1,721,032 research outputs found

    La documentazione inquisitoriale a Siena nel medioevo : linee d’indagine

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    Constatato che non esiste uno studio relativo alla storia dell’inquisizione medievale a Siena, l’autrice tratta l’argomento dal punto di vista allargato delle tipologie documentarie sopravvissute. Ne deriva una specifica attenzione alla trasmissione testuale e specificamente al rapporto tra erudizione e documentazione, tra santità ed eresia; infine, uno sguardo speciale è dedicato ai libri dei conti degli inquisitori, una fonte ricchissima per trarre informazioni sulla “quotidianità” repressiva inquisitoriale.Starting from the point that a history of the medieval inquisition in Siena is to be written, the author deals with the subject from different points of view related to the different typologies of sources survived. Peculiar attention is paid to textual transmission, in particular to the link between erudition and documents, sanctity and heresy; finally, a special regard is offered to the account books, so rich to explain the everyday repression of the inquisitors

    I martiri aretini Gaudenzio e Columato: agiografia e culto dal medioevo all’età moderna

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    Studio agiografico sulla figura dei martiri aretini Gaudenzio vescovo e Columato diacono, vissuti in epoca paleocristiana. La Passio, di cui si fornisce l'edizione critica, è di epoca altomedievale (VIII secolo). Si prendono in considerazione anche i documenti d'archivio, la documentazione iconografica e le memorie seicentesche utili a ricostruire le vicende cultuali

    Un viaggio estatico nell’aldilà nel processo per la canonizzazione di Nicola da Tolentino

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    Il dossier delle fonti scritte e figurate relativo alla canonizzazione (1325-1446) e al culto di frate Nicola da Tolentino (1245-1305) costituisce, per varietà di tipologie e ricchezza di attestazioni, un caso di studio particolarmente adatto alla decodifica dei vettori e dei segni della memoria culturale. In particolare, gli atti del processo di canonizzazione (*) riflettono le espressioni molteplici di una religiosità ‒ dalla razionalità teologica e canonistica all’alterità ereticale e ortopratica ‒ che alla fine del Medioevo potevano coagularsi intorno alla tomba di un grande taumaturgo. Testimonianze processuali, ex voto di varie fogge e supporti, agiografie, edifici di culto, pitture monumentali e su ta-vola e altri mezzi di espressione e diffusione della sua fama di santità, in un gioco complesso di ri-mandi reciproci e nell’arco di pochi anni, istituirono una rete di significati e di strumenti comunicativi, di cui verrà esaminata in particolare l’interazione tra immaginario onirico e immaginario letterario par-tendo da un singolare episodio di guarigione miracolosa attribuito all’intervento del santo

    Familial clustering of arterial blood pressure, HDL cholesterol, and pro-insulin but not of insulin resistance and microalbuminuria in siblings of patients with type 2 diabetes

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    OBJECTIVE - To test the hypothesis that selected abnormalities cluster in type 2 diabetic families. Offspring of patients with type 2 diabetes have a 40-60% chance of developing type 2 diabetes and an increased frequency of impaired glucose tolerance (IGT) or unknown diabetes. These offspring also show metabolic abnormalities of type 2 diabetes, such as insulin resistance, high insulin and pro-insulin, low HDL cholesterol levels, arterial hypertension, and microalbuminuria. RESEARCH DESIGN AND METHODS - We studied 87 families including at least one type 2 diabetic patient, i.e., 87 probands and 146 siblings; 60 spouses of probands with no family history of diabetes were compared with siblings. Familial clustering was evaluated by 2 methods: concordance of siblings and probands for a given abnormality (method 1) and intraclass correlation coefficients of values within each family (method 2). RESULTS - At oral glucose tolerance testing, 24 siblings had type 2 diabetes, 31 siblings had IGT, and 14 spouses had IGT (P = 0.0012 vs. siblings). With method 1, familial clustering occurred for microalbuminuria, insulin resistance, arterial hypertension, HDL cholesterol and pro-insulin levels; with method 2, familial clustering was observed for the same variables except for microalbuminuria. With both method 1 and 2, familial clustering for insulin resistance disappeared, whereas familial clustering for arterial bloodpressure, HDL cholesterol, and pro-insulin remained after correction for BMI; after further restriction of analysis to probands and to siblings with normal glucose tolerance, familial clustering for pro-insulin was observed only with method 2. CONCLUSIONS - These data indicate that siblings of diabetic patients are at high risk for selected features of type 2 diabetes

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Development of a real-time polymerase chain reaction for the detection of Fusarium oxysporum f. sp. basilici from basil seed and roots

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    A real-time polymerase chain reaction (PCR) assay using a TaqMan® probe was developed to detect the causal agent of wilt and crown rot of basil from infected plants and seed in Italy. The aim of the study was to diminish testing time, previously performed using nested-PCR, and to create the conditions for future automation. The sensitivity of the assay was shown to be similar to the detection limit of the available nested-PCR procedure. The advantages of real-time PCR system include halving of the testing time, as well as the ability to identify both internally and externally infected seed to the sensitivity of 1 pg of genomic DNA. The assay was able to detect the presence of the pathogen in infected seed up to a sensitivity of 24 (SD: ±10) CFU per 100 seeds
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