1,794 research outputs found
Surgical Management of Compound Odontoma Associated with Unerupted Tooth
No full textOdontomas represent the most common type of odontogenic benign jaws tumors among patients younger than 20 years of age. These tumors are composed of enamel, dentine, cementum, and pulp tissue. According to the World Health Organization classification, two distinct types of odontomas are acknowledged: complex and compound odontoma. In complex odontomas, all dental tissues are formed, but appeared without an organized structure. In compound odontomas, all dental tissues are arranged in numerous tooth-like structures known as denticles. Compound odontomas are often associated with impacted adjacent permanent teeth and their surgical removal represents the best therapeutic option. A case of a 20-year-old male patient with a compound odontoma-associated of impacted maxillary canine is presented. A minimally invasive surgical technique is adopted to remove the least amount of bone tissue as far as possible
Staley, Roberta
No full textcurrentAcademic Biography
BA (University of Calgary)
Diploma Journalism (Grant MacEwan)
MA Liberal Studies (Simon Fraser University)
Roberta Staley is an author, a magazine editor and writer, and a documentary filmmaker who has reported from such places as Afghanistan, Papua New Guinea, Kenya, El Salvador, Haiti, Colombia, Cambodia, South Africa, Israel, and New Zealand. She currently edits Enterprise magazine, and is a contributor to BC Business, the South China Morning Post Magazine, Ms. Magazine, Trek, the Canadian Chemical News, Corporate Knights, and Sculpture, among others. She is also a columnist for Just for Canadian Doctors/Dentists magazines. Roberta has published her first book, titled Voice of rebellion : how Mozhdah Jamalzadah brought hope to Afghanistan. It is a biography of Afghan-Canadian human rights activist Mozhdah Jamalzadah
Il ruolo del sistema nazionale di allerta precoce nella tutela della salute pubblica: strategie istituzionali e contributo tossicologico-forense per il contrasto alla diffusione delle nuove sostanze psicoattive
No full textLo scopo della presente tesi è di esporre il ruolo e le attività svolte dal Sistema Nazionale di Allerta Precoce (SNAP), istituito nel 2009 dal Dipartimento per le Politiche Antidroga (DPA) e coordinato dal punto di vista operativo e scientifico, a partire da giugno 2016, dall’Istituto Superiore di Sanità (ISS).
Si descrive l’organizzazione del flusso di informazioni e i dati epidemiologici relativi alla diffusione delle nuove sostanze psicoattive (NSP) sul territorio europeo e nazionale, attraverso le segnalazioni precoci della loro comparsa sul mercato clandestino e la tempestiva comunicazione di eventuali stati di allerta relativi a fenomeni potenzialmente pericolosi per la salute pubblica strettamente correlati al consumo di questi composti.
Obiettivo della tesi è anche l’illustrazione delle strategie messe in atto per far fronte alla rapida diffusione delle NSP nella Unione Europea e sul territorio italiano, presentando il supporto biotossicologico fornito dalla Unità Operativa di Tossicologia Forense dell’Università Sapienza di Roma (UO di Biotossicologia), nell’ambito delle attività del Sistema di Allerta.
A tale proposito verrà descritto il ruolo della UO di Biotossicologia nella revisione delle Comunicazioni provenienti dall’Osservatorio Europeo sulle Droghe e sulle Tossicodipendenze e la preparazione delle Informative relative ai sequestri operati dalle forze dell’ordine su territorio nazionale. Verrà inoltre esposto il contributo tecnico analitico offerto dalla suddetta Unità Operativa nei casi di accertamenti tossicologici effettuati su materiale non biologico oggetto di sequestro. Infine verranno presentate le revisioni sistematiche della letteratura internazionale, realizzate dall’Unità Operativa di Tossicologia Forense in merito alle NSP di maggiore diffusione e pericolosità sul territorio nazionale, sulla base dell’esperienza tecnico scientifica maturata durante la collaborazione con lo SNAP.
