197,179 research outputs found
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Glendon Swarthout
No full textHosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
An integrative revision of the subgenus Liophloeodes (Coleoptera: Curculionidae: Entiminae: Polydrusini): taxonomic, systematic, biogeographic and evolutionary insights
No full textThe subgenus Liophloeus Weise, 1894 of Liophloeus Germar, 1817 (Coleoptera: Curculionidae: Entiminae: Polydrusini) consists of five morphologically similar species traditionally diagnosed based on the shape of the aedeagus. However, traits of the genital apparatus exhibit substantial and overlapping inter and intraspecific variation. All five species have the same ecological requirements and occur in central and eastern Europe, mostly in montane areas. The focus of this work was to verify the taxonomic status and validity of Liophloeodes species using a combination of molecular and morphometric techniques. Specimens were collected from the entire distribution range and initially assigned to a species according to the aedeagal shape. Genetic diversity and phylogeny of the subgenus were studied using three molecular markers (two ribosomal, 28S-D2 and ITS2, and one mitochondrial, COI). Moreover, several morphological characters were used for multivariate morphometric analyses. Finally, presence and prevalence of bacterial endosymbionts among species were investigated. Phylogenies based on ribosomal markers suggest that traditional species are correctly delimited, whereas COI phylogeny suggests hybridization and introgression occurring between Liophloeodes species. Morphometric analyses confirmed low interspecific diversity. Two major bacterial endosymbionts, Rickettsia and Wolbachia, were detected in many populations. We argue that Liophloeodes consists of young lineages whose evolution and diversification was possibly mediated by cyclic climate change event
Simulation of thermal plant optimization and hydraulic aspects of thermal distribution loops for large campuses
No full textFollowing an introduction, the author describes Texas A&M University and its utilities system. After that, the author presents how to construct simulation models for chilled water and heating hot water distribution systems. The simulation model was used in a $2.3 million Ross Street chilled water pipe replacement project at Texas A&M University. A second project conducted at the University of Texas at San Antonio was used as an example to demonstrate how to identify and design an optimal distribution system by using a simulation model. The author found that the minor losses of these closed loop thermal distribution systems are significantly higher than potable water distribution systems. In the second part of the report, the author presents the latest development of software called the Plant Optimization Program, which can simulate cogeneration plant operation, estimate its operation cost and provide optimized operation suggestions. The author also developed detailed simulation models for a gas turbine and heat recovery steam generator and identified significant potential savings. Finally, the author also used a steam turbine as an example to present a multi-regression method on constructing simulation models by using basic statistics and optimization algorithms. This report presents a survey of the author??s working experience at the Energy Systems Laboratory (ESL) at Texas A&M University during the period of January 2002 through March 2004. The purpose of the above work was to allow the author to become familiar with the practice of engineering. The result is that the author knows how to complete a project from start to finish and understands how both technical and nontechnical aspects of a project need to be considered in order to ensure a quality deliverable and bring a project to successful completion. This report concludes that the objectives of the internship were successfully accomplished and that the requirements for the degree of Degree of Engineering have been satisfied
Purification of antibodies using elastin like polypeptide based affinity precipitation
No full textAugust 2020School of EngineeringWith the final aim being the development of a continuous affinity precipitation setup for the purification of mAbs, the first part deals with an improvement to the affinity precipitation process. Optimal conditions for the new elution without resolubilization process are identified by carrying out a high-throughput study in batch mode. We successfully obtain high recoveries above 90% for both the mAbs tested.Future efforts can be carried out to scale-up the current affinity precipitation setup. The affinity precipitation process can also be extended to protein non-mAb therapeutics. Affinity ligand corresponding to the protein of interest can be identified by either phage display or rational design. The fusion of the ELP with the affinity ligand can be made. The optimization of the process is expected to be similar to the ELPZ-mAb process optimization. Further, research is being carried out by the Cramer and Przybycien to improve upon the proof of concept affinity precipitation setup developed in Chapter 3. In summary, continuous affinity precipitation is a versatile downstream processing technique that can potentially be used to purify a wide variety of therapeutics.Following the development of this novel affinity precipitation process, a lab-scale continuous affinity precipitation system was developed. This setup involves the binding of the mAb to ELP-Z, precipitation of the complex, capture and washing of the precipitates, and removal of the mAb from the ELP-Z precipitates, all in a continuous fashion. This system employs static mixers for efficient mixing during the binding and precipitation steps. The collected information was then employed to select appropriately sized depth filters (2um-0.2um) for the efficient capture and subsequent washing of ELP-Z-mAb precipitates.Low pH conditions were also evaluated for their ability to elute and recover pure mAb from the captured precipitate, again in a continuous fashion. Finally, appropriate cycling of depth filters was carried out to enable continuous operation of mAb capture, washing and elution. The developed continuous process was successful in purifying mAb with a high purity and yield.Continuous downstream purification of proteins is a field that is assuming increasing importance in the biotech industry. Affinity precipitation can help the industry in making a transition from the existing batch capture step using affinity chromatography to a continuous capture step. Elastin-like polypeptides with their property of reversible phase transition from soluble to insoluble precipitated state due to change in solution conditions can be used for affinity precipitation. This thesis focuses on the purification of monoclonal antibodies(mAbs) using ELP-Z, which is a fusion of an elastin-like polypeptide and the Z-domain of Protein-A.M
Intern experience at CH���M Hill, Inc.: an internship report
No full textIncludes author's vita"Submitted to the College of Engineering of Texas A&M University in partial
fulfillment of the requirement for the degree of Doctor of Engineering."Includes bibliographical referencesA review of the author's internship experience with CH���M HILL, Inc.
during the period September 1975 through May 1976 is presented. During this nine month
internship the author worked as an Engineer II in the Industrial Processes discipline of this
large consulting engineering firm... The author's prime responsibility was as one of three
lead design engineers on the design of a large wastewater treatment facility for a pulp mill
in Hoquiam, Washington owned by ITT Rayonier Inc. The work generally consisted of the design
of individual treatment units and associated piping and pumping. The purpose of the project
was to provide wastewater treatment capabilities that would satisfy the effluent limitations
(standards) imposed upon the mill by the State of Washington Department of Ecology and the
U.S. Environmental Protection Agency. The author's assignment also entailed necessary
interaction with the project manager and other CH���M HILL design engineers and support staff
members, the client's representatives, and representatives of two other consulting engineering
firms working on the project. Thus, the internship position at CH���M HILL provided considerable
experience coordinating the author's work with the work of other engineers, guiding the design
and administrative efforts of a support staff, and interacting regularly with the client and
other consulting firms. This broad exposure to a variety of engineering and organizational
problems provided a valuable educational experience
Transition to turbulence in a qblique shock-wave/boundary-layer interaction at M=15
No full textDirect numerical simulations are carried out for different forcing techniques to trigger transition during the interaction between an oblique shock-wave and a laminar boundary-layer at M = 1.5. Three forcing methods are used: a) forcing of oblique unstable modes, whose shape and behaviour are determined by the local linear stability theory, b) broadband free-stream acoustic disturbances, and c) a cold plasma flow control device. While the oblique-mode breakdown is dominant for low-amplitude forcing, long streaky structures drive the transition process in a high-amplitude disturbance environment. LES are also performed on the experimental setup by the Institute of Theoretical and Applied Mechanics (ITAM) from Novosibirsk State University with cold plasma actuation. As well as the disturbance type, the effect of Reynolds number and forcing amplitude will be investigated
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