1,720,957 research outputs found

    Effective pain reduction of non-pharmacological interventions for procedural pain during repetitive immunizations of children born pre-term

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    Psychological distress is common during pregnancy but the field of perinatal-psychology and related research as well as health services have focused their attention essentially on the post-partunl period. New data suggest that stress and psychopathology during pregnancy may be associated with significant risks for the mother and the baby and may lead to detrimental effects for both. Maternal psychopathology is related to reduced quality of life, higher rate of risk behaviors, postpartunl psychopathology, and to a decline in the quality of dyadic relationship. Antenatal stress and psychological disease and their underlying neuroendocrine changes are associated with poor pregnancy and birth outcomes. Maternal stress and psychopathology together with fetal vulnerability and other ~ediating factors, such as pharmachological treatment, may determme long-term consequences by altering developmental processes, affecting the structural development of certain brain areas circuits, and systems, as well as brain functioning. ' ~fter h~ving studied a sample obtained from the general population, thIS study focused on a selected and high risk sample of women diagnosed with psychopathology and recruited from a center specialized in Women's lifecycle mood disorders (psicheDonna Center-Milan). General aim: The general aim of this study was threefold: - to study different manifestations ofpsychological illness as well as to detect risk and protective factors in this selected sample of pregnant and postpartunl women - to analyze the characteristics of these women in order to understand the mechanisms underlying the interaction between protective and risk factors which may predict the course of psychopathological manifestations across pregnancy and beyond. - to analyze, in follow-up, the choice and efficacy of pharmacological and-or psychotherapy treatment of these women. Methods: A sample of91 pregnant and postpartunl women was enrolled from the Center. Women were subjected to a test battery in order to evaluate: - ~ndex ofpregnancy specific-related anxiety (PRAQ-R, Huizink) - mdex of State Anxiety and of Trait Anxiety, as defined by Spielberger (STAI-Y, Spielberger) - ananmestic data and risk and protection factors (scale constructed ad hoc and PDPI, Tatano Beck) - index of depressionlpostpartunl depression (EPDS, Cox). Conclusions and Considerations: Differences were found between ~is sample and the one from the general population, not only m test scores but overall in the role played by risk and protection factors. The presence of pregnancy-related specific anxiety (detected by PRAQ-R) was found more in the general population: a working hypothesis as to the underlying cause was developed. Women recruited from the Center are characterized by a peculiar configuration of risk and protection factors, where a previous history of psychopathology seems to play a prominent role in defining the sample. This type of evidence indicates a possible new key point with respect to intervention and prevention, that is, the previous history of psychopathology. Consequently we need to consider the necessity of different approaches in the use of screening tools, and in the development of preventive measures and healing programs, and tailor all activities and interventions to the patient in order to be effective. This has lead to new evidence-based perspectives for intervention

    Repetitive acute pain in infants born preterm: an age-specific nonpharmacological approach

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    Purpose of the study: to examine the age-related effectiveness of simple non-pharmacological interventions in reducing procedural pain in ex-preterm infants during a series of repetitive immunizations. Background: Infant pain is of critical interest, especially with respect to premature infants often exposed to protracted pain and recurring painful procedures. Despite the accumulating evidence that preterm neonates are highly sensitive to pain and that neonatal procedural pain is harmful and may lead to changes in neural development, treatment for painful procedures is limited. Children born preterm routinely undergo a series of monthly immunizations in order to prevent upper respiratory infections. These painful immunizations impact on an infant that experienced a mean of 14 stressful and painful procedures a day, during the period of hospitalization, which may have lasted for months. Given this, special attention is required to the development and use of age appropriate approaches that reduce the impact of painful procedures and to improve the treatment of repetitive pain in this particular group of vulnerable neonates. Methods: A Single Case Experimental Desing was used. 37 Italian children born pre-term were assigned to four non-pharmacological interventions (1: 25% sucrose solution in combination with oral stimulation by a pacifier; 2: visual–auditory distraction; 3: play interaction and 4: blowing soap bubbles). Reflecting the maturational level of the infants, considering age corrected for gestational age, each infant received the first intervention at his first immunization (out of five) and whenever no pain relieve was obtained, the next immunization was performed with the second intervention. Assessment of video-taped behaviour and crying, time to first cry, time to stop cry and total time required for the immunization procedure were used as outcome measures and assess by six independent observers. Results and Conclusions: following the maturation of the infant, visual-auditory distraction (using the more complex capacity of visual auditory integration), play interaction and blowing soap bubbles (using the capacity to participate in interactive play) all proved to be effective in delaying distress, reducing the facial display of pain and especially in reducing the time necessary to calm and console the infant. In addition, negative hospital experiences, length of stay together with gestational age and weight at birth should be considered important factors that influence the initial reaction to the first immunization. Sucrose in the presence of a pacifier significantly reduced pain and distress up to an age of 60 weeks corrected for gestational age. Furthermore these factors may underlie the extended efficacy of oral sucrose combined with a pacifier by altering the responsiveness of the immature nervous system to adverse events. This observation extends the effects of sucrose plus pacifier much beyond the period in which they are effective in term neonates. Finally, adjusting the method of non-pharmacological intervention according to age and maturational level will not only lead to the highest efficacy of pain management but will also lead to a reduction in stress as well as in time spend for the medical staff

