1,721,015 research outputs found

    Cortical activation during imitative behavior: An fMRI study

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    A previous behavioural study on healthy subjects and callosotomized patients showed that subjects imitated mainly in mirror mode when free to choose the imitation mode, using the right limb to copy a left limb gesture of the facing model; when asked to use the same limb as the model, patients still perform in mirror mode, but controls imitated in anatomical mode, using the right limb for imitating a right limb gesture. These data suggest that the anatomical mode of imitation recruites both hemispheres, being linked to the integrity of the corpus callosum. The present study aims at investigating with fMRI the neural correlates of imitative perspective-taking, specially the anatomical mode. Functional MRI was performed in 10 control subjects of the previously tested groups, asked to Observe or Imagine-to-Imitate-with-the-same-limb, in separete runs, intransitive gestures. Different cortical activation in the two conditions were observed: opercular part of left inferior frontal gyrus, left inferior parietal lobule, right temporo-parietal junction and bilateral parietal opercular cortices were activated in Imagine-to-Imitate condition only. Present data confirm previous behavioural observations and indicate that neural circuitry underpinning the anatomical imitation of intransitive gesture likely requires the cooperation of both hemispheres, and therefore the integrity of the corpus callosum

    Emergency imaging of the spine in the non-trauma patient

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    Non-traumatic spinal emergencies include all those clinical situations that present with acute and/or rapidly progressive signs and symptoms of spinal cord-spinal nerve/root compromise. These can be a result of extrinsic spinal radiculomedullary compression or of intrinsic pathology. All of these conditions require rapid diagnostic analysis: the recognition of a compressive or expanding spinal cord-canal lesion makes it possible to determine a surgical solution, whereas its exclusion guides diagnosis and treatment in other directions. The main causes of non-traumatic acute and subacute myelopathic and/or radiculopathic syndromes are given in Table 1. © 2006 Springer Berlin Heidelberg

    Contrast-enhanced ultrasound in delayed splenic vascular injury and active extravasation diagnosis

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    INTRODUCTION: We describe the use of contrast-enhanced ultrasound (CEUS) in the diagnosis of delayed splenic vascular injury (DSVI) and active extravasation (DAE) during spleen injury follow-up. CEUS might be used instead of contrast-enhanced computed tomography (CECT) during spleen injury follow-up in order to reduce radiation exposure. OBJECTIVE: Assess diagnostic comparability between CEUS and CECT in the evaluation of DSVI and DAE during spleen injury follow-up. SUBJECTS AND METHODS: A total of 139 trauma patients (101 males, 38 females; mean age 48.6 years) with CECT diagnosed spleen injury were prospectively evaluated. They performed CEUS and CECT follow-up. All CEUS studies were performed using the same ultrasound scan, convex probe, mechanical index and ultrasound contrast agent dose. Twelve patients performed digital subtraction angiography (DSA) during follow-up, and the diagnostic performance comparability between CEUS and DSA was evaluated. RESULTS: CEUS showed 17 delayed spleen injury complications, and in 122 patients no complication was suspected. CECT diagnosed 16 delayed spleen injury complications in these 17 patients and showed a small DSVI in another patient. A total of 122 follow-up CT scans were negative. CEUS and CECT diagnostic comparability was 98.6%. Compared to DSA, CEUS showed a sensitivity of 100% and a positive predictive value of 91.7%. CONCLUSIONS: CEUS can be used during spleen injury follow-up instead of CECT. Positive CEUS examinations could perform CECT and, when necessary, DSA in order to confirm and treat spleen injury complications

    Neuropaediatric emergencies

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    This chapter covers the most common emergency situations encountered in neuropaediatrics, including cerebrovascular disease, head injuries, infections of the central nervous system (CNS) and intracranial hypertension. © 2006 Springer Berlin Heidelberg

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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