1,721,011 research outputs found
Design of a 4D breathing phantom for motion tracking studies in extra-cranial particle therapy
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Robustness of external/internal correlation models for real-time tumor tracking to breathing motion variations
No full textTargeting accuracy in real-time tumor tracking via external surrogates: a comparative study.
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A new system for in-room image guidance in particle therapy at CNAO
Get PDFThis paper describes the design, installation, and commissioning of an in-room imaging device developed at the Centro Nazionale di Adroterapia Oncologica (CNAO, Pavia, Italy). The system is an upgraded version of the one previously installed in 2014, and its design accounted for the experience gained in a decade of clinical practice of patient setup verification and correction through robotic-supported, off-isocenter in-room image guidance. The system's basic feature consists of image-based setup correction through 2D/3D and 3D/3D registration through a dedicated HW/SW platform. The major update with respect to the device already under clinical usage resides in the implementation of a functionality for extending the field of view of the reconstructed Cone Beam CT (CBCT) volume, along with improved overall safety and functional optimization. We report here details on the procedures implemented for system calibration under all imaging modalities and the results of the technical and preclinical commissioning of the device performed on two different phantoms. In the technical commissioning, specific attention was given to the assessment of the accuracy with which the six-degrees-of-freedom correction vector computed at the off-isocenter imaging position was propagated to the planned isocentric irradiation ge-ometry. During the preclinical commissioning, the entire clinical-like procedure for detecting and correcting imposed, known setup deviation was tested on an anthropomorphic radioequivalent phantom. Results showed system performance within the sub-millimeter and sub-degree range according to project specifications under each imaging modality, making it ready for clinical application
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Installation and testing of a newly designed patient setup and monitoring system for particle beam therapy
No full textAutomated fiducial localization in CT images based on surface processing and geometrical prior knowledge for radiotherapy applications
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