1,722,154 research outputs found

    Pagano, L.

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    Il Sud e la cammino divide. Congiungere gli speroni per superarla

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    Lilia Pagano e Ugo Pagano partendo dalla considerazione che il turismo green, basato sulla percorrenza di lunghi tratti a piedi, sta guadagnando terreno rispetto a quello più tradizionale e inquinante osservano che nel Sud di Italia vi è un deficit anche di infrastrutture necessarie a questo nuovo tipo di turismo. Gli autori illustrano come, congiungendo con un cammino gli speroni che si affacciano sull’Adriatico e sul Tirreno, si potrebbe colmare questo divide recuperando anche numerosi borghi

    Zygomycosis in Italy: a survey of FIMUA-ECMM

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    The aims of the study were to analyze the clinical and epidemiological characteristics and treatments for patients who developed zygomycosis enrolled in Italy during the European Confederation of Medical Mycology of medical mycology survey. This prospective multicenter study was performed between 2004 and 2007 at 49 italian Departments. 60 cases of zygomycosis were enrolled: the median age was 59.5 years (range 1-87), with a prevalence of males (70%). The majority of cases were immunocompromised patients (42 cases, 70%), mainly hematological malignancies (37). Among non-immunocompromised (18 cases, 30%), the main category was represented by patients with penetrating trauma (7/18, 39%). The most common sites of infection were sinus (35%) with/without CNS involvement, lung alone (25%), skin (20%), but in 11 cases (18%) dissemination was observed. According to EORTC criteria, the diagnosis of zygomycosis was proven in 46 patients (77%) and in most of them it was made in vivo (40/46 patients, 87%); in the remaining 14 cases (23%) the diagnosis was probable. 51 patients received antifungal therapy and in 30 of them surgical debridement was also performed. The most commonly used antifungal drug was liposomal amphotericin B (L-AmB), administered in 44 patients: 36 of these patients (82%) responded to therapy. Altogether an attributable mortality rate of 32% (19/60) was registered, which was reduced to 18% in patients treated with L-AmB (8/44). Zygomycosis is a rare and aggressive filamentous fungal infection, still associated with a high mortality rate. This study indicates an inversion of this trend, with a better prognosis and significantly lower mortality than that reported in the literature. It is possible that new extensive, aggressive diagnostic and therapeutic procedures, such as the use of L-AmB and surgery, have improved the prognosis of these patients. PMID:19567354[PubMed - indexed for MEDLINE] Publication Types, MeSH TermsPublication TypesResearch Support, Non-U.S. Gov'tMeSH TermsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDrug Resistance, FungalFemaleHumansImmunocompromised HostInfantItaly/epidemiologyMaleMiddle AgedZygomycosis/diagnosisZygomycosis/drug therapyZygomycosis/epidemiology*Zygomycosis/etiology LinkOut - more resourcesFull Text SourcesESIFT srl - PDFOther Literature SourcesLabome Researcher Resource - ExactAntigen/LabomeEvaluations and comments from leading researchers and clinicians - Faculty of 1000 Medicin

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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