Capitolo 1: viene illustrata l’organizzazione del Sistema Nazionale di Allerta Precoce (SNAP) ed il ruolo cruciale che tale piattaforma riveste nella tutela della salute pubblica, coordinando lo scambio rapido di informazioni tra l’Osservatorio Europeo sulle droghe e sulle tossicodipendenze, le Forze dell’Ordine che operano i sequestri su territorio nazionale ed i Centri Collaborativi (ospedali, dipartimenti di emergenza, Ser.D.), al fine di facilitare la precoce individuazione di nuove sostanze psicoattive sul mercato clandestino e supportare le attività medico-sanitarie nel trattamento in emergenza di soggetti in stati di intossicazione acuta da NSP.
Capitolo 2: si introduce il concetto di nuova sostanza psicoattiva, effettuando una disamina della struttura chimica delle principali classi di appartenenza di questi composti ed approfondendo la delicata problematica dello stato di emergenza socio-sanitaria connesso al loro consumo.
Capitolo 3: viene descritto il supporto biotossicologico e tecnico analitico che l’Unità Operativa di Tossicologia Forense offre all’interno dello SNAP nella supervisione della documentazione e degli eventi che sono oggetto di attività del Sistema, sia a livello europeo che nazionale. Vengono, inoltre, presentate le revisioni sistematiche della letteratura internazionale realizzate dall’UO, in merito alle NSP maggiormente diffuse nel nostro Paese e che rappresentano ad oggi un grave rischio per la salute pubblica.
Capitolo 4: è dedicato alle conclusioni del lavoro di tesi, alle criticità del complesso sistema dedicato alla prevenzione ed alla lotta alla diffusione delle NSP ed agli obiettivi futuri, prevalentemente focalizzati sulla messa a punto di nuovi strumenti scientifici e legislativi sempre più efficaci per affrontare e combattere l’emergenza sociale e medico-sanitaria causata dalla indiscriminata espansione di queste nuove sostanze
Miniaturized analytical platform for cocaine detection in oral fluids by MicroNIR/Chemometrics
No full textIn the field of forensic toxicology, the use of non-destructive and easy-to-use analytical techniques deserves remarkable attention, especially in those situations involving public health and security. In addition, the miniaturization
and portability of one-touch devices for the detection of specific threats is required more and more.
In this study, a novel on-site MicroNIR/Chemometric platform was developed to perform a real-time prediction
of cocaine and its metabolites in non pre-treated oral fluid.
Simulated oral fluids were prepared in water in order to calibrate the instrumental response and the matrix
effect was consequently evaluated by processing spiked oral fluids collected from volunteers. The procedure was
optimized using a proper experimental design taking into account the equilibrium between cocaine and benzoylecgonine
in the range 10–100 ng-ml and validated by comparing results with the reference official method
(GC-MS).
The developed method was statistically able to discriminate oral fluid samples containing cocaine from 10 to
100 ng/ml and demonstrated to be not affected by the variability of the matrix as all the blank samples of
different volunteers (smokers and non smokers, assuming caffeine, sugars, chewing-gum or alcohol) as well as
spiked oral fluids were correctly predicted by the model. In addition, results from six real samples confirmed the
feasibility of the miniaturized platform to provide a correct identification of cocaine abuse and to propose the
MicroNIR as innovative personal screening system to prevent accidents and in cases involving workplace surveillance
Childhood overweight-obesity and periodontal diseases: is there a real correlation?
No full textObjective. The association between obesity and periodontitis has been extensively investigated in adults but not in young people. The aim of this study was to examine the association between overweight-obesity and periodontal disease in pediatric subjects.
Methods. Controlled cross-sectional study involving 100 school children of both gender (50 M and 50 F) between 7 and 12 years of age (mean age 9,19 +/- 1,57). Two groups were formed based on Body Mass Index value: test group with BMI >= 25 Kg/m(2) and control group with BMI <= 24 Kg/m(2). Diet intake and oral hygiene habits were recorded by a specific questionnaire and the periodontal clinical parameters were evaluated.
