1,720,975 research outputs found
Spettrometria per fluorescenza X applicata all'analisi elementale di capelli di antichi egizi
No full textInfluenza di differenti supporti sulla produzione e utilizzazione clinica di lembi di cheratinociti.
No full textTrace-element analysis of Egyptian mummy hair by x-ray fluorescence spectrometry
No full textQuantitative determinations of manganese, iron, copper, zinc and strontium in Ancient Egyptian hair samples were performed by tube-excited energy-dispersive X-ray fluorescence. The hair washing procedure was tested by scanning electron microscopy. A comparison was made between the obtained trace-element concentrations and the corresponding literature data. Particularly different concentration sequences of the examined elements were noted. In modern hair the decreasing order was zinc, iron, copper, strontium and manganese; in Ancient Peruvian hair it was iron, zinc, manganese, strontium and copper; in this work it resulted as iron, zinc, manganese, copper and strontium
4-Anilinoquinazolines endowed with antiangiogenic activity
No full textStarting from Vandetanib strucyure, we synthesized several 4-anilinoquinazoline derivatives employing our recently reported synthetic strategy. Synthesized compounds were eveluated for their inhibitory effects on cell proliferation and the active compounds were submitted to several other preliminary biological assays in order to investigate the mechanism of action. The antiproliferative effects of Vandetanib and quinazoline derivatives were related to a pro-apoptotic activity and showed a reversible growth activity. All compounds, as for the reference one, induced significant decreases in cell migration compared to that determined in control cultures.
Almost all the compounds showed very interesting anti-angiogenic activity and the ability to counteract the pro-angiogenic effects both in vitro and in vivo of cytokines (FGF-2 and VEGF). The effect on cell growth and migration induced was also evaluated in Human Umbilical Vein Endothelial Cells (HUVEC)
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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