1,721,022 research outputs found
Gene Therapy of Glioblastoma Multiforme with a Bicistronic Retroviral Vector Expressing Human IL-2 and HSV-tK.
No full textEffect of differential growth conditions on the dTTP pool size in herpes simplex virus-infected Vero cells.
No full textA multilevel dynamic model for documenting, reactivating and preserving interactive multimedia art
Full text linkPreserving interactive multimedia artworks is a challenging research field due to their complex nature and technological obsolescence. Established preservation strategies are inadequate since they do not cover the complex relations between analogue and digital components, their short life expectancies, and the experience produced when the artworks are activated. The existence of many projects in this research area highlights the urgency to create a preservation practice focused on the new multimedia art forms. The paper introduces the Multilevel Dynamic Preservation (MDP) model, developed at the Centro di Sonologia Computazionale (CSC) of the University of Padova, which aims to preserve multimedia artworks through different levels of information (about the components, their relationship and the activated experiences) through various exhibitions and thus as a process or a dynamic object. The model has been developed through several case studies. This paper reports a specific and complex one: the “hybrid reactivation” of the Il caos delle sfere, a 1999 interactive installation by Italian composer Carlo De Pirro. The entire reactivation process aims at preserving its identity, rather than simply replicating the original installation, and consists of both the replacement of old and non-functioning components components (“adaptive/update approach”) and the reactivation of original parts (“purist approach“)-hence the name “hybrid reactivation”. Through this case study, it was possible to test and optimize the model in all aspects: from collecting old documentation and using it for reactivation to creating new documentation and archiving the entire artwork. The model allows us to preserve the artwork as a process of change, minimizing the loss of information about previous versions. Most importantly, it lets us rethink the concept of the authenticity of interactive multimedia art, shifting the focus from materiality to the experience and function that artworks activate. The model avoids recording both the last reactivation and the first exhibition as authentic. It records the process of transformation between reactivations. It is through this process that the authenticity of the artwork can be inferred
Efficacy of lung cancer screening appears to increase with prolonged intervention: results from the MILD trial and a meta-analysis
No full textHumans; Mass Screening; Early Detection of Cancer; Lung Neoplasm
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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