1,721,014 research outputs found
PTH assay in the first postoperative day after thyroidectomy early predictor postoperative hypocalcemia?
No full textBACKGROUND: The purpose of our study is to verify if PTH assay on the first postoperative day is a reliable early predictor of the onset of hypocalcemia.
METHODS: Between October 1999 and May 2000, a prospective trial involved 162 patients who underwent total or near total thyroidectomy at our institute. On the basis of PTH assay on first day we divided the patients in three groups: group A 28 patients with PTH 16 pg/ml.
RESULTS: In group A: 22 of 28 patients (78.5%) developed postoperative hypocalcemia and 20 (71.4%) needed replacement therapy; in group B: 14 of 34 (41.1%) had postoperative hypocalcemia and 10 (29.4%) received treatment; in group C: 23 of 100 (23%) became hypocalcemic after surgery but only 5 (5%) require calcium-vitamin therapy. A statistically significant correlation (p = 0.0017) was identified between post-operative PTH levels and lowest blood calcium values detected after surgery. The correlation between the drop in blood calcium levels after surgery and postoperative PTH (delta Ca) was statistically even more significant (p = 0.0002); the lower the postoperative PTH, the higher the absolute value of the delta Ca.
CONCLUSION: The authors suggest a clinical approach and pharmacological treatment protocol based on the outcome of PTH assay on the first post-operative day; a solution that is only apparently more costly because it in fact aims to ensure a more timely recourse to blood calcium monitoring or replacement therapy and also an earlier discharge of the patient
PRIMARY HYPERPARATHYROIDISM IN PATIENTS TREATED FOR NON-MEDULLARY THYROID CARCINOMA
No full textAbstract: The authors report three cases of primary hyperparathyroidism (HPT) in patients with differentiated thyroid carcinoma (DTC) developed a few years after initial surgical and radiometabolic treatment of DTC. The early diagnosis of HPT in these patients was made possible because of laboratory tests performed during follow-up, including the assay of serum calcium and serum phosphorus levels. Scinti-graphy using 99mTc-MIBI enabled the correct preoperative localisation of a single parathyroid adenoma in two of these patients and multiglandular pathology in the third
Incisional hernia treatment with progressive pneumoperitoneum and retromuscular prosthetic hernioplasty
No full textBackground and aim: Major incisional hernias of the abdominal wall often pose a serious surgical problem. The choice between simple suture repair and mesh repair remains uncertain. Methods: Seventy-seven patients underwent surgery to repair large abdominal incisional hernias, i.e., with parietal defects of 10 cm or more, by retromuscular prosthetic hernioplasty between 1996 and 1999. All patients were treated preoperatively by progressive pneumoperitoneum and were followed up for 2-5 years (mean 38.3 months). Results: Almost all patients tolerated the pneumoperitoneum; no postoperative death occurred. Six patients developed a subcutaneous infection but none of them required removal of the mesh. Two patients (2.6%) had recurrent incisional hernia. Conclusions: This study shows that pneumoperitoneum is useful in preparing patients for incisional hernioplasty. Retromuscular mesh repair represents an appropriate surgical procedure, particularly in view of its low rate of recurrence
Technique and results of laparoscopic adrenalectomy
No full textAbstract The aim of this report is to evaluate the benefits of laparoscopic adrenalectomy in terms of perioperative morbidity, complications and patients recuperation. We reviewed our experience with laparoscopic adrenalectomy in 47 consecutive patients who underwent adrenalectomy over a 4-year period. We used the lateral transperitoneal approach in all cases. The indications for adrenalectomy were Conn's adenoma in 24 patients, pheochromocytoma in 11, Cushing's syndrome in 3 and incidental adrenal tumour in 9. The average duration of surgery was 130 min (range, 60-300 min) and average adrenal gland size was 3.4 cm (range, 1.2-8 cm). Conversion from copy to laparotomy was necessary in three patients (6.4%), and postoperative complications occurred in two patients. There was no mortality. Laparoscopic adrenalectomy can be considered the method of choice for managing almost all adrenal masses, because of its low morbidity and short postoperative recovery. The main difficulty is to identify the adrenal gland, so several technical procedures are suggested
Incisional hernia treatment with progressive pneumoperitoneum and retromuscular prosthetic hernioplasty
No full textBACKGROUND AND AIM: Major incisional hernias of the abdominal wall often pose a serious surgical problem. The choice between simple suture repair and mesh repair remains uncertain.
METHODS: Seventy-seven patients underwent surgery to repair large abdominal incisional hernias, i.e., with parietal defects of 10 cm or more, by retromuscular prosthetic hernioplasty between 1996 and 1999. All patients were treated preoperatively by progressive pneumoperitoneum and were followed up for 2-5 years (mean 38.3 months).
RESULTS: Almost all patients tolerated the pneumoperitoneum; no postoperative death occurred. Six patients developed a subcutaneous infection but none of them required removal of the mesh. Two patients (2.6%) had recurrent incisional hernia.
CONCLUSIONS: This study shows that pneumoperitoneum is useful in preparing patients for incisional hernioplasty. Retromuscular mesh repair represents an appropriate surgical procedure, particularly in view of its low rate of recurrence
Identification of the nonrecurrent laryngeal nerve during thyroid surgery: 20-Year experience
No full textThe nonrecurrent laryngeal nerve, which is rarely observed during thyroidectomy, is at high risk for damage. During a 20-year period 6000 thyroidectomies were performed at our institution, and during these operations inferior laryngeal nerves were routinely identified in all the patients with a standard procedure based on the usual anatomic landmarks. A nonrecurrent laryngeal nerve was observed on the right side in 31 cases (0.51%), with no anatomic anomalies found on the left side. The nerve anomaly was diagnosed preoperatively in five patients. A vocal cord deficit, caused by a nerve lesion, was observed in four cases (12.9%). Our results suggest that the best way to avoid morbidity is routine identification of the nerve. This can be done by carefully identifying all the thyroid structures and being suspicious of the presence of the abnormality when the inferior laryngeal nerve is not found in a classic position
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Carcinoma differenziato della tiroide dopo il primo intervento: ruolo della scintigrafia MIBI e chirurgia radioguidata
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