    Psychopathology during pregnancy and postpartum: characterization of a selected high risk Italian sample

    No full text
    Psychological distress is common during pregnancy but the field of perinatal-psychology and related research as well as health services have focused their attention essentially on the post-partunl period. New data suggest that stress and psychopathology during pregnancy may be associated with significant risks for the mother and the baby and may lead to detrimental effects for both. Maternal psychopathology is related to reduced quality of life, higher rate of risk behaviors, postpartunl psychopathology, and to a decline in the quality of dyadic relationship. Antenatal stress and psychological disease and their underlying neuroendocrine changes are associated with poor pregnancy and birth outcomes. Maternal stress and psychopathology together with fetal vulnerability and other ~ediating factors, such as pharmachological treatment, may determme long-term consequences by altering developmental processes, affecting the structural development of certain brain areas circuits, and systems, as well as brain functioning. ' ~fter h~ving studied a sample obtained from the general population, thIS study focused on a selected and high risk sample of women diagnosed with psychopathology and recruited from a center specialized in Women's lifecycle mood disorders (psicheDonna Center-Milan). General aim: The general aim of this study was threefold: - to study different manifestations ofpsychological illness as well as to detect risk and protective factors in this selected sample of pregnant and postpartunl women - to analyze the characteristics of these women in order to understand the mechanisms underlying the interaction between protective and risk factors which may predict the course of psychopathological manifestations across pregnancy and beyond. - to analyze, in follow-up, the choice and efficacy of pharmacological and-or psychotherapy treatment of these women. Methods: A sample of91 pregnant and postpartunl women was enrolled from the Center. Women were subjected to a test battery in order to evaluate: - ~ndex ofpregnancy specific-related anxiety (PRAQ-R, Huizink) - mdex of State Anxiety and of Trait Anxiety, as defined by Spielberger (STAI-Y, Spielberger) - ananmestic data and risk and protection factors (scale constructed ad hoc and PDPI, Tatano Beck) - index of depressionlpostpartunl depression (EPDS, Cox). Conclusions and Considerations: Differences were found between ~is sample and the one from the general population, not only m test scores but overall in the role played by risk and protection factors. The presence of pregnancy-related specific anxiety (detected by PRAQ-R) was found more in the general population: a working hypothesis as to the underlying cause was developed. Women recruited from the Center are characterized by a peculiar configuration of risk and protection factors, where a previous history of psychopathology seems to play a prominent role in defining the sample. This type of evidence indicates a possible new key point with respect to intervention and prevention, that is, the previous history of psychopathology. Consequently we need to consider the necessity of different approaches in the use of screening tools, and in the development of preventive measures and healing programs, and tailor all activities and interventions to the patient in order to be effective. This has lead to new evidence-based perspectives for intervention

    Perinatal psychopathology: characterisation of a selected italian women sample

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    Psychopathology during pregnancy and postpartum period is a clinical-medical affair, as well as a social one. For many woman, pregnancy and postpartum may constitute a trigger, moreover if a woman is, or have been in her life, already affected by a manifest psychopathology or an asymptomatic one. Primary-preventive approach should be considered in preconception planning with all women in childbearing age who have or are at risk for psychopathology and psychiatric illness. For them, preventive and healing standardized and evidence-based programs are needed, in particular with respect of pharmacological treatment in a so critical period; even if is not proved that any specific psychotropic drug is completely safe, due to the fact that all psychotropic medication cross the placenta barrier, there are guidelines to follow. It's as well important to highlight that even if lots have to be studied, evidence suggests that untreated depression, rather than treatment with antidepressant during pregnancy, results in adverse outcomes. Resources, resilence, copying abilities assessment, risk and protective factors evaluation, together with pharmacological treatment costs-benefits balance, are the first steps for a personalized and effective healing program. from a study on a high risk and selected sample recruited from PsicheDonna Center-Milan-Italy (Macedonio-Melloni, Fatebenefratelli Hospital) will be discussed. This center is specialized in women's lifecycle mood disorders; the characterization of this peculiar sample will be presented, with respect to: - diagnosis -risk and protective factors configuration - assessment tools - pharmacological treatment planning - clinical healing activities adopted - intervention and preventive model developed

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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