1,721,165 research outputs found

    Growth and body composition in the premature infant

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    Great interest has focused recently on the relationship between early nutrition, growth and subsequent health. Indeed, several studies have demonstrated that early life growth patterns exert programming effects on disease risk in later life, highlighting the key role played by early nutrition. Body composition, an index of quality of growth, is one of the factors apparently involved into this "programming" process. The American Academy of Pediatrics recommends to supply adequate amounts of nutrients so that growth and body composition of the preterm infant approximates that of the intrauterine fetus at the same gestational age. However, in clinical practice, the achievement of intrauterine growth rate and body composition is difficult Indeed, most preterm infants experience a significant postnatal growth retardation which can be accompanied by an increased and/or altered adiposity. The estimation of the dynamic features of body composition changes, in order to evaluate the quality, in addition to t he amount of weight gain plays a major role in the nutritional follow-up of preterm infants. Certainly, monitoring the somatic growth and the development of body composition in early infancy represents an extremely important clinical tool in the individualization of the nutritional management, the prevention and/or the recovery from the postnatal retardation and the identification of the subjects at high risk for developing the metabolic syndrome in young adulthood

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Consequences of prematurity on adult morbidities

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    Early life events play a key role in the development of adult diseases. Survival is promoted by the developmental adaptation to environment although advantage in the short term implies a long-term cost with regard to the development of adult morbidities. This is particularly true for the infant born prematurely as preterm birth is accompanied by a disruption of the normal organogenesis of multiple organ systems. This review will examine the effect of prematurity on the development of cardiovascular, kidney, respiratory and metabolic diseases in later life in addition to the neurodevelopment disabilities associated with preterm birth

    Quantitative ultrasound and dual-energy x ray absorptiometry in bone status assessment of ex-preterm infants

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    Preterm infants are at increased risk of low bone mass. Quantitative ultrasound (QUS) is a non-invasive method for assessment of bone status. The application of QUS in a cohort of ex-preterm infants was investigated. This study suggests that QUS cannot be used as a surrogate for dual-energy x ray absorptiometry
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