1,721,051 research outputs found
La filosofia al servizio di Omero. Per uno studio delle citazioni di filosofi nelle Quaestiones Homericae di Porfirio di Tiro
No full textDelineation of target volume for radioteraphy in SPECT images: stamement and analysis of two novel algorithms
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Confronto e validazione di due algoritmi innovativi per la segmentazione semi-automatica di immagini PET
No full textDosimetric principles of targeted radiotherapy and radioimmunotherapy
No full textThe use of radioisotopes in therapy represents a field of application that is constantly increasing. Therapy applications in nuclear medicine are expected to reach 40% of clinical activity in the 2020–2030 decade. Radionuclide therapy can be delineated into two main categories. The first approach uses the inherent biodistribution properties of the radionuclide, whereby it naturally accumulates in cancerous tissue. For example, radium-223 is a calcium-mimetic isotope incorporated in sites of increased bone turnover and osteoblastic activity. The second approach prefers the conjugation of the radionuclide to vectors such as monoclonal antibodies (mAbs), peptides, or small molecules to target tumor-associated antigens, allowing the possibility to treat a wide range of neoplastic pathologies. In principle, as is proper practice for therapeutic regimes with ionizing radiation, a dosimetric approach should be performed to optimize and personalize the treatment. The dosimetry of the lesion may be more effective in order to adapt and maximize the beneficial effects of the treatment
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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