobulinemija. Tip 1 krioglobulinemije veže se uz limfoproliferativne bolesti, dok se tipovi krioglobulinemije 2 i 3 povezuju s infekcijom virusom hepatitisa C, neoplazmama te sustavnim autoimunim bolestima.
Ciljevi: Cilj ovog istraživanja je usporediti laboratorijske i kliničke značajke između bolesnika s krioglobulinemijom tipa 2 i tipa 3.
Ispitanici i metode: Riječ je o presječnoj studiji temeljenoj na podacima iz bolničke arhive. Uključeni su bolesnici kojima je u razdoblju od tri godine dokazana prisutnost krioglobulina u serumu. Analizirana su klinička i laboratorijska obilježja koja su zatim uspoređena između bolesnika s krioglobulinemijom tipa 2 i 3.
Rezultati: Prisutnost krioglobulina dokazana je kod ukupno 38 bolesnika (krioglobulinemija tip 2 – 10 bolesnica; krioglobulinemija tip 3 – 24 bolesnice i 4 bolesnika). Kod bolesnika s krioglobulinemijom tipa 2 pronađena je značajno viša vrijednost reumatoidnog faktora (359,9, IKR 106,6-379,5 IU/ml vs. 20, IKR 13,4-93,4 IU/ml, p=0,007) i krioprecipitata (385,5, IKR 216,5-492,5 mg/L vs. 119,5, IKR 82,3-156 mg/L, p<0,001) te niža vrijednost C4 (0,04, IKR 0,03-0,08 g/L vs. 0,13, IKR 0,06-0,19 g/L, p=0,025) i gama globulina (9,3, IKR 8,1-12,2 g/L vs. 12,5, IKR 9,6-19 g/L, p=0,029) u usporedbi sa bolesnicima s krioglobulinemijom tipa 3. Dijagnoza SLE-a postavljena je kod 21 bolesnika (tip 2 - 8 bolesnika vs. tip 3 - 13 bolesnika, p=0,137). Dijagnoza Sjögrenovog sindroma utvrđena je kod 8 bolesnika (tip 2 - 6 bolesnika vs. tip 3 - 2 bolesnika, p=0,002).
Zaključak: U analiziranoj skupini bolesnika najčešće su prisutne dijagnoze Sjögrenovog sindroma i SLE-a. Dijagnoza krioglobulinemije tipa 2 rjeđa je od krioglobulinemije tipa 3, a povezana je sa Sjögrenovim sindromom i izraženijim utroškom komplementa.Introduction: Cryoglobulins are proteins that precipitate at the temperature below 37°C, and their presence in the serum is called cryoglobulinemia. Cryoglobulinemia type 1 is associated with lympfoproliferative disorders, while cryoglobulinemia types 2 and 3 are associated with hepatitis C infection, neoplasms and systemic autoimmune diseases.
Aim: The aim of this study was to compare laboratory and clinical features between patients with cryoglobulinemia type 2 and 3.
Patients and methods: For this cross-sectional study data were obtained from the hospital archives. Patients positive for cryoglobulinemia in their serum over a period of three years were included in the study. Clinical and laboratory characteristics were analyzed and then compared between patients with cryoglobulinemia type 2 and 3.
Results: The presence of cryoglobulin was proven in a total of 38 patients (cryoglobulinemia type 2 – 10 female patients; cryoglobulinemia type 3 – 24 female patients and 4 male patients). In patients with cryoglobulinemia type 2, we identified a significantly higher value of rheumatoid factor (359.9, IQR 106.6-379.5 IU/ml vs. 20, IQR 13.4-93.4 IU/ml, p=0.007) and cryoprecipitate (385.5, IQR 216.5-492.5 mg/L vs. 119.5, IQR 82,3-156 mg/L, p<0.001), and a lower value of C4 (0.04, IQR 0.03-0.08 g/L vs. 0.13, IQR 0,06-0,19 g/L, p=0.025) and gamma globulin (9.3 , IQR 8.1-12.2 g/L vs. 12.5, IQR 9.6-19 g/L, p=0.029) compared to patients with cryoglobulinemia type 3. The diagnosis of SLE was made in 21 patients (type 2 - 8 patients vs. type 3 - 13 patients, p=0.137). the diagnosis of Sjögren's syndrome was established in 8 patients (type 2 - 6 patients vs. type 3 - 2 patients, p=0.002)
Conclusion: In the analyzed group of patients, the most common diagnoses were Sjögren's syndrome and SLE. The diagnosis of cryoglobulinemia type 2 was less common than cryoglobulinemia type 3, and it was associated with Sjögren's syndrome and a more pronounced hypocomplementemia
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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