2,219 research outputs found
An Unusual Pneumoperitoneum in an Extremely Low Birth Weight Preterm Newborn
No full textPneumoperitoneum (PP) is a radiological diagnosis, characterized by the presence of air under the diaphragm, that in 90% of cases results from a perforated viscus while in 10% of cases it is not associated to perforation, the so-called non-surgical or spontaneous PP. Spontaneous PP is rare at any paediatric and neonatal age. In the neonatal population, sporadic cases of spontaneous PP have been described, almost invariably following mechanical ventilation. We presented the case of an extremely low birth weight infant (ELBW) with spontaneous PP secondary to pneumomediastinum who has never underwent mechanical ventilation or cardiopulmonary resuscitation. (www.actabiomedica.it)
Validation of an hourly transcutaneous bilirubin nomogram in a population of term or late preterm newborn infants: preliminary results
No full textOBJECTIVE: The aim of this study was to asses the validity of the TCB nomogram
for the European population for predicting significant hyperbilirubinemia in
healthy term and late-preterm newborns.
METHODS: This observational study was conducted from February 2009 to December
2009 in the well-baby nurseries of Gemelli hospital of Rome. The predictive
ability of the skin bilirubin (TCB) nomogram was prospectively assessed in 926
neonates with gestational age 35 weeks. TCB was measured with Bilichek and total
serum bilirubin (TSB) was contemporary assayed by the standard spectrophotometric
method. Every neonate was assess for a single TCB and TSB value.
RESULTS: The mean TSB values was 8.2 +/- 3.2 mg/dl, while the mean TCB values was
9.5 +/- 3.6 mg/dl A sensitivity of 100% and a negative predictive value of 100%
were obtained with a single bilirubin determination applying the 75 degrees
percentile of our nomogram.
CONCLUSION: The 75 degrees percentile of the skin bilirubin nomogram for the
European population in the first 96 hours of life is able to predict all neonates
at risk of severe hyperbilirubinemia. It could facilitate a safe discharge from
the hospital and a targeted intervention and follow-up reducing the need for
blood samples
"The love that made hell, paradise." Ouida re-writing the Paolo and Francesca theme in Held in Bondage
No full textThe bestselling Victorian author Ouida reveals in her novels, and, in particular, Held in Bondage, an extraordinary knowledge od Dante, by using characters and themes from the Commedia. The Paolo and Francesca theme actually constitutes part of the plot of the novel and is to be found in many of her other works, short stories and non-fiction writing
HERStory Makers 2023: Francesca Fotheringham
No full textFrancesca Fotheringham is a postdoctoral research associate at the University of Edinburgh studying educational psychology with a focus on neurodiversity. She took part in HERStory Makers 2023.What is HERStory Makers?HERStory Makers is a social media competition for female-identifying early career researchers to share their research, their career journeys, and to inspire the next generation. Winners are selected by public vote. HERStory Makers is also part of EXPLORATHON, Scotland's contribution to European Researchers' Night.In 2022-23, EXPLORATHON Francescasupported by the Engineering & Physical Sciences Research Council [grant number EP/X020762/1].Author contributions to contentFrancesca conceived, planned, and recorded the video content. Kirsty Ross edited the video content to insert HERStory Maker credits, added subtitles, and reduce video length to below Twitter/X limit of 2 mins and 20 secs.</p
Influenza A (H1N1)-induced ischemic stroke in a child: case report and review of the literature
No full textIschemic stroke is an important cause of death and long term morbidity in children. Viral respiratory infections are emerging
as important risk factors responsible for ischemic stroke in this age group. The direct action of virus against cerebral vessels,
autoimmune reactivity, and increased production of cytokines are advocated as the main factors for causing ischemic stroke.
This study can be useful for clarifying some molecular aspects of H1N1 virus infection in children.
We report on the case of a H1N1-induced ischemic stroke in a Caucasian 2 year-old female. The cerebrospinal fluid samples
showed the positivity of polymerase chain reaction for influenza A (H1N1) infection, confirmed also by pharyngeal swab
culture. Increased levels of cerebrospinal fluid interleukin 6 and interleukin 1β were also detected.
