130,992 research outputs found

    Ricerche ecologiche nelle riserve della Foresta Umbra (Gargano).

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    Si descrivono le ricerche ecologiche botaniche condotte nelle riserve della Foresta Umbra (Gargano) nelle Riserve Pavari e Falascon

    Multifocal Intraocular Lenses: AcrySof ReSTOR® SN6AD2 + 2.5 D Lens

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    The AcrySof ReSTOR® +2.5 D is a multifocal intraocular lens (IOL) available since 2012. The IOL structure has a monofocal central area that ensures a high passage of light for distance vision and an apodized diffractive region with seven concentric rings. In this chapter, we review the current literature and our clinical experience in terms of visual acuity at different distances, quality of vision, and patient satisfaction. These results are also compared with those of other multifocal IOLs, comprising the previous model AcrySof ReSTOR® +3 D. The current increasing demand by cataract patients to be spectacle-free following surgery has increased the need for different types of multifocal IOLs. The AcrySof ReSTOR® +2.5 D is ideal for patients who require a good range of vision at intermediate distances without sacrificing the quality and quantity of distance vision

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Customized transepithelial photorefractive keratectomy for iatrogenic ametropia after penetrating or deep lamellar keratoplasty.

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    PURPOSE: To evaluate the safety and efficacy of customized transepithelial photorefractive keratectomy (PRK) for the correction of iatrogenic ametropia after penetrating keratoplasty (PKP) or deep lamellar keratoplasty.SETTING: Eye Clinic, Department of Neurological and Visual Sciences, University of Verona, Verona, Italy.METHODS: This study comprised 9 patients who had irregular astigmatism from 2.0 to 8.0 diopters (D) after PKP or deep lamellar keratoplasty. The ametropia was corrected with customized transepithelial PRK and the Corneal Interactive Programmed Topographic Ablation (CIPTA) software program (LIGI). Complete ophthalmic examinations were performed before and after surgery.RESULTS: The mean age of the patients was 39.2 years (range 31 to 59 years). All patients gained at least 2 Snellen lines of uncorrected visual acuity; 2 patients had an increase of at least 5 lines, and 3 patients had an increase of 8 lines. The mean refractive spherical equivalent changed from -2.98 D +/- 3.11 (SD) (range -7.25 to +3.00 D) before PRK to -0.58 +/- 0.84 D (range 0 to -2.50 D) at the last follow-up visit. One patient presented with grade 1 haze that did not improve with topical steroid therapy. No patient lost best spectacle-corrected visual acuity.CONCLUSION: Customized transepithelial PRK with the CIPTA software was a safe and effective treatment for irregular astigmatism after PKP or deep lamellar keratoplasty

    Exploring the inter-individual variability in flavor release: preliminary results

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    Factors affecting flavor release during food consumption have been widely debated in the literature for years. Due to the high complexity behind this phenomenon, several studies have undertaken the cause by mimicking the in-mouth processes by artificial devices or in vitro approaches (Salles et al., 2011). Nevertheless, studies involving in vivo approaches are not lacking (e.g. Aprea et al., 2006; Pedrotti et al, 2018), even if just few of them involved a large sample size (Repoux et al., 2011) which may be the key point to disclose new insight on the inter-individual differences on flavor release. Thus, here we present the preliminary results of a study, which aimed to investigate the inter-individual variability on flavor release during the consumption of a model food on a large healthy population. Ninety-three subjects (60.9 % female) between 22 to 68 years old participated in the study. Each subject, after filling in a socio-demographic questionnaire and giving an unstimulated saliva sample, consumed at least three replicates of a strawberry jelly candy following a specific bite-based procedure supported by a video tool. Simultaneously nose-space analysis with Selected-Ion Flow-Tube Mass Spectrometry (SIFT-MS) was carried out (SYFT VOICE 200 ultra, Syft Ltd, New Zealand). Flavour profiles information were extracted according to Romano et al. (2014) and then submitted to a Principal Component Analysis that revealed a negative effect of age and BMI on flavor release and persistence on the nasal cavity. No gender effect has been found. These preliminary results, based on a large sample of healthy people, highlighted some factors involved on the mechanisms of flavor release that may be the starting point to set up new approaches to investigate specific populations (e.g. bariatric or chemotherapy patients) where flavor release have a strong and a direct impact on their quality of life

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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