7,130 research outputs found
A Life Below with Joe Sulentic, Deadwood SD, Lawrence County
No full text4 x 5 b/w photograph, man examining a rock wallChinese Authority - Joe Sulentic, author of a book on the Chinese in Deadwood, points out a bit of history in the tunnels that run below Deadwood's streets. The Chinese came to Deadwood in the 1800's. SD Tourism Phot
Front Façade of Hawley Residence, Howard SD, Miner County
No full text35 mm slide, leafless trees in front of a two-story house with a bay window and an enclosed entry in a snow-covered landscapeDrawer info: McCook - Minnehaha; Minor CountyMinor County Howard Cameron Hawley House (Author of "Executive Suite") 2/84 M
High diagnostic yield of tuberculosis from screening urine samples from HIV-infected patients with advanced immunodeficiency using the Xpert MTB/RIF assay.
No full text: ABSTRACT:: We determined the diagnostic yield of the Xpert MTB/RIF assay for tuberculosis (TB) when testing small volumes of urine from ambulatory HIV-infected patients prior to starting antiretroviral therapy (ART) in South Africa. Compared to a gold standard of sputum culture, the sensitivity of urine Xpert among those with CD4 cell counts of <50, 50-100 and >100 cells/?L were 44.4%, 25.0% and 2.7% (P=0.001), respectively. Urine Xpert testing provides a means of rapid TB diagnosis in patients with advanced immunodeficiency and poor prognosis. These data are indicative of high rates of TB dissemination and renal involvement in this clinical population
Rear and Side Façade of Hawley Residence, Howard SD, Miner County
No full text35 mm slide, a two-story house with a bay window and an enclosed entry in a snow-covered landscapeDrawer info: McCook - Minnehaha; Minor CountyMinor County Howard Cameron Hawley House (Author of "Executive Suite") 2/84 M
Front and Side Façade of Hawley Residence, Howard SD, Miner County
No full text35 mm slide, leafless deciduous trees in front of a two-story house with a single-story addition and an enclosed entry in a snow-covered landscapeDrawer info: McCook - Minnehaha; Minor CountyMinor County Howard Cameron Hawley House (Author of "Executive Suite") 2/84 M
Issues of separation -individuation and gender role socialization in battered women: An investigation of the relationship between early developmental patterns and exposure to abusive relationships in adulthood
No full textIt has been estimated that between 21% and 34% of women in this country will be physically assaulted—slapped, kicked, beaten, choked, threatened or attacked with a weapon—by an intimate partner in adulthood (Browne, 1993). Some women who are involved in abusive relationships appear to be unable to remove themselves from the violent relationship. They baffle and frustrate those who attempt to help them when they initiate an escape, only to drop all efforts and return to their victimizers. This study investigated the relationship between early developmental patterns and involvement in abusive relationships in adulthood, based on reasons for women\u27s tolerance of abusive relationships hypothesized in the literature. Thirty-three women reporting relationship difficulties participated in the study. Based on their report of physical abuse in adulthood in the demographic questionnaire, they were divided into a group of eighteen Battered women and a group of fifteen non-Battered women. The two groups were compared on gender role (Bem Sex Role Inventory (Short Form), BSRI; Bem, 1981), gender identity (Solowey & Herman, 1986), level of separation-individuation disturbance (Separation-Individuation Inventory, SII; Christenson & Wilson, 1985), and level of object representation self-other differentiation (Object Representation Inventory Self-Other Differentiation Scale, ORI; Diamond, Kaslow, Coonerty, & Blatt, 1990). It was hypothesized that Battered women would achieve lower levels of object representations and self-other differentiation than Non-battered women. This hypothesis as stated was partially confirmed. Battered women achieved significantly lower levels of object representations and self-other differentiation when describing themselves (M = 4.7, SD = 2.1), than did Non-battered women, (M = 6.4, SD = 1.4, t (31) = −2.79, p = .009). They also achieved significantly lower levels of object representations and self-other differentiation when describing their partners (M = 4.4, SD = 2.1) than did Non-battered women (M = 6.2, SD = 1.6, t (31) = .012). In addition, levels of object representations and self-other differentiation in their descriptions of their fathers (M = 4.6, SD = 1.5) were significantly lower than those of Non-battered women (M = 6.3, SD = 1.6, t (26) = −2.67, p = .013). The two groups did not differ significantly, however, in level of separation-individuation pathology, gender role, or gender identity. These results suggest that early developmental patterns, specifically in significant relationships, are related to exposure to abusive relationships in adulthood. Implications of these findings are far reaching and call for future research in order to better understand how to prevent the development of the dynamics involved in abuse and domestic violence
Maturational pace and performance in female collegiate swimmers
No full textpurpose of this research was (1) to compare maturational pace between the female collegiate swimmers and non-athletic controls and (2) to determine whether maturational pace differs as a function of performance level. Maturational pace can be quantified retrospectively in women using age at menarche (AaM), with younger AaM corresponding to a faster maturational pace and older AaM a slower pace. Collegiate swimmers were significantly older at menarche (13.60 years ± 1.52 SD) than non-athletic controls (12.75 years ± 1.44 SD). In addition, the top-performing third of college swimmers in our sample were significantly older at menarche (14.06 years ± 1.59 SD) than the bottom-performing third (13.32 years ± 1.35 SD). We can conclude that (1) collegiate swimmers are older at menarche than controls and (2) swim performance is associated with later ages at menarche
The Pace of Biological Aging Partially Explains the Relationship Between Socioeconomic Status and Chronic Low Back Pain Outcomes