Results. The periodontal examination in the control group revealed a full-mouth plaque score (FMPS) value equal to 21.86% against 50.08% in the group of patients overweight/obese; the full-mouth bleeding score (FMBS) in the control group amounted to 12.7% against 26.24% of test group. No patient in either group included in the study presented a probing pocket depth (PPD) >= 3, so a significant difference regarding this value was not found. Regarding the frequency and quantity of food consumption, the number of obese patients who did not follow a balanced diet largely exceeded the number of normal-weight patients (70 versus 20%).
Conclusions. These results focus the attention on the negative impact of obesity on gingival health in young subjects, probably due to a combination of metabolic and inflammatory profiles and the result of a careless attitude towards prevention diseases of the oral cavit
Clinical management of a peri-implant giant cell granuloma
No full textPurpose. Implant therapy plays an important role in contemporary dentistry with high rates of long-term success. However, in recent years, the incidence of peri-implantitis and implant failures has significantly increased. The peripheral giant cell granuloma (PGCG) rarely occurs in peri-implant tissues and it is clinically comparable to the lesions associated with natural teeth. Therefore, the study of possible diseases associated with dental implants plays an important role in order to be able to diagnose and treat these conditions. Materials and Methods. This report described a 60-year-old Caucasian male who presented a reddish-purple pedunculated mass, of about 2 cm in diameter, associated with a dental implant and the adjacent natural tooth. Results. An excisional biopsy was performed and the dental implant was not removed. Histological examination provided the diagnosis of PGCG. After 19-month follow-up, there were no signs of recurrence of peri-implantitis around the implant. Conclusion. The correct diagnosis and appropriate surgical treatment of peri-implant giant cell granuloma are very important for a proper management of the lesion in order to preserve the implant prosthetic rehabilitation and prevent recurrences
Postface. Pour une esthétique hétéronome et plurielle
No full textBy discussing the essays collected in the volume, Roberta Dreon's paper focuses on the reasons that justify the very idea of a pragmatist aesthetic. This is done by considering that the association between the traditional, contemplative, disinterested, and anti-instrumental conception of aesthetic experience seems to preclude the possibility of characterizing it in practical or pragmatic terms.
The author argues that this is achieved on the one hand by a rethinking of the very notion of the "aesthetic" found in the philosophies of James and Dewey. This allows for supporting the idea that artistic practices are grounded in ordinary experience, and particularly in their aesthetic-qualitative aspects. On the other hand, the author argues that Dewey's aesthetics was convincingly pragmatist to the extent that it lucidly focused on the consequences of the autonomist conception of art and proposed a continuist, meliorist, and pluralist alternative capable of providing effective contributions to democratic and inclusive development
È possibile una teoria della razionalità? Il contributo di Hilary Putnam
No full textSecondo Putnam argomentare sulla natura della razionalità è l’attività per eccellenza dei filosofi. Sulla traccia di Putnam, l’autore esamina le principali teorie della razionalità presenti nel pensiero contemporaneo. Tali concezioni hanno il difetto di essere unilaterali, mentre la nozione di razionalità si rivela complessa, quindi una teoria della razionalità è possibile, benché non possa essere definitiva. In seguito l’autore cerca di individuare le caratteristiche fondamentali che competono alla razionalità, in opposizione tanto alla concezione positivista quanto al relativismo.According to Putnam, arguing about the nature of rationality is the typical task of philosophers. Following Putnam, in this paper the author examines the main theories of rationality to be found in contemporary thought. Whereas such views betray their own one-sidedness, the idea of rationality is very complicated. As a consequence, a theory of rationality is possible, but cannot be definitive. Furthermore, the author tries to highlight the chief features pertaining to rationality, opposing positivsm as well as relativism
First person - Roberta Besio
No full textFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Roberta Besio is first author on 'Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate', published in DMM. Roberta is a postdoc in the lab of Antonella Fortino at University of Pavia, Italy, investigating collagen and genetic diseases of the connective tissue
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