H1N1 virus infection has been identified as an important cause of neurological involvement in children. The findings of
increased levels of Interleukin 6 and interleukin 1β in the cerebrospinal fluid of this child with H1N1 induced-ischemic stroke
seems to validate the role of pro-inflammatory cytokines as crucial mediators of cerebral thrombus formation
Medicina illuminata. La Biblioteca Lancisiana di Roma
No full textL'articolo presenta i codici miniati della Biblioteca Lancisiana di Roma. La prima parte, del coautore, è dedicata alla Biblioteca. La seconda parte, di F. Manzari, tratta dei manoscritti miniati, costituiti da due codici con le opere di Avicenna e dal Liber fraternitatis della Confraternita dell'Ospedale di Santo Spirito in Sassia a Roma.The article introduces the illuminated manuscripts of the Biblioteca Lancisiana in Rome. The first part of the article, by the co-author, is dedicated to the Library. The second part, by Francesca Manzari, illustrates the manuscipts; these are two manuscripts with the works of Avicenna and the Liber fraternitatis of the Confraternity of the Hospital of Santo Spirito in Sassia in Rome
Feasibility of transferring intensive cared preterm infants from incubator to open crib at 1600 grams
No full textBackground: Ability to maintain a normal body temperature in an open crib is an important physiologic competency generally requested to discharge preterm infants from the hospital. The aim of this study is to assess the feasibility of an early weaning protocol from incubator in preterm newborns in a Neonatal Intensive Care Unit. Methods. 101 infants with birth weight < 1600 g were included in this feasibility study. We compared 80 newborns successfully transferred from an incubator to open crib at 1600 g with 21 infants transferred at weight ≥ 1700 g. The primary outcome was to evaluate feasibility of the protocol and the reasons for the eventual delay. Secondary outcomes were the identification of factors that would increase the likelihood of early weaning, the impact of an earlier weaning on discharge timing, and the incidence of adverse outcomes. Newborns in the study period were then compared with an historical control group with similar characteristics. Results: Early weaning was achieved in 79.2% of infants without significant adverse effects on temperature stability or weight gain. Delayed weaning was mainly due to the need of respiratory support. Gestational age affected the likelihood of early weaning (OR 1.7282 95% CI: 1.3071 - 2.2850). In the multivariate linear regression, early weaning reduced length of stay (LOS) by 25.8 days (p < 0.0001). Conclusions: Preterm infants can be weaned successfully from an incubator to an open crib at weight as low as 1600 grams without significant adverse effect. Early weaning significantly reduces LOS in preterm newborns. © 2014 Barone et al.; licensee BioMed Central Ltd
Early weaning from incubator and early discharge of preterm infants: randomized clinical trial.
No full textOBJECTIVE: The goal was to assess the feasibility of earlier weaning from the
incubator for preterm infants.
METHODS: This was a prospective, randomized study with preterm infants with birth
weights of <1600 g who were admitted to a neonatal subintensive ward. Findings
for 47 infants who were transferred from an incubator to an open crib at >1600 g
(early transition group) were compared with those for 47 infants who were
transferred from an incubator to an open crib at >1800 g (standard transition
[ST] group). The primary outcome of the study was length of stay. Secondary
outcomes were the number of infants returned to an incubator, the growth velocity
in an open crib and during the first week at home, the proportions of
breastfeeding at discharge and during the first week at home, and the hospital
readmission rate.
RESULTS: The length of stay was significantly shorter in the early transition
group than in the standard transition group (23.5 vs 33 days; P=.0002). No
infants required transfer back to the incubator. Only 1 infant in the standard
transition group was readmitted to the hospital during the first week after
discharge. Growth velocities and individual amounts of breastfeeding were similar
between the 2 groups.
CONCLUSION: In this study, weaning of moderately preterm infants from incubators
to open cribs at 1600 g was safe and resulted in earlier discharge
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