No full textEdwin N Aroke,1,* Jai Ganesh Nagidi,2 Vinodh Srinivasasainagendra,3 Tammie L Quinn,4 Fiona BAT Agbor,1 Kiari R Kinnie,1 Hemant K Tiwari,3 Burel R Goodin5,* 1Department of Acute, Chronic, and Continuing Care, School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA; 2Department of Computer Science, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA; 3Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA; 4Department of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA; 5Department of Anesthesiology, School of Medicine, Washington University, St Louis, MO, USA*These authors contributed equally to this workCorrespondence: Edwin N Aroke, School of Nursing, University of Alabama at Birmingham, 1701 2nd Avenue S, NB 470G, Birmingham, AL, 35294-1210, USA, Tel +1205-975-75700, Email [email protected]: Having a lower socioeconomic status (SES) is a predictor of age-related chronic conditions, including chronic low back pain (cLBP). We aimed to examine whether the pace of biological aging mediates the relationship between SES and cLBP outcomes – pain intensity, pain interference, and physical performance.Methods: We used the Dunedin Pace of Aging Calculated from the Epigenome (DunedinPACE) software to determine the pace of biological aging in adults ages 18 to 85 years with no cLBP (n = 74), low-impact pain (n = 56), and high-impact pain (n = 77).Results: The mean chronological age of the participants was 40.9 years (SD= 15.1); 107 (51.7%) were female, and 108 (52.2%) were Black. On average, the pace of biological aging was 5% faster [DunedinPACE = 1.05 (SD = 0.14)] in the sample (DunedinPACE value of 1 = normal pace of aging). Individuals with higher levels of education had a significantly slower pace of biological aging than those with lower education levels (F = 5.546, p = 0.001). After adjusting for sex and race, household income level significantly correlated with the pace of biological aging (r = − 0.17, p = 0.02), pain intensity (r = − 0.21, p = 0.003), pain interference (r = − 0.21, p = 0.003), and physical performance (r = 0.20, p = 0.005). In mediation analyses adjusting for sex, race, and body mass index (BMI), the pace of biological aging mediates the relationship between household income (but not education) level and cLBP intensity, interference, as well as physical performance.Discussion: Results indicate that lower SES contributes to faster biological aging, possibly contributing to greater pain intensity and interference, as well as lower physical performance. Future interventions slowing the pace of biological aging may improve cLBP outcomes.Pain language summary: Individuals of lower socioeconomic status (SES) experience worse outcomes from age-related chronic conditions, including chronic low back pain (cLBP). This work examines the relationship between SES, pace of biological aging, and cLBP intensity, interference with daily activities, and physical function. Lower SES correlates with a faster pace of biological aging, as well as cLBP pain intensity, pain interference, and physical performance. The pace of biological aging helps explain the relationship between household income and cLBP intensity, interference, as well as physical performance. Interventions targeting SES disparities may slow biological aging and improve cLBP outcomes.Keywords: socioeconomic status, health disparities, DunedinPACE, pace of biological aging, chronic low back pain, epigenetic cloc
Internalizing problems as a mediator in the relationship between low effortful control and internet abuse in adolescence: A three-wave longitudinal study
No full textThe aim of the study is to examine the relationships between early adolescents' low effortful control, middle
adolescents' internalizing problems and late adolescents' Internet abuse, focusing on the mediating role that
middle adolescents' internalizing problems may play in the relationship between early adolescents' low effortful
control and late adolescents' Internet abuse. The study followed a sample of 482 adolescents (245 boys and 237
girls) from early adolescence (wave 1; mean age=14.76, SD=0.63), through middle adolescence (wave 2;
mean age=15.77, SD=0.61), to late adolescence (wave 3; mean age=17.88, SD=0.57). The participants
completed self-report questionnaires on temperament in wave 1 and on internalizing problems and Internet
abuse in all three waves. Data from the mediation model showed that internalizing problems in middle adolescence
mediated the relationship between low effortful control in early adolescence and Internet abuse in late
adolescence
A pharmacological rationale to reduce the Incidence of opioid Induced tolerance and hyperalgesia: A review
No full textChronic pain is an important health and social problem. Misuse and abuse of opioids in chronic non-cancer pain management seem to be a huge problem, in some countries. This could probably affect the normal use of such analgesics in patients in need of them. Basic and clinical researches should find the solution to mitigate the potential damage. Dysregulation of mast cell and microglia activation plays an important role in the pathogenesis and management of chronic pain. Persistent mast cell activation sensitizes nociceptors and initiates central nervous system inflammatory processes, involving microglial cell activation and sensitization of spinal somatosensory neurons. Exposure of mast cells and microglia to opioids is well known to provoke activation of these non-neuronal immune cell populations, thereby contributing to an exacerbation of pro-inflammatory and pro-nociceptive processes and promoting, over the long-term, opioid-induced hyperalgesia and tolerance. This review is intended to provide the reader with an overview of the role for these non-neuronal cells in opioid-induced chronic pain and tolerance as a consequence of prolonged exposure to these drugs. In addition, we will examine a potential strategy with the aim to modulate opioid-induced over-activation of glia and mast cells, based on endogenous defense mechanisms and fatty acid amide signaling molecules
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