1,720,961 research outputs found
Poster 8: Effects of a Rehabilitation and Educational-Behavioral Program on Spinal Mobility in Patients with Ankylosing Spondylitis in Anti-TNFα Therapy: A Randomized Controlled Trial
Supervised training and home-based rehabilitation in patients with stabilized ankylosing spondylitis on TNF inhibitor treatment: a controlled clinical trial with a 12-month follow-up.
Objective: To assess the 12-month’s follow-up effects on pain, mobility, and physical function outcomes of a supervised training and home-based rehabilitation for ankylosing spondylitis patients stabilized with TNF-inhibitor therapy.
Design: Controlled clinical trial (sequentially determined allocation) with 12-months’ follow-up.
Setting: Patients’ homes.
Subjects: A total of 69 subjects were allocated to either a rehabilitation programme (rehabilitation group, n = 22), an educational-behavioural programme (educational group, n = 24), and to neither programme (control group, n = 23).
Interventions: Rehabilitation programme included supervised training and home exercises (stretching, strengthening, aerobic, chest, and spine/hip joint flexibility exercises); educational-behavioural programme included information on ankylosing spondylitis, pain and stress mechanisms, and control.
Main measures: Spinal pain intensity, Bath Ankylosing Spondylitis Metrology Index, Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Disease Activity Index, chest expansion, and cervical and lumbar spine active range of motion measured by a pocket goniometer.
Results: At baseline, the three groups exhibited comparable demographic characteristics and basal evaluations. Intra-group changes in the rehabilitation group from baseline to 12 months yielded statistically significant gains (p < 0.05) for all outcomes. At 12-months follow-up, compared with the control and educational-behavioural, the rehabilitation group exhibited significant differences in chest expansion (p = 0.001 and p < 0.001), Bath Ankylosing Spondylitis Disease Activity Index (p = 0.012 and p = 0.050), and in some goniometric measurements as cervical rotation (p = 0.007 and p = 0.014), toraco-lumbar rotation (p = 0.009 and p = 0.050), and total cervical movements (p = 0.009 and p = 0.001).
Conclusion: In comparison with the educational-behavioural programme or no intervention, supervised training and home exercises improved long-term outcome in patients with ankylosing spondylitis
Poster 7: Effects of a Rehabilitation and Educational-Behavioral Program on Pain, Disability and Quality of Life in Patients with Ankylosing Spondylitis in Anti-TNFα Therapy: A Randomized Controlled Trial
Medium-/long-term effects of a specific exercise protocol combined with patient education on spine mobility, chronic fatigue, pain, aerobic fitness and level of disability in fibromyalgia.
Objective. To propose a rehabilitation protocol able to produce immediate and long-termbeneficial effects on level of disability and overall performance in ADLs. Materials and Methods. Forty-one FM patients were randomized to an exercise and educationalbehavioral programme group (experimental group, EG = 21) or to a control group (CG = 20). Each subject was evaluated before, at the end (T1), and after 6 months (T6) from the conclusion of the rehabilitation treatment using the Fibromyalgia Impact Questionnaire (FIQ), the visual analogue scale (VAS), the Health Assessment Questionnaire (HAQ), the fatigue severity scale (FSS), the 6-minute walking test (6MWT), tender points count (TPC), and spinal active range of motion. The exercise protocol included 20 sessions consisting in self-awareness, stretching, strengthening, spine flexibility, and aerobic exercises, which patients were subsequently educated to perform at home. Results. The two groups were comparable at baseline. At T1, the EG showed a positive trend in FIQ, VAS, HAQ, and FSS scales and significant improvement in 6MWT and in most spinal active range of motion measurements (P between 0.001 and 0.04). The positive results were maintained at the follow-up. Conclusion. The proposed programme was well tolerated and produced immediate and medium-term beneficial effects improving function and strain endurance
Twelve-month follow-up of rehabilitation treatment forthe management of patients with ankylosing spondylitisin anti-TNF treatment. A randomized controlled trial
Introduction. Management ankylosing spondylitis (AS) requires a
combined pharmacological and non-pharmacological therapy. The
aim of this study was to assess the long term effects on pain, spine
mobility, physical function outcome of the rehabilitation program.
