169,727 research outputs found
Azione del lievito di birra su alcuni parametri ematochimici del puledro
No full textOtto puledri Quarter Horse, suddivisi in due gruppi con lo stesso peso medio iniziale, sono stati alimentati con 5,5 kg di fieno di festuca e 2,5 kg di concentrati/giorno; la razione del secondo gruppo conteneva 100 g di lievito di birra fosforilato. All’inizio della prova, dopo 30 e 68 giorni i puledri sono stati pesati e sottoposti a prelievo di sangue. Dopo immediata centrifugazione, nel plasma sono stati analizzati ematocrito, proteine totali, albumina, urea, creatinina, Ca, P, Fe, Mg, Cu, Na, K, Cl, AST/GOT, ALT/GPT, g-GT, ALP e a-amilasi. Il consumo di sostanza secca è stato simile nei due gruppi, ma i cavalli che ricevevano lievito hanno fornito un accrescimento ponderale superiore e livelli plasmatici di NEFA più bassi (P<0,05). Inoltre, l’aggiunta di lievito alla dieta di base ha indotto un aumento delle concentrazioni plasmatiche di sodio (P<0,01), calcio (P<0,05) e fosforo, che indica un probabile aumento dell’assorbimento intestinale dei minerali; quale conseguenza a livello metabolico, i livelli di ALP erano più bassi (P<0,05) nei cavalli che ricevevano lievito. I risultati suggeriscono che l’integrazione della dieta con lievito di birra fosforilato può migliorare l’utilizzazione digestiva della fibra e la disponibilità dei minerali, come già rilevato con l’impiego di cellule vive
Growth response of juvenile dentex (Dentex dentex, L.) to varying protein level and protein to lipid in practical diets
No full textThe dentex (Dentex dentex L.) is a fast-growing sparid which represents a possible candidate for Mediterranean mariculture. As the basic nutrient requirements of this species are unknown, two feeding trials were carried out to identify suitable protein and lipid (energy) levels to be used in formulating practical diets for dentex. The experiments used groups of 30 specimens (each fish weighing 17 or 20.7 g) which were kept in 12 flow-through 160 1 tanks supplied with seawater at 21 min(-1) (temperature 20 +/- 1 degrees C; salinity 33 ppt). An initial 4-week trial was conducted to obtain a preliminary estimate of the optimal protein level. Triplicate groups were fed four practical diets with increasing levels of protein (44.3, 49.3, 55.7 and 58.9% dry matter (DM), over 90% of which was supplied by white fish meal) and a constant lipid content (17.3% DM; mostly supplied by fish lipids) to satiation. An analysis of the nutrient-weight gain relationship indicated that the optimal dietary protein level was 49.3% DM. In a second 60 day experiment, duplicate groups of fish were fed six diets with three protein levels (44.4, 49.5 and 55.8% DM) and two lipid contents (12.0 and 17.3% DM) within each protein level, nearly to satiation. Growth performance was lowest in fish given diets containing 44.4 or 49.5% protein and 12% lipid and was improved (P < 0.05) either with diets supplying 55.8% protein (regardless of dietary lipid)or 49.3% protein and 17.4% lipid. The results observed in the second trial suggest that when protein efficiency or retention are considered even dietary levels of 44.3% protein and 17.2% lipid (i.e. 24.3 g protein kJ(-1) calculated available energy) could be assumed as suitable levels for formulating practical diets for this species, providing high quality fish meal and oil are used
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Reactivities of Photoredox Generated Nickel‐Nucleophilic Reactive Organometallic Species
No full textDual photoredox catalysis has revolutionized the field of cross-coupling reactions, enabling the discovery of numerous highly efficient reactions. This breakthrough is attributed to the exceptional combination of nickel catalysis with photoredox catalysis. Nickel exhibits both oxidative addition and reductive elimination processes, and a wide range of oxidation states (ranging from I to IV) accessible within a single catalytic cycle. Furthermore, nickel complexes are capable of catalyzing various processes through radical mechanisms. The latest feature has proven to be incredibly potent in facilitating the formation of new C–C and C–X bonds (X = H, O, S, N). The powerful combination of photoredox and nickel catalysis reveals an expansive domain of unexplored possibilities. It offers unparalleled opportunities for improving reactions and exploring innovative pathways. Under photoredox conditions, it is possible to form nucleophilic reactive organometallic intermediates, useful in reaction with electrophiles. We have devoted a research program towards the rediscovery and use of organometallic reagents, introduced by Corey, Hegedus, and Semmelack many years ago. The results unveiled the extraordinary capabilities of photoredox catalysis, enabling the creation and efficient utilization of potent nucleophilic organometallic reagents under mild conditions, free from the need for strong bases or stoichiometric metal reductants
Convenient synthesis of polycyclic N(1)-C(2)-fused oxazino-indolones via [Au(I)] catalyzed hydrocarboxylation of allenes
No full textA new [Au(I)] catalyzed intramolecular hydrocarboxylation of allenes is presented as a valuable synthetic route to oxazino-indolones. The use of 3,5-(CF3)2–C6H3–ImPyAuSbF6 as the optimal catalyst (5 mol%) was necessary to guarantee (i) wide tolerance of functional groups, (ii) mild reaction conditions (r.t., 16 h), and (iii) high yields (up to 90%). Preliminary attempts towards an enantioselective version (81 : 19 er) are also documented by means of a new family of chiral C1-symmetric ImPyAuCl complexes
Growth response of juvenile dentex (Dentex dentex L.) to varying protein level and protein to lipid ratio in practical diets
No full textThe dentex (Dentex dentex L.) is a fast-growing sparid which represents a possible candidate forMediterranean mariculture. As the basic nutrient requirements of this species are unknown, twofeeding trials were carried out to identify suitable protein and lipid (energy) levels to be used informulating practical diets for dentex. The experiments used groups of 30 specimens (each fishweighing 17 or 20.7 g) which were kept in 12 flow-through 160 1 tanks supplied with seawater at 2 1min-’ (temperature 205 1°C; salinity 33 ppt). An initial 4-week trial was conducted to obtain apreliminary estimate of the optimal protein level. Triplicate groups were fed four practical diets withincreasing levels of protein (44.3,49.3, 55.7 and 58.9% dry matter (DM), over 90% of which wassupplied by white fish meal) and a constant lipid content ( 17.3% DM; mostly supplied by fish lipids)to satiation. An analysis of the nutrient-weight gain relationship indicated that the optimal dietaryprotein level was 49.3% DM. In a second 60 day experiment, duplicate groups of fish were fed sixdiets with three protein levels (44.4,49.5 and 55.8% DM) and two lipid contents ( 12.0 and 17.3%DM) within each protein level, nearly to satiation. Growth performance was lowest in fish given dietscontaining 44.4 or 49.5% protein and 12% lipid and was improved (P<O.O5) either with dietssupplying 55.8% protein (regardless of dietary lipid) or 49.3% protein and 17.4% lipid. The resultsobserved in the second trial suggest that when protein efficiency or retention are considered evendietary levels of 44.3% protein and 17.2% lipid (i.e. 24.3 g protein k.-’ calculated available energy)could be assumed as suitable levels for formulating practical diets for this species, providing highquality fish meal and oil are used
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
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