235 research outputs found
Il "vivo lune" della prospecttiva nella poesia di Alessandro Parronchi
Giovanna Ioli propone un discorso critico dell'opera poetica di Alessandro Parronchi, mettendo in risalto il tema della «prospettiva», che rappresenta la matrice della storia in versi del'autore fiorentino. Studioso dei fenomeni della visione, dello specchio, Parronchi ha grande competenza della storia e della fenomenologia di questo tema, documentata da una serie di saggi teorici d'arte e di letteratura. Tali interventi, a partire dagli Study sulla "dolce" prospettiva del 1964, che comprendono anche un capitolo importante sulla Commedia di Dante, rappresentano un discorso di metodo e si riflettono a tutto campo sull'opera di Parronchi, fino a diventare uno strumento fondamentale di lettura per le sue Poesie.Giovanna Ioli suggests a critical analysis of the poetical work of Alessandro Parronchi. She underlines the theme of the «perspective», which represents the poetical background of the Florentine author. Parronchi, who has investigated thephenomena of the vision, the mirror, is an expert of the history and phenomenology of this subject and his authority is proved by a series of the theorical essays on art and literature. These speeches, starting from the Study sulla "dolce" prospettiva of 1964, include also an important chapter on the Commedia by Dante. They represent a treatise of method and have an all round reflection on Parronchi¿s work so to become an essential instrument to understand his Poesie
Il «vivo lume» della prospettiva nella poesia di Alessandro Parronchi
Giovanna Ioli propone un discorso critico dell’opera poetica di Alessandro Parronchi, mettendo in risalto il tema della «prospettiva», che rappresenta la matrice della storia in versi dell”autore fiorentino. Studioso dei fenomeni della visione, dello specchio, Parronchi ha grande competenza della storia e della fenomenologia di questo tema, documentata da una serie di saggi teorici d’arte e di letteratura. Tali interventi, a partire dagli Study sulla ‘dolce’ prospettiva del 1964, che comprendono anche un capitolo importante sulla Commedia di Dante, rappresentano un discorso di metodo e si riflettono a tutto campo sull’opera di Parronchi, fino a diventare uno strumento fondamentale di lettura per le sue Poesie.Giovanna Ioli suggests a critical analysis of the poetical work of Alessandro Parronchi. She underlines the theme of the «perspective», which represents the poetical background of the Florentine author. Parronchi, who has investigated thephenomena of the vision, the mirror, is an expert of the history and phenomenology of this subject and his authority is proved by a series of the theorical essays on art and literature. These speeches, starting from the Study sulla ‘dolce’ prospettiva of 1964, include also an important chapter on the Commedia by Dante. They represent a treatise of method and have an all round reflection on Parronchi’s work so to become an essential instrument to understand his Poesie
Cytokine production by allergen Der p I- specific CD4+ T cell clones derived from a patient with severe atopic disease.
Natural killer stimulatory factor (NKSF/IL-12) induces Th1-type specific immune responses and inhibits the development of IL-4 producing Th cells.
A multicenter approach to evaluate omalizumab effectiveness in Samter’s triad
Omalizumab proved to be very effective in improving control of severe atopic asthma. Many small-sized studies suggested a potential role for omalizumab in the management of aspirin-exacerbated respiratory disease. The aim of this study is to describe the effectiveness of omalizumab in a multicentre group of patients with Samter’s triad. We retrospectively enrolled eight patients (5 females) with Samter’s triad who underwent at least one year of omalizumab therapy. Clinical data, functional parameters and questionnaires for asthma and nasal polyposis control were collected at baseline and follow-up. We observed a significant reduction of moderate-to-severe asthma exacerbations, together with an increase of FEV1 and a reduction of steroids intake. An improvement in asthma control and nasal symptoms was also reported. This multicenter study confirms the effectiveness of omalizumab in patients affected by Samter’s triad. Omalizumab may represent a potential therapeutic option for the management of this disease
Insights from a Case of Good’s Syndrome (Immunodeficiency with Thymoma)
Immunodeficiency with thymoma was described by R.A. Good in 1954 and is also named after him. The syndrome is characterized by hypogammaglobulinemia associated with thymoma and recurrent infections, bacterial but also viral, fungal and parasitic. Autoimmune diseases, mainly pure red cell aplasia, other hematological disorders and erosive lichen planus are a common finding. We describe here a typical case exhibiting all these clinical features and report a detailed immunophenotypic assessment, as well as the positivity for autoantibodies against three cytokines (IFN-alpha, IL-6 and GM-CSF), which may add to known immune abnormalities. A review of the published literature, based on case series and immunological studies, offers some hints on the still unsolved issues of this rare condition
Frequent T4-positive cells with cytolytic activity in spleens of patients with Hodgkin's disease (a clonal analysis).
Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones
Reversal of human allergen-specific CRTH2+ Th2 cells by IL-12 or the PS-DSP30 oligodeoxynucleotide
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