Materials and methods. Thirty-eight outpatients (8 women and 30
men, mean age 47.5±10.6 years) with clinically stabilized AS, in treatment
with a standard dose of TNF drugs for at least 9 months, were
consecutively enrolled into the study and randomly recruited to rehabilitation
(n=18; Rehabilitation Group, RG) or no rehabilitation treatment
(n=20; Control Group, CG). Rehabilitation treatment included 2
educational meetings and 12 exercise sessions (60 min. session, 2
times/week), including exercises for spine/hip joint flexibility, stretching,
chest and breathing expansion. The patients were taught the
programmed exercises and encouraged to perform them at home at
least three times per week. Outcome assessment after rehabilitation
treatment and 12-months follow-up included: spinal pain intensity by
the Visuo-Analogue Scale, Bath Ankylosing Spondylitis Metrology
Index, Bath Ankylosing Spondylitis Functional Index, Bath
Ankylosing Spondylitis Disease Activity Index, chest expansion, active
range of motion of cervical and lumbar spine measured by a
pocket goniometer (IncliMed®). Results. The 2 groups were comparable
in demographic characteristics and no significative differences
were found in clinical evaluations at baseline. Intragroup comparison
after the rehabilitation treatment (after 2 moths from the start)
showed that the RG significantly improved (p ≤ 0.050) in pain, functional
and spine mobility, compared to CG, and the results were
maintained to check at 12-month follow-up. Conclusion. Our results
show that the combination of an intensive group exercise and an
educational-behavioural program can provide promising results in
the long-term functional and mobility outcomes for the management
of patients with clinically stabilized SA in treatment with TNF
Trattamento riabilitativo in pazienti con spondilite anchilosante trattati con farmaco biologico: studio randonizzato controllato.
INTRODUZIONE La spondilite anchilosante (SA) è una malattia che colpisce elettivamente lo scheletro, a carico del quale col passare del tempo determina una diffusa rigidità, esito di infiammazione cronica del tessuto connettivo fibroso e dell’osso nelle sedi inserzionali di tendini e ligamenti. L’utilizzo dei farmaci biologici ha notevolmente migliorato il controllo sul dolore, la mobilità, il grado di disabilità, e la qualità di vita dei pazienti con SA.
SCOPO DEL LAVORO Lo scopo del presente studio è stato quello di valutare il ruolo della riabilitazione in pazienti affetti da SA.
MATERIALI E METODI Sono stati arruolati 58 pazienti affetti da SA in terapia con farmaco biologico (anti- TNFα) da almeno 9 mesi, randomizzati in tre gruppi, A, B e C, rispettivamente 19, 19 e 20 soggetti. I pazienti del gruppo A hanno partecipato a un programma riabilitativo con due incontri di educazione sulle caratteristiche e sulla prevenzione delle disabilità e con un ciclo di 10 sedute di cinesiterapia in palestra, effettuata a piccoli gruppi sotto la supervisione del fisioterapista. I pazienti del gruppo B hanno partecipato esclusivamente alle due sedute di educazione. I pazienti del gruppo C (gruppo di controllo) non hanno effettuato alcun intervento educativo o riabilitativo.
Dopo la raccolta dei dati demografici (sesso, età, durata di malattia), tutti i partecipanti sono stai sottoposti, al tempo 0, dopo 2 e 6 mesi, alle seguenti valutazioni: dolore e rigidità del rachide con la scala Visuo-Analogica (VAS), numero di articolazioni tumefatte e dolenti, espansione toracica, attività di malattia con l’indice metrologico specifico BASMI (Bath Ankylosing Spondylitis Metrology Index), articolarità del rachide (globale e divisa per distretti) attraverso misure di superficie fatte con un goniometro tascabile a indice pesante e ago-bussola (Inclimed®), e nastro centimetrato. L’indagine si concludeva con la somministrazione di alcune scale di autovalutazione riguardanti il dolore e la rigidità BASDAI (Bath Ankylosing Spondylitis Disease Activity Index), grado di funzionalità BASFI (Bath Ankylosing Spondylitis Functional Index) e la qualità di vita HAQ (Health Assessment Questionnaire) e MOS SF-36 (Medical Outcomes Study 36-Items Short-Form Healthy Survey).
RISULTATI A 6 mesi è stato evidenziato un miglioramento significativamente maggiore nel gruppo A, rispetto ai gruppi B e C, per mobilità del rachide, BASMI, espansione toracica, BASFI e HAQ e gran parte dei domini della scala SF-36. E’interessante sottolineare che il miglioramento del gruppo A era per gran parte già presente al 2° mese. Per quanto riguardava VAS e BASDAI, non sono risultate differenze statisticamente significative tra i gruppi A e B, ma entrambi presentavano un miglioramento significativo rispetto al gruppo C.
CONCLUSIONI Alla luce dei risultati di questo studio si ritiene che il trattamento riabilitativo possa ancora essere considerato un valido supporto terapeutico nei pazienti affetti da SA in trattamento con farmaco biologico
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
