1,720,974 research outputs found
Genetic characterisation of six miniSTR loci in an Italianpopulation sample
No full textAllele frequencies for the miniSTR loci D10S1248, D14S1434, D22S1045 (NC01) and D1S1677, D2S441, D4S2364 (NC02) were determined in a population sample from North-Western Italy. No significant deviations from Hardy–Weinberg equilibrium expectations were detected. The forensic usefulness of the selected miniSTRs was confirmed typing different aged samples and analysing 20 family trios with paternity confirmed
with CODIS autosomic STRs
Allele distribution of five X-chromosome STR loci in an Italian population sample
No full textPopulation genetic data for five X-chromosomal STR loci (DXS7423, DXS6789, DXS6795, DXS9898 and DXS8377) were generated by analysing a population sample from Northwest Italy. Intensive stutter bands were observed for the DXS8377 locus. The analysis of the 40 family trios segregation showed no new mutation
C4 and BF polymorphisms in a Turkish population and a group of etrurians of Tuscany (Italy)
No full textHighly informative Y-chromosomal haplotypesby the addition of three new STRs DYS437, DYS438 and DYS439
No full textThe Y chromosome STRs DYS437, DYS438
and DYS439 were selected from publicly available genome
databases and used to analyse an Italian population sample.
A tetraplex PCR reaction including the highly informative
DYS385 locus, was set up and used for the analysis
of 131 male samples to determine allele frequencies
and STR diversity values. The number of different haplotypes
and the haplotype diversity value found from the
analysis of the STRs included in the tetraplex reaction were
very similar to those found from the analysis of the basic set
of 7 Y-STRs (DYS19, DYS389I/II, DYS390, DYS391,
DYS392 and DYS393) previously carried out on the same
population sample. By combining the allelic states of the
11 Y-chromosomal STRs we could construct highly informative
haplotypes that allowed the discrimination of 93.8%
(120 out of 128) of the samples tested. This approach represents
a very powerful tool for individual identification
and paternity testing in forensic medicine
Forensic evaluation of tetranucleotide STR instability in lung cancer
No full textThe incidence of genetic instability affecting a set of STRs commonly used in forensic DNA analyses was assessed by performing a comparative study on 24 lung carcinomas with paired normal tissue samples. Out of 24 samples, 20 (83%) showed allele drop-out (ADO) in at least one STR locus. Allelic imbalance was detected at all the STR loci analysed. A small-cell carcinoma sample showed loss of heterozygosity (LOH), with complete deletion of one allele, at the D5S818 and D13S317 loci
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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