1,720,967 research outputs found
Mucoepidermoid carcinoma of the external auditory canal: case report.
Full text linkThis study reports a case of mucoepidermoid carcinoma (MEC) of the external auditory canal, which to date has only been described once in literature. Because the lesion is extremely rare, it is particularly difficult to classify it into stages following normal diagnostic parameters. This obviously limits the possibilities of treatment that consequently are either empirical or based on those of squamous cell carcinoma. The problems in the diagnosis and the possible methods of treatment of mucoepidermoid carcinoma are discusse
ACUTE PROMYELOCYTIC LEUKEMIA AND AURAL RECURRENCE: THE IMPORTANCE OF OTOSCOPY IN EARLY DIAGNOSIS
Full text linkRemissione Di Leucemia Acuta Promielocitica Complicata Da Patologia Otologica
No full textObjective: Acute promyelocytic leukemia (APL) comprises approximately
10% of the acute myeloblastíc leuketnias (AML). Extiameduilàry inuoluements
at presentdtion or relapse is an infrequent complication of AML and
extremely uficotnnlon in APL.
Material and Method: The case report of a 22-years-old female uith
APL who relapsed with extramedullary disease and a reuiew of the líterature
are presented.
Results: The patient with cytogenetically and molecularly confirrued
APL deueloped extramedullary relapse in middle ear and externai auditory canal
after tredtment with chemotberapy. Blood picture, bone ruarrolt) aspirdte
and lumbar puncture were negatiue for leukaemic cells. A reuiew of the literature
reuealed only eleuen cases of APL complicated by otological dísease.
tion if otouhea is present (relapse in tymp(tnic cauity with iy*pant, membyane
perforation) and/or CT scan (otological disease uith noimal eardrum).
The aboue to reduce exploratiue myringotomy in pat.i
Ipoacusia improvvisa
No full textWe performed a retrospective study during a one year period about patients complaining sudden hearing loss who went to emergency department. It was anlyzed the literature about treatment of this disease. Authors examined 115 patients affected by sudden hearing loss aged 16 to 60. All the patients were submitted to the otolaryngologist examination and then to an audiometric test. 78% out of all the examined patients were affected by sensorineural hearing loss. 13% out of all had mixed hearing loss. 9% had normal audiogram. The disease evaluation is strictly linked to its seriousness and the surgery timeliness, from which depend greater chances of recovery
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Clean-Contaminated Neck Surgery:Risk of Infection by Intrinsic and Extrinsic Factors
No full textObjective: To evaluate the risk of surgical wound infection (the most common complication in neoplastic clean-contaminated neck surgery) due to 10 intrinsic risk factors and 5 extrinsic risk factors. Design: Retrospective clinical study. Setting: Academic tertiary referral medical center. Patients: The study group included 115 patients with laryngeal carcinomas referred to our department from January 1, 1996, to August 31, 2002. Intervention: Fifty-seven patients underwent total laryngectomy and 58 underwent subtotal laryngectomy. Main Outcome Measures: The association between surgical wound infection due to 10 intrinsic risk factors and 5 extrinsic risk factors was evaluated with multivariate models. Results: Surgical wound infection occurred in 27 patients (23.5%). There was no significant increase in the incidence of infection in patients with extensive tumors (P.20) and in patients undergoing total laryngectomy and subtotal laryngectomy (P.20). The incidence of infection was significantly higher in patients with stage IV disease (P.01), in patients who underwent neck dissections (P.05), and in those presenting with lymph node metastases (P.001). Multivariate analysis showed that the presence of higher tumor stage is the best predictor of infection because it is the only significant factor (P.03) even when adjusting for others. The association between infection and the other factors considered in this study (age [P1.0], underweight [P=.26], anemia [P=.84], lymphocytopenia [P=.79 by Fisher exact test], number of preoperative hospitalizations [P1.0], preoperative radiotherapy [P=.57 by Fisher exact test], diabetes mellitus [P=.70 by Fisher exact test], cirrhosis, resection margins infiltrated by the tumor [P=.57 by Fisher exact test], and myocutaneous flap reconstructions [P=.82]) was not significant. Conclusion: The risk of surgical wound infection is correlated with a higher tumor stage and lymph node metastases; it is not associated with the extent of surgery or other factors considered
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