87,021 research outputs found
i lembi miocutanei di gran pettorale e di omento nel trattamento chirurgico delle sternotomie infette
Myo-cutaneous and greater omentum flaps in the surgical treatment of infected sternotomies
Optimizing Healthcare Ecosystem Performance-A Computational Study of Integrated Patient Assistance in Primary Care
Home health care professionals provide medical services to patients in their homes. With rising demand, it’s crucial to manage operational costs effectively while ensuring satisfaction for patients. This study presents a bi-objective optimization model aimed at resolving routing and scheduling challenges in home health care, with a focus on both system efficiency and patient accessibility. A Mixed-Integer Linear Programming Model (MILP) is developed. To tackle computational time challenges, we propose a Non-dominated Sorting Genetic Algorithm II to solve the multi-objective optimization problems. The evaluation of Pareto fronts demonstrates the method’s efficiency. We apply the method in a real-world case study to provide managerial implications
Laparoscopic indocyanine green sentinel lymph node mapping in endometrial cancer. Papadia A, Imboden S, Siegenthaler F, Gasparri ML, Mohr S, Lanz S, Mueller MD.
Abstract
BACKGROUND:
In endometrial cancer (EMCA), indocyanine green (ICG) sentinel lymph node (SLN) mapping has been reported, mainly in conjunction with robotic surgery.
OBJECTIVE:
We aimed to evaluate detection rates, sensitivity, and false negative (FN) rate of laparoscopic ICG SLN mapping in EMCA, and to evaluate differences in surgical outcomes between patients subjected to SLN biopsy only versus lymphadenectomy.
METHODS:
A retrospective analysis of EMCA patients undergoing ICG SLN mapping ± pelvic (PLND) and/or para-aortic lymphadenectomy (PALND) was performed. Detection rates were calculated for the entire cohort. Sensitivity and FN rates were calculated for patients undergoing lymphadenectomy after SLN mapping, and surgical outcome was compared among patients undergoing SLN mapping only versus lymphadenectomy.
RESULTS:
Of 75 patients, 33 underwent SLN mapping and 42 underwent SLN mapping followed by PLND/PALND. Overall and bilateral detection rates were 96 % (72/75) and 88 % (66/75), respectively, and the median number of removed SLNs, pelvic non-SLNs (NSLN) and para-aortic NSLNs was 3, 27, and 19, respectively. With a FN rate of 8.3 %, only one patient had bilateral FN SLNs and a metastatic para-aortal NSLN. Estimated blood loss (EBL) and operative (OR) time were significantly lower in patients undergoing SLN mapping only. No differences in complication rates between patients undergoing SLN mapping only and patients undergoing lymphadenectomy were recorded.
CONCLUSIONS:
Laparoscopic ICG SLN mapping has excellent overall and bilateral detection rates and a low FN rate. Compared with lymphadenectomy, SLN biopsy is associated with significantly lower EBL and shorter OR time
La riabilitazione del paziente parzialmente edentulo con perdita della dimensione verticale
Behaviour and activity patterns of the scuttle fly Megaselia oxybelorum Schmitz (Diptera : Phoridae) at nest aggregations of two host digger wasps (Hymenoptera : Crabronidae)
We report on a field study of the behavioural ecology of Megaselia oxybelorum Schmitz at nest aggregations of its hosts, the digger wasps Philanthus triangulum F. and Cerceris arenaria L. (Hymenoptera: Crabronidae). The flies flew across the P. triangulum nesting site both as single individuals and as females and males paired in copula, and the former case was recorded more than twice as often as the latter, while only single individuals were recorded at the C. arenaria site. Individuals both alone and in copula were seen at the P. triangulum site during the day roughly coinciding with the host provisioning activity, while at the C. arenaria site the fly's daily activity followed a bimodal trend in contrast to the normal distribution of the host provisioning. Visits of host nests were frequent at the P. triangulum site and null at the C. arenaria site. Single individuals spent less than 1 min inside a nest, while a female entering while still in copula spent generally 1-3 min inside, males exiting after 1-5 s, showing that only in this second case was an oviposition possible. The number of Megaselia oxybelorum increased with increasing host nest density and decreasing nearest neighbour distances of nests. Behavioural patterns of M. oxybelorum, when compared to other Megaselia spp. associated with fossorial Hymenoptera, showed differences possibly related to the biology of the hosts. In addition, some morphological variation within and between host sites are discussed
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