1,567 research outputs found
Domoic Acid
No full texteditors, R.H. Waring, G.B. Steventon, S.C. Mitchell.; Includes bibliographical references and index.; Chapter 4. written by R. Andrew R. Tasker - Domoic acid - UPEI professor, Dept. of Biomedical Sciences.Source type: Print(0
Service Thinking in Design of Complex Sustainment Solutions
No full textDecision Engineering SeriesDelivering contracted performance levels for service based on the sustainment of complex engineering systems is a necessary but not sufficient condition for user satisfaction. Service is received in a context that is shaped by the state of mind of the customer—perceptions, biases, memories, intentions and patterns of thinking. Service teams need to understand the “mind of the customer“, complementing the “voice of the customer” used in requirements development. The chapter considers how service solutions are designed and suggests that the state of mind of the customer needs greater consideration during solution development. The service team functions in the social dimension to understand the customer’s mind and harmonises the service solution. The dominant thinking style in social space is characterised as “service thinking“, complementing the system thinking style which dominates in the conceptual space of product-service systems.L.A. Wood and P.H. Taske
Cytochrome oxidase subunit VI of Trypanosoma brucei is imported without a cleaved presequence and is developmentally regulated at both RNA and protein levels
Get PDFMitochondrial respiration in the African trypanosome undergoes dramatic developmental stage regulation. This requires co-ordinated control of components encoded by both the nuclear genome and the kinetoplast, the unusual mitochondrial genome of these parasites. As a model for understanding the co-ordination of these genomes, we have examined the regulation and mitochondrial import of a nuclear-encoded component of the cytochrome oxidase complex, cytochrome oxidase subunit VI (COXVI). By generating transgenic trypanosomes expressing intact or mutant forms of this protein, we demonstrate that COXVI is not imported using a conventional cleaved presequence and show that sequences at the N-terminus of the protein are necessary for correct mitochondrial sorting. Analyses of endogenous and transgenic COXVI mRNA and protein expression in parasites undergoing developmental stage differentiation demonstrates a temporal order of control involving regulation in the abundance of, first, mRNA and then protein. This represents the first dissection of the regulation and import of a nuclear-encoded protein into the cytochrome oxidase complex in these organisms, which were among the earliest eukaryotes to possess a mitochondrion
Focus : Thailand : Trade and investment. by Rodney Tasker
No full textVarious articles. p.33 Voters' second chance. p.38 Economy: Off the boil but still hot. p.40 Investment: A nap after gorging. p.42 The missing link. p.44 Exports: Looking to value-added. p.46 Environment: Cleaning up their act. p.48 Rural Poverty. p.49 Financial reforms
Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements
No full textOsteoporosis defines a causal relationship between reduced bone density, reduced mechanical competence of the bone tissue of the sufferers and concomitantly an increased risk of fracture in life. The aims of the present study is: (1) to provide further evidence to support the use of Quantitative Ultrasound (QUS) results from peripheral sites to provide a prediction of the density of the proximal femur; and (2) to provide rational evidence for the well-proven ability of QUS to predict directly ‘risk of fracture’. 20 femoral heads were obtained from 15 Caucasian females and 5 Caucasian males undergoing emergency surgery for a fractured neck of femur. QUS investigations of the calcaneus, proximal phalanx, distal radius and mid-shaft tibia were undertaken on the donors with 72 h of surgery. 128 fracture toughness samples and 20 compression cores were manufactured and tested. Significant relationships were found between QUS parameters determined in vivo and the apparent density (g/cm3) of the tissue at the proximal femur and both the fracture toughness and strength determined in vitro from the same donor individual. In this study we relate QUS results obtained in vivo to the actual apparent density of bone tissue from the proximal femur, donated by the same individual, and the fracture toughness and compressive strength. The study demonstrates the ability of QUS investigations at peripheral sites to accurately predict the density of bone from the proximal femur and provides evidence to support the use of QUS to predict the ‘risk of fracture’ directly.<br/
Using peripheral quantitative ultrasound to predict fracture mechanics and compressive properties at the head of the femur
No full textDiets of seabirds and consequences of changes in food supply
No full textResearch conducted by members of the Working Group on Seabird Ecology, on issues most likely to be raised within the ICES community concerning the foraging ecology of seabirds and waders, and the potential interactions between these groups of birds and fisheries.
A review of issues related to seabird consumption of fish and shellfish stocks, discards and mariculture as well as the trophic role and ecology of seabirds and waders: G. L. Hunt, W. A. Montevecchi, and M. F. Leopold.
Consumption of pre-recruit fish by seabirds and the possible use of this as an indicator of fish stock recruitment: S. P. R. Greenstreet, P. H. Becker, R. T. Barrett, P. Fossum, and M. F. Leopold.
Variation in prey taken by seabirds: M. L. Tasker, C. J. Camphuysen, and P.Fossum.
Evaluation of the role of discards in supporting bird populations and their effects on the species composition of seabirds in the North Sea: S. Garthe, U. Walter, M. L. Tasker, P. H. Becker, G. Chapdelaine, and R. W. Furness.
Exploration of the short-and medium-term consequences of a reduction in the amounts of fish discarded: M. L. Tasker, P. H. Becker, and G. Chapdelaine
Evidence for decadal scale variations in seabird population ecology and links with the North Atlantic oscillation: J. B. Reid, P. H. Becker, and R. W. Furness.
A review of the causes, and consequences at the population level, of mass mortalities of seabirds : C. J. Camphuysen, P. J. Wright, M. Leopold, O. Hüppop, and J. B. Reid.
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METAL NON-METAL AND OTHER INTERFACES - THE ROLE OF IMAGE INTERACTIONS
No full textThe authors argue that many phenomena associated with metal/nonmetal interfaces and similar situations with a large dielectric constant mismatch can be understood in terms of the image interactions due to charges in the nonmetal. The effects are additional to the traditional interactions, and are especially significant when no reactions between the phases occur. The image-charge concept allows one to rationalise much apparently unrelated information concerning: (a) the systematics of wetting and nonwetting of oxides by liquid metals; (b) the systematics of strong metal-support interaction in catalysis; (c) the spatial variation of stoichiometry in oxides grown on metals; (d) the dependence on thickness of the observed changes in the wetting by water of oxide grown on silicon; (e) some features of radiation-enhanced adhesion; and (f) a number of correlations of behaviour with nonmetal properties in which the precise choice of metal is not critical
Linking [M-3(III)] triangles with "double-headed" phenolic oximes
Get PDFStrapping two salicylaldoxime units together with aliphatic alpha,Omega-aminomethyl links in the 3-position gives ligands which allow the assembly of the polynuclear complexes [Fe7O2(OH)(6)(H(2)L1)(3)(py)(6)] (BF4)(5)center dot 6H(2)O center dot 14MeOH (1 center dot 6H(2)O center dot 14MeOH), [Fe6O(OH)(7)(H2L2)(3)](BF4)(3)center dot 4H(2)O center dot 9MeOH (2 center dot 4H(2)O center dot 9MeOH) and [Mn6O2(OH)(2)(H(2)L1)(3)(py)(4)(MeCN)(2)](BF4)(5)(NO3)center dot 3MeCN center dot H2O center dot 5py (3 center dot 3MeCN center dot H2O center dot 5py). In each case the metallic skeleton of the cluster is based on a trigonal prism in which two [(M3O)-O-III] triangles are tethered together via three helically twisted double-headed oximes. The latter are present as H2L2- in which the oximic and phenolic O-atoms are deprotonated and the amino N-atoms protonated, with the oxime moieties bridging across the edges of the metal triangles. Both the identity of the metal ion and the length of the straps connecting the salicylaldoxime units have a major impact on the nuclearity and topology of the resultant cluster, with, perhaps counter-intuitively, the longer straps producing the "smallest" molecules